Zhikang Ye

ORCID: 0000-0003-0706-4464
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Venous Thromboembolism Diagnosis and Management
  • Health Systems, Economic Evaluations, Quality of Life
  • SARS-CoV-2 and COVID-19 Research
  • Nosocomial Infections in ICU
  • Antimicrobial Resistance in Staphylococcus
  • Acute Ischemic Stroke Management
  • Meta-analysis and systematic reviews
  • Pharmaceutical Practices and Patient Outcomes
  • Antibiotics Pharmacokinetics and Efficacy
  • Parathyroid Disorders and Treatments
  • Advanced Chemical Sensor Technologies
  • Respiratory Support and Mechanisms
  • Healthcare Decision-Making and Restraints
  • Blood groups and transfusion
  • Delphi Technique in Research
  • COVID-19 Impact on Reproduction
  • Bacterial Identification and Susceptibility Testing
  • COVID-19 and healthcare impacts
  • Atrial Fibrillation Management and Outcomes
  • Family and Patient Care in Intensive Care Units
  • Pancreatitis Pathology and Treatment
  • Helicobacter pylori-related gastroenterology studies
  • Clinical practice guidelines implementation

Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025

McMaster University
2019-2024

Impact
2019-2024

Guangzhou University of Chinese Medicine
2020-2024

Capital Medical University
2016-2023

Jinan University
2022-2023

Ningxia Hui Autonomous Region Peoples Hospital
2023

Ningxia Medical University
2023

China Pharmaceutical University
2023

University of Calgary
2023

Clinical practice guidelines or recommendations often require timely and regular updating as new evidence emerges, because this can alter the risk-benefit trade-off. The scientific process of developing accompanied by adequate implementation improve outcomes. To promote better management patients receiving vancomycin therapy, we updated guideline for therapeutic drug monitoring (TDM) published in 2015.Our complied with standards trustworthy guidelines, including timeliness rigor process,...

10.1093/cid/ciaa1536 article EN Clinical Infectious Diseases 2020-10-06

Abstract Clinical question What is the role of remdesivir in treatment severe covid-19? This guideline was triggered by ACTT-1 trial published New England Journal Medicine on 22 May 2020. Current practice Remdesivir has received worldwide attention as a potentially effective for covid-19. After rapid market approval US, already being used clinical practice. Recommendations The panel makes weak recommendation use covid-19 while recommending continuation active enrolment patients into ongoing...

10.1136/bmj.m2924 article EN BMJ 2020-07-30

Guideline development should be based on the quality of evidence, balance benefits and harms, economic evaluation patients' views preferences. Therefore, these factors were considered in a new guideline for therapeutic drug monitoring (TDM) vancomycin. To develop an evidence-based vancomycin TDM to promote standardized clinical practice China. We referred WHO Handbook Development used Grading Recommendations Assessment, Evaluation (GRADE) system rate evidence grade strength recommendations,...

10.1093/jac/dkw254 article EN Journal of Antimicrobial Chemotherapy 2016-07-11

Objectives ‘National Special Stewardship in the Clinical Use of Antibiotics’ was put forward July 2011 China. We aimed to retrospectively evaluate impact antimicrobial stewardship (AMS) managed by clinical pharmacists on antibiotic utilisation, prophylaxis and resistance (AMR). Design This a retrospective observational study trends use AMR context AMS. Setting Beijing Chaoyang Hospital, 1400-bed tertiary hospital, Data participants Antibiotic prescriptions from 820 doctors included all...

10.1136/bmjopen-2018-026072 article EN cc-by-nc BMJ Open 2019-08-01

BackgroundThe goal of this systematic review was to examine the efficacy and safety proton-pump inhibitors for stress ulcer prophylaxis in critically ill patients.MethodsWe included randomized trials comparing versus placebo or no adults, performed meta-analyses, assessed certainty evidence using Grading Recommendations, Assessment, Development, Evaluations approach. To explore effect on mortality based disease severity, a subgroup analysis conducted combining within-trial data from two...

10.1056/evidoa2400134 article EN NEJM Evidence 2024-06-14

KEY POINTS On Mar. 11, 2020, the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) a pandemic. The worldwide spread of COVID-19 represents profound threat to human health. Patients with present primarily fever, cough, and myalgia or fatigue, sometimes

10.1503/cmaj.200648 article EN cc-by-nc-nd Canadian Medical Association Journal 2020-04-29

Plastic packaging waste, such as polyethylene terephthalate (PET) has increased significantly in recent decades, arousing a considerable and serious public concern regarding the environment, economy, policy. recycling is useful tool to mitigate this issue. Here, feasible study was performed investigate potential of novel method for identifying virgin recycled PET. Ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) combined with various...

10.1080/19440049.2023.2227732 article EN Food Additives & Contaminants Part A 2023-07-06

Inappropriate use of stress ulcer prophylaxis (SUP) is common in many hospitals. High-quality clinical practice guidelines (CPGs) produce better patient outcomes and promote cost-effective care. Thus, the objective this study was to evaluate quality CPGs for SUP.A search conducted SUP using PubMed, Embase, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature database (CBM), guideline websites Google (until March 1, 2015). The independently assessed by two assessors...

10.1371/journal.pone.0155020 article EN cc-by PLoS ONE 2016-05-06

The cleaning device is an important part of combine harvesters, as its superior or inferior performance directly affects the harvester greatly. With increasing rice yield, current single-duct declines greatly, and causes a large grain sieve loss level direct for farms. To optimize existing to meet feeding rate requirement, firstly, terminal velocity MOG (material other than grain) different varieties was experimentally measured by custom-made device. effects moisture content grains length...

10.3390/agriculture12091457 article EN cc-by Agriculture 2022-09-13

Objective: To evaluate the diagnostic performance of artificial intelligence-assisted systems in cervical cytopathological examination. Methods: Cervical cytology slide data were retrospectively collected from four hospitals for external validation developed system. Subsequently, prospective collection was conducted human-machine assisted studies. Results: In retrospective study, a total 3 162 valid samples as data. The system showed an area under curve (AUC) 0.890 (95%CI: 0.878-0.902),...

10.3760/cma.j.cn112338-20240711-00412 article EN PubMed 2025-03-10

Cardboard‐like off‐odour in yoghurt can negatively impact consumer acceptability. Herein, a method has been developed to analyse off‐odorants using headspace solid‐phase microextraction coupled with gas chromatography–mass spectrometry. Of 56 volatile organic compounds identified, 8 were active responsible for cardboard‐like off‐odour, including 2, 2‐dimethyl‐propanoic acid and 3‐methyl‐2‐pentanone, which newly identified yoghurt. Hexanol hexanal found be indicators of quality deterioration....

10.1111/1471-0307.12981 article EN International Journal of Dairy Technology 2023-06-02
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