Weiduan Zhuang

ORCID: 0000-0003-0723-9447
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Research Areas
  • Acute Ischemic Stroke Management
  • Inflammatory Biomarkers in Disease Prognosis
  • Glioma Diagnosis and Treatment
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Neurogenesis and neuroplasticity mechanisms
  • Lipoproteins and Cardiovascular Health
  • Kruppel-like factors research
  • Autoimmune and Inflammatory Disorders Research
  • Brain Metastases and Treatment
  • Cerebrovascular and Carotid Artery Diseases
  • Ocular Oncology and Treatments
  • Vasculitis and related conditions
  • RNA Interference and Gene Delivery
  • Lysosomal Storage Disorders Research
  • Optical Imaging and Spectroscopy Techniques
  • Extracellular vesicles in disease
  • Peripheral Neuropathies and Disorders
  • Spinal Cord Injury Research
  • Neurological Disease Mechanisms and Treatments
  • Multiple Sclerosis Research Studies
  • Meningioma and schwannoma management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Ocular Diseases and Behçet’s Syndrome
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Urological Disorders and Treatments

First Affiliated Hospital of Shantou University Medical College
2010-2024

Shantou University
2012-2024

BackgroundMicroplastic (MP) pollution has emerged as a significant environmental concern worldwide. While extensive research focused on their presence in marine organisms and ecosystems, potential impact human health, particularly the circulatory system, remains understudied. This project aimed to identify quantify mass concentrations, polymer types, physical properties of MPs thrombi surgically retrieved from both arterial venous systems at three anatomically distinct sites, namely,...

10.1016/j.ebiom.2024.105118 article EN cc-by-nc-nd EBioMedicine 2024-04-13

Stroke has been found to be highly correlated with the triglyceride-glucose (TyG) index. The relation between TyG index changes and stroke, however, seldom reported, current researches mentioning concentrate on individual values. We aimed investigate whether level change of was associated incidence stroke.Sociodemographic, medical background, anthropometric laboratory information were retrospectively collected. Classification conducted using k-means clustering analysis. Logistic regressions...

10.1186/s12933-023-01870-z article EN cc-by Cardiovascular Diabetology 2023-06-09

Anaplastic oligodendroglioma is a rare disease with an inadequately understood prognosis. The aim of this study was to investigate factors associated survival outcome in anaplastic patients. A population-based cohort conducted based on the Surveillance, Epidemiology, and End Results program. In total, 1899 patients histological diagnosis from 1973 2015 were included. Mean age at 49.2 years, 56.19% male. our study, 62.40% married, 87.05% white. Most (90.42%) diagnosed as their first malignant...

10.1371/journal.pone.0211513 article EN cc-by PLoS ONE 2019-01-30

Background: Diffuse astrocytoma (DA) is a rare disease with inadequately understood epidemiological characteristics and prognosis. Identification of the factors associated survival in DA patients therefore necessary. In this study, we aim to investigate clinicopathological delineate influencing DA. Methods: A population-based cohort study was conducted, utilizing prospectively extracted data from Surveillance, Epidemiology End Results (SEER) database. Patients histological diagnosis SEER...

10.3389/fsurg.2021.712350 article EN cc-by Frontiers in Surgery 2021-10-15

Objective To investigate the correlation between serum lipoprotein (a) (Lp(a)) level and ischemic stroke its etiological subtypes. Methods The consecutive inpatients with acute (case group) age-and sex-matched healthy subjects (control over same period were enrolled retrospectively. The demographic baseline clinical data, as well fasting blood glucose, fibrinogen, homocysteine, total cholesterol, triacylglycerol, high-density low-density Lp(a) concentration of case group control...

10.3760/cma.j.issn.1673-4165.2016.12.002 article EN Int J Cerebrovasc Dis 2016-12-28
Andrew F. Siegel Cristina Palmer Corinne Atty Marin Sekosan Courtney M.P. Hollowell and 95 more Mark Wille Murat Tuncer Banu Erdogan Özgür Yazıcı Cahit Şahin Gökhan Altın Gökhan Faydacı Bilal Eryıldırım Kemal Sarıca Stavros Sfoungaristos Adamantios Kavouras Panagiotis Kanatas Mordechai Duvdevani Petros Perimenis Mohamed A. Elkoushy Alice L. Yu Roger Tabah Richard Payne Alice Dragomir Sero Andonian Jae H. Kim Whan Doo Jae Yang Yun Seong Song Jiyoung Hwang Seong‐Tshool Hong Soon-Sun Kwon R. Multescu B. Geavlete D. Georgescu P. Geavlete Matthew J. Maurice Edward E. Cherullo Robert I. Carey Christopher Martin Jacob Knego Female Yukio Homma Tetsuya Fujimura Hongde Chen Feng Wang Wei Chen Ting Ye Qi Zhou Feng Shao Shengjie Dai Zhixian Yu Yirong Zhang Chengdi Li Bicheng Chen Zhiliang Weng Philip Hanno Anne M. Suskind Rodney L. Dunn Yun Zhang John M. Hollingsworth Brent K. Hollenbeck Archie Hughes‐Hallett Philip Pratt Erik Mayer Shirley Martin Kieran J. Breen Paul Sweeney Patrick Nicholson Eamonn A. Kiely M.F. O’Brien Richard A. Santucci Charles S. Modlin Joan M. Alster Ismail Saad Yee Tiong Barbara Mastroianni Kathy Savas Carlumandarlo E.B. Zaramo Hannah Kerr David A. Goldfarb Stuart M. Flechner Raja B. Khauli Gwen M. Grimsby Paul Andrews Erik P. Castle Rafael N. Nuñez Laurie Mihalik Yu‐Hui Chang Mitchell R. Humphreys Seyyed Mohammad Kazem Aghamir Alborz Salavati Reza Yousefie Zahra Tootian Noushin Ghazaleh Mostafa Jamali Pourya Azimi Qiaoxin Zhang Yingxiu Xiao Weiduan Zhuang

10.1016/s0090-4295(14)00521-4 article EN Urology 2014-06-26

Objective To investigate the imbalance of T helper 17 (Th17) / CD4 + CD25 regulatory cell (Treg) in HAM/TSP patients.Methods Enzyme linked immunosorbent assay (ELISA) was performed to measure levels interleukin (IL-17) and IL-10 CSF,and flow cytometry determine percentage Th17 Treg cells peripheral blood patients with HAM/TSP.Results There a significant increase level IL-17 [(4.58 ± 0.70)pg/ml vs (0.76 0.17)pg/ml,P < 0.01] CSF [(2.00 0.64) % (0.41 0.24) %,P 0.01],but decrease compared...

10.3760/cma.j.issn.1008-1372.2013.01.006 article EN 中国医师杂志 2013-01-20

Objective To study the clinical and imaging feature of primary angiitis central nervous system(PACNS),in order to find key point diagnosis.Materials Methods Pathological or proved PACNS 9 cases,3 men 5 women,ranging from 19~73 years old with average 40.2 old.All were examined MRI 4 by enhanced scan:8 MRA 2 DSA.Clinical information all films(MRI DSA)were analyzed.Results In 8 cases PACNS,1cases operation biopsy,and 7 follow-up.8 located supratentorial,most in frontal lobe,3 multiple focuses...

10.3760/cma.j.issn1673-8799.2009.12.49 article EN Zhongguo linchuang shiyong yixue 2009-12-25

Objective To evaluate the predicting value of marker endothelial injury: plasma matrix metalloproteinase-9( MMP-9) and high sensitivity C-reactive protein( hsCRP) level on progression acute anterior circulating territory infarction progressing to malignant middle cerebral artery (m-MCAI). Methods 90 patients with infarction, in which 46 progressed m-MCAI, were collected sampled consecutively. The MMP-9 hsCRP all determined by ELISA immunotur-bidimetry,respectively,at admission. And clinical...

10.3760/cma.j.issn.1008-6706.2010.10.004 article EN Zhongguo jiceng yiyao 2010-05-15

Background: The neutrophil-lymphocyte ratio (NLR) is increasingly known as an indicator of systemic inflammation. It used a predictor for clinical outcomes in cancers and cardiovascular disease. However, its relationship with intracerebral hemorrhage (ICH) still disputed. Aims: We sought to evaluate the association between NLR ICH this meta-analysis. Methods: Potentially relevant articles were searched PubMed, Cochrane Library, Medline EMBASE until April 8, 2018, English restriction....

10.17504/protocols.io.qzvdx66 preprint EN 2018-06-15

Background: The neutrophil-lymphocyte ratio (NLR) is increasingly known as an indicator of systemic inflammation. It used a predictor for clinical outcomes in cancers and cardiovascular disease. However, its relationship with intracerebral hemorrhage (ICH) still disputed. Aims: We sought to evaluate the association between NLR ICH this meta-analysis. Methods: Potentially relevant articles were searched PubMed, Cochrane Library, Medline EMBASE until April 8, 2018, English restriction....

10.17504/protocols.io.qzwdx7e preprint EN 2018-06-15

Background Anaplastic oligodendroglioma (AO) is a rare disease with inadequately understood prognosis. The aim of this study to investigate factors associated survival outcome in AO patients. Methods A population-based cohort was conducted based on the Surveillance, Epidemiology, and End Results (SEER) program. Patients histological diagnosis from 1973 2015 were included. 1899 patients included our study. Mean age 49.2 years 56.19% male. 62.40% married 87.05% white. Most (90.42%) diagnosed...

10.17504/protocols.io.wmifc4e preprint EN 2018-12-24
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