Dhirendra Kumar Singh

ORCID: 0000-0003-0754-9293
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About
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Research Areas
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Vector-borne infectious diseases
  • Infant Nutrition and Health
  • Parasites and Host Interactions
  • Zoonotic diseases and public health
  • Neonatal Respiratory Health Research
  • Parasite Biology and Host Interactions
  • Viral gastroenteritis research and epidemiology
  • Helminth infection and control
  • Salmonella and Campylobacter epidemiology
  • Antifungal resistance and susceptibility
  • Brucella: diagnosis, epidemiology, treatment
  • Gut microbiota and health
  • SARS-CoV-2 and COVID-19 Research
  • Nitrogen and Sulfur Effects on Brassica
  • Escherichia coli research studies
  • Viral Infections and Outbreaks Research
  • Fungal Infections and Studies
  • Yersinia bacterium, plague, ectoparasites research
  • Peptidase Inhibition and Analysis
  • Monoclonal and Polyclonal Antibodies Research
  • Clinical Nutrition and Gastroenterology
  • Bartonella species infections research
  • Hepatitis Viruses Studies and Epidemiology

Maharishi Markandeshwar University, Mullana
2024

University of North Carolina at Chapel Hill
2023-2024

Umeå University
2023-2024

Indian Veterinary Research Institute
2004-2023

University of Szeged
2016-2022

Medanta The Medicity
2021

Okinawa University
2017

University of Delhi
2016

Abstract Beneficial gut bacteria are indispensable for developing colonic mucus and fully establishing its protective function against intestinal microorganisms. Low-fiber diet consumption alters the bacterial configuration disturbs this microbe-mucus interaction, but specific microbial metabolites responsible maintaining remain poorly understood. By using human-to-mouse microbiota transplantation ex vivo analysis of function, we here show as a proof-of-concept that individuals who increase...

10.1038/s41467-024-47594-w article EN cc-by Nature Communications 2024-04-25

Vulvovaginal candidiasis (VVC) is a common clinical condition with symptoms and signs of vaginal inflammation in the presence Candida species. At least one episode VVC experienced up to 75% women reproductive age group during their lifetime, 5% 8% such suffer from chronic form. Most cases are still caused by C. albicans. However, incidence non-albicans (NAC) species, as parapsilosis, continuously increasing. Despite prevalence NAC, little known about these species almost nothing mechanisms...

10.1128/spectrum.02696-21 article EN Microbiology Spectrum 2022-05-02

The fungal cell wall contains glycoproteins that interact with the host immune system. In prominent pathogenic yeast Candida albicans, Pmr1 acts as a Golgi-resident ion pump provides cofactors to mannosyltransferases, regulating synthesis of mannans attached glycoproteins. To gain insight into putative conservation such crucial process within opportunistic yeasts, we were particularly interested in studying role PMR1 homolog low-virulent species rarely causes candidiasis, guilliermondii. We...

10.3389/fmicb.2016.01951 article EN cc-by Frontiers in Microbiology 2016-12-02

Aspartyl proteases are present in various organisms and, among virulent species, considered major virulence factors. Host tissue and cell damage, hijacking of immune responses, hiding from innate cells the most common behaviors fungal secreted enabling pathogen survival invasion. C. parapsilosis , an opportunistic human-pathogenic fungus mainly threatening low-birth weight neonates children, possesses three SAPP protein-encoding genes that could contribute to invasiveness species. Our...

10.1128/msphere.00484-19 article EN cc-by mSphere 2019-08-20

It has become extremely difficult to guarantee the availability of safe food an ever-growing population due declining land resources, rising residual toxicity load, and water levels for agriculture drinking. Besides, it maintainsustainable production productivity using conventional agricultural system. In this context, thehydroponic system been a potential widely accepted technology confront above issues. addition ensuring food, hydroponics also maximizes vertical space utilization, improves...

10.21276/aatccreview.2025.13.01.127 article EN 2025-02-02

We experimentally study steady Marangoni-driven surfactant transport on the interface of a deep water layer. Using hydrodynamic measurements, and without using any knowledge physico-chemical properties, we show that sodium dodecyl sulphate Tergitol 15-S-9 introduced in low concentrations result flow driven by adsorbed surfactant. At higher concentration, is dominated dissolved Camphoric acid, whose properties are {\it priori} unknown, demonstrate this method's efficacy showing its spreading...

10.1103/physrevlett.119.264501 article EN cc-by Physical Review Letters 2017-12-28

Abstract Epigenetic modifications, such as DNA methylation, are enzymatically regulated processes that directly impact gene expression patterns. In early life, they central to developmental programming and have also been implicated in regulating inflammatory responses. Research into the role of epigenetics neonatal health is limited, but there a growing body literature related methylation patterns diseases prematurity, intestinal disease necrotizing enterocolitis (NEC). NEC severe disease,...

10.1017/erm.2024.16 article EN cc-by-nc-nd Expert Reviews in Molecular Medicine 2024-01-01
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