A5015152368- Fungal and yeast genetics research
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Health and Medical Education
- Chromosomal and Genetic Variations
- Organizational Management and Innovation
- Educational Games and Gamification
- Fermentation and Sensory Analysis
- Wheat and Barley Genetics and Pathology
- Environmental Science and Technology
- Business, Innovation, and Economy
- Mobile Health and mHealth Applications
- Cognitive and psychological constructs research
- Frailty in Older Adults
- Higher Education Teaching and Evaluation
- Education and Art Integration
- Accounting and Organizational Management
- Digital Mental Health Interventions
- Service and Product Innovation
- Behavioral Health and Interventions
- Business, Education, Mathematics Research
- Educational Practices and Policies
- Educational Technology in Learning
- Occupational Health and Safety in Workplaces
- Historical and socio-economic studies of Spain and related regions
Carlsberg Laboratory
2012-2022
Instituto de Investigación Biomédica de Málaga
2019
Bremer Institut für Produktion und Logistik GmbH
2012-2014
University of Bremen
2013
Lund University
2007-2010
Two heterologous pathways have been used to construct recombinant xylose-fermenting Saccharomyces cerevisiae strains: i) the xylose reductase (XR) and xylitol dehydrogenase (XDH) pathway ii) isomerase (XI) pathway. In present study, Pichia stipitis XR-XDH Piromyces XI were compared in an isogenic strain background, using a laboratory host with genetic modifications known improve fermentation (overexpressed xylulokinase, overexpressed non-oxidative pentose phosphate deletion of aldose gene...
Cost-effective fermentation of lignocellulosic hydrolysate to ethanol by Saccharomyces cerevisiae requires efficient mixed sugar utilization. Notably, the rate and yield xylose arabinose co-fermentation must be enhanced.Evolutionary engineering was used improve simultaneous conversion in a recombinant industrial strain carrying heterologous genes for utilization pathways integrated genome. The evolved TMB3130 displayed an increased consumption under aerobic anaerobic conditions. Improved...
Improved agricultural and industrial production organisms are required to meet the future global food demands minimize effects of climate change. A new resource for crop microbe improvement, designated FIND-IT (Fast Identification Nucleotide variants by droplet DigITal PCR), provides ultrafast identification isolation predetermined, targeted genetic in a screening cycle less than 10 days. Using large-scale sample pooling combination with digital PCR (ddPCR) greatly increases size...
Lager beer brewing relies on strains collectively known as Saccharomyces carlsbergensis, which are hybrids between S. cerevisiae and eubayanus-like strains. yeasts particularly adapted to low-temperature fermentations. Selection of new yeast for improved traits or fermentation performance is laborious, due the allotetraploid nature lager yeasts. Initially, we have generated F1 by classical genetics, using spore clones complementation auxotrophies single upon mating. These were several...
Abstract Background In Saccharomyces cerevisiae galactose is initially metabolized through the Leloir pathway after which glucose 6-phosphate enters glycolysis. Galactose controlled both by repression and induction. The gene PGM2 encodes last enzyme of pathway, phosphoglucomutase 2 (Pgm2p), catalyses reversible conversion 1-phosphate to 6-phosphate. Overexpression has previously been shown enhance aerobic growth S. in medium. Results present study we show that overexpression under control...
Overexpression of the PGM2 gene encoding phosphoglucomutase (Pgm2p) has been shown to improve galactose utilization both under aerobic and anaerobic conditions. Similarly, xylose improved by overexpression genes xylulokinase (XK), enzymes from non-oxidative pentose phosphate pathway (non-ox PPP) deletion endogenous aldose reductase GRE3 in engineered Saccharomyces cerevisiae strains carrying either fungal or bacterial pathways. In present study, we investigated how combination these traits...
In the context of serious games industry, up to now most commonly used BM among developers representing SMEs consists in offering an individual product customer, based on tailored one-of a kind production. Such production has high costs and low re-usability leads long time-to-market. For industry dealing with products highly dependent technological advances, this implies risks for failure thus being put out business. Consequently, increasing number Serious Games are struggling survive. These...
Novel crop improvement methodologies, including the exploitation of natural genetic variation, are urgently required to feed our rapidly growing human population in context global climate change. Here we describe a ‘Fast Identification Nucleotide variants by DigITal PCR’ (FIND-IT) method for rapid identification pre-targeted or rare alleles large genomic populations. Libraries 500,000 individuals can be screened and desired isolated within two weeks. FIND-IT is widely applicable mining...
Approximately 25% of all carbohydrates in industrial worts are poorly, if at all, fermented by brewing yeast. This includes dextrins, β-glucans, arabinose, xylose, disaccharides such as isomaltose, nigerose, kojibiose, and trisaccharides panose isopanose. As the efficient utilization during wort’s fermentation impacts alcohol yield organoleptic traits product, developing strains with enhanced abilities to ferment subsets these sugars is highly desirable. In this study, we developed...
Introducción
 La incidencia y mortalidad del cáncer colorrectal exige la necesidad de su adecuado manejo a nivel asistencial, que necesariamente obliga conocer el perfil clínico demográfico las personas con este proceso enfermedad para mejorar los resultados salud.
 Objetivo
 Conocer paciente atendido en Málaga año 2016.
 Método
 Estudio descriptivo transversal, UGCI Oncología hospitales Málaga, 2016, por patología centro sanitario variables clínicas,...