A5024621945- Acute Myeloid Leukemia Research
- Hematological disorders and diagnostics
- Pancreatitis Pathology and Treatment
- Drug Transport and Resistance Mechanisms
- Amino Acid Enzymes and Metabolism
- Glycosylation and Glycoproteins Research
- Genomics, phytochemicals, and oxidative stress
- Phagocytosis and Immune Regulation
- Cell Adhesion Molecules Research
- Peptidase Inhibition and Analysis
- Adrenal Hormones and Disorders
- Lung Cancer Research Studies
- Parasitic infections in humans and animals
- Hereditary Neurological Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cellular Mechanics and Interactions
- Pharmacogenetics and Drug Metabolism
- Cholesterol and Lipid Metabolism
- Biomarkers in Disease Mechanisms
- Phytochemistry and Bioactive Compounds
- Hematopoietic Stem Cell Transplantation
- Synthesis and Biological Evaluation
- Bone and Joint Diseases
- Pancreatic function and diabetes
- Neuroinflammation and Neurodegeneration Mechanisms
Hunan Academy of Traditional Chinese Medicine
2025
West China Hospital of Sichuan University
2023
Sichuan University
2023
People's Hospital of Bishan District
2019
Chongqing Medical University
2014-2016
Chongqing Public Health Medical Center
2014
Shanghai Sixth People's Hospital
2007
Wayne State University
2006
University of Kentucky
2006
West China Medical Center of Sichuan University
1999
Objectives The aim of this study is to compare the quantity and quality scientific publications in transplantation fields that were written by researchers from Mainland China, Japan, South Korea Taiwan East Asia region. Settings Asia. Participants outcome measures Articles except editorials, conference abstracts, letters, news corrections published 25 journals 2006 2015 screened with Web Science database. number total annual articles, article types (study design site), impact factor,...
To demonstrate that intronic mutations in the myelin protein zero (MPZ) cause Charcot-Marie-Tooth neuropathy 1B (CMT1B) by disrupting MPZ splicing.We report a family with T>G transversion at invariant + 2 position intron 4 of (c.614 2T>G) abolishes 5' donor site recognition and is predicted to alter splicing. We obtained detailed clinical neurophysiologic analysis family. performed skin biopsies investigate splicing abnormalities, levels, localization myelinated nerves.Patients developed...
Summary Immunemediated hematopoietic suppression has been considered as one of significant pathophysiological changes in less‐advanced myelodysplastic syndrome (MDS). To explore deviation T cell subsets and its relationship to marrow cells apoptosis, measurement helper‐T (Th)/cytotoxic‐T (Tc) well the situation within this two (Th1/Th2 Tc1/Tc2) was performed by flow cytometry from 39 MDS patients 13 normal controls. Interferon (INF)‐γ tumor necrosis factor (TNF)‐α serum simultaneously...
1. Our objective is to investigate the alterations of hepatic drug transporters and metabolizing enzymes in hypercholesterolemia. Male Sprague-Dawley rats were fed high-cholesterol chows for 8 weeks induce Protein levels analyzed by iTRAQ labeling coupled with LC TRIPLE-TOF. 2. Total 239 differentially expressed proteins identified using proteomic analysis. Among those, protein (MRP2, ABCD3, OAT2, SLC25A12, SCL38A3, SLC2A2 SLC25A5) (CYP2B3, CYP2C7, CYP2C11, CYP2C13, CYP4A2 UGT2B) markedly...
1. Gallic acid is a main polyphenol in various fruits and plants. Inhibitory characteristics of gallic on CYP3A4 were still unclear. The objective this work hence to investigate inhibitory using testosterone as the probe substrate human liver microsomes (HLMs) recombinant (rCYP3A4) systems.2. caused concentration-dependent loss activity with IC50 values 615.2 μM 669.5 HLM rCYP3A4 systems, respectively. IC50-shift experiments showed that pre-incubation absence NADPH contributed 12- or 14-fold...
Human cytochrome P450 (CYP) 2A6 participates in the metabolism of nicotine and precarcinogens, thus deliberate inhibition CYP2A6 may reduce cigarette consumption therefore risk developing types cancer associated with smoking. The inhibitory effects mechanisms celery (Apium graveolens) extract on mouse CYP2A5 human activity remain unclear. These were investigated liver microsomes using coumarin 7-hydroxylation a probe reaction. Celery reduced activities vitro dose-dependent manner. In vivo...
Background: The objective of this study was to identify the top 100 cited articles in primary aldosteronism, and examine their characteristics. Methods: Science Citation Index Expanded database utilized search for published since 1900. Articles were evaluated several characteristics, including number citations, authorship, country institution origin, publication year, journal, design. Results: between 88 762 times, with a median 130. 1955 2012, majority aldosteronism publications (n=35)...