A5100744498- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- Drug-Induced Hepatotoxicity and Protection
- Plant Toxicity and Pharmacological Properties
- Phytochemistry and Biological Activities
- Soil Carbon and Nitrogen Dynamics
- dental development and anomalies
- Polysaccharides and Plant Cell Walls
- Kruppel-like factors research
- Bioactive Compounds and Antitumor Agents
- Plant Molecular Biology Research
- Forest, Soil, and Plant Ecology in China
- Tea Polyphenols and Effects
- Morinda citrifolia extract uses
- Metabolomics and Mass Spectrometry Studies
- Advanced Drug Delivery Systems
- Plant-based Medicinal Research
- Cleft Lip and Palate Research
- Toxin Mechanisms and Immunotoxins
- Cell death mechanisms and regulation
- Craniofacial Disorders and Treatments
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Wastewater Treatment and Nitrogen Removal
Wenzhou Medical University
2023
Yangzhou University
2022
Jiangxi University of Traditional Chinese Medicine
2018-2021
Daping Hospital
2016
Army Medical University
2016
University of Shanghai for Science and Technology
2014
Guizhou Cancer Hospital
2014
ZheJiang Institute For Food and Drug Control
2014
Chinese PLA General Hospital
2014
Jilin University
2014
Aims: Opening of the mitochondrial permeability transition pore (mPTP) is a critical event during ischemia/reperfusion (I/R) injury. Recently, we showed that Panax quinquefolium saponin (PQS) alleviates apoptosis cardiomyocytes by suppressing excessive endoplasmic reticulum stress (ERS) I/R Here, hypothesized this anti-apoptotic effect might be mediated through inhibition mPTP and apoptotic pathway. Methods: Ninety-six healthy male Sprague-Dawley rats were randomly divided into sham, I/R,...
An essential pathogenic element of acute limb ischemia/reperfusion (I/R) injury is microvascular dysfunction.The majority studies indicates that fibroblast growth factor 2 (FGF2) exhibits protective properties in cases I/R injury.Albeit its specific role the context yet unknown.An impressive post-reperfusion increase FGF2 expression was seen a mouse model hind I/R, followed by decline to baseline levels, suggesting key for survivability.FGF2 appeared reduce I/R-induced hypoperfusion, tissue...
Abstract Gynura procumbens (Lour.) Merr. is traditionally used as a raw material for making dumplings or steamed stuffed buns, and its fresh leaves are boiled with water tea. Herein, we established an ultra‐high–performance liquid chromatography–quadrupole time‐of‐flight mass spectrometry (UHPLC–Q‐TOF–MS/MS) combined characteristic ion filtration (CIF) strategy to rapidly screen active ingredients antioxidant anti‐inflammatory properties in G. . This involved screening the part of using...
Flowchart of the experimental procedures.
Apert syndrome (AS) is a common genetic in humans characterized with craniosynostosis.Apert patients and mouse models showed abnormalities sutures, cranial base brain, that may all be involved the pathogenesis of skull malformation syndrome.To distinguish differential roles these components head abnormal morphology AS, we generated strains specifically expressing mutant FGFR2 chondrocytes, osteoblasts, progenitor cells central nervous system (CNS) by crossing Fgfr2 +/P253R-Neo mice...
Abstract Embelia ribes is a traditional Chinese medicine compound used as remedy for various diseases. Nevertheless, detailed information regarding its chemical composition unavailable. Herein, ultra-high-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry was to characterize the components of E. ribes. A total 56 compounds, including 16 phenolics, flavonoids, 4 coumarins, 5 fatty acids and 15 other compounds were identified. Furthermore, phenolic flavonoid...
Gynura procumbens (GP) is a perennial herbal medicine and food homologous plant, which has been reported to have good hypoglycemic effect. However, its active components underlying mechanism of action are not clear. Here, we aimed confirm the effects GP on type 2 diabetes (T2DM) from several different aspects. We used UPLC/Q-TOF MS analyze metabolic patterns, included blood samples clinical subjects db / mice screen for serum markers pathways. also network pharmacology study targets in...
By the new environment-friendly surfactant (C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</inf> Alkyl glucoside quaternary ammonium) and inorganic modifier (aluminum chloride) modified bentonite, study on removal of algae with dosage organic modifier, concentration bentonite pH value. The result shows provides a good condition in after has been greatly improved structure performance. Under AlCl...