Chris Grasso
A5022682386- HIV/AIDS Research and Interventions
- LGBTQ Health, Identity, and Policy
- HIV, Drug Use, Sexual Risk
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- Reproductive Health and Technologies
- HIV Research and Treatment
- Sexuality, Behavior, and Technology
- Sex work and related issues
- Gender Roles and Identity Studies
- African Sexualities and LGBTQ+ Issues
- Sex and Gender in Healthcare
- Viral-associated cancers and disorders
- Adolescent Sexual and Reproductive Health
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Marine and coastal plant biology
- Food Security and Health in Diverse Populations
- Smoking Behavior and Cessation
- Acne and Rosacea Treatments and Effects
- Coral and Marine Ecosystems Studies
- Primary Care and Health Outcomes
- Healthcare Policy and Management
Fenway Health
2016-2025
Massachusetts General Hospital
2013-2023
Beth Israel Deaconess Medical Center
2023
Harvard University
2013-2023
University of Delaware
2019-2021
University of California, San Diego
2019-2020
Northeastern University
2020
U.S. Army Engineer Research and Development Center
2020
United States Army
2020
United States Army Corps of Engineers
2020
The Institute of Medicine and Joint Commission have recommended asking sexual orientation gender identity (SOGI) questions in clinical settings including such data Electronic Health Records (EHRs). This is increasingly viewed as a critical step toward systematically documenting addressing health disparities affecting lesbian, gay, bisexual, transgender (LGBT) people. U.S. government currently considering whether to include SOGI collection the Stage 3 guidelines for incentive program...
The purpose of this study was to better understand substance use behaviors and deleterious health consequences among individuals with HIV.We examined a multicenter cohort HIV-infected patients (n = 3,413) receiving care in 4 US cities (Seattle, Birmingham, San Diego, Boston) between December 2005 April 2010 the Centers for AIDS Research Network Integrated Clinical Systems (CNICS). We used generalized estimating equations model specific outcomes.Overall, 24% reported recent marijuana; 9%...
This report describes the evolution of a Boston community health center's multidisciplinary model transgender healthcare, research, education, and dissemination best practices. process began with development community-based approach to care that has been refined over almost 20 years where patients have received tailored services through Transgender Health Program. The program as response unmet clinical needs grown recognition our local culturally responsive links biobehavioral training,...
Background. Human immunodeficiency virus (HIV)-infected adults, particularly those of black race, are at high-risk for end-stage renal disease (ESRD), but contributing factors evolving. We hypothesized that improvements in HIV treatment have led to declines risk ESRD, among HIV-infected blacks. Methods. Using data from the North American AIDS Cohort Collaboration Research and Design January 2000 December 2009, we validated 286 incident ESRD cases using abstracted medical evidence dialysis...
Age-associated conditions are increasingly common among persons living with human immunodeficiency virus (HIV) (PLWH). A longitudinal investigation of their accrual is needed given implications on clinical care complexity. We examined trends in the co-occurrence age-associated PLWH receiving care, and differences prevalence by demographic subgroup.
Abstract High sea surface temperatures often lead to coral bleaching wherein reef-building corals lose significant numbers of their endosymbiotic dinoflagellates (Symbiodiniaceae). These increasingly frequent events result in large scale mortality, thereby devasting reef systems throughout the world. The habitats surrounding Palau are ideal for investigating responses climate perturbation, where many inshore bays subject higher water temperature as compared with offshore barrier reefs. We...
Abstract Lesbian, gay, bisexual, transgender, and queer (LGBTQ) people experience significant health disparities across the life course require care that addresses their unique needs. Collecting information on sexual orientation gender identity (SO/GI) of patients entering SO/GI data in electronic records has been recommended by Institute Medicine, Joint Commission, Health Resources Services Administration as fundamental to improving access quality for LGBTQ people. Most healthcare...
Abstract Background. Human immunodeficiency virus (HIV)–infected patients coinfected with hepatitis B (HBV) and C (HCV) viruses are at increased risk of end-stage liver disease (ESLD). Whether modern antiretroviral therapy has reduced ESLD is unknown. Methods. Twelve clinical cohorts in the United States Canada participating North American AIDS Cohort Collaboration on Research Design validated events from 1996 to 2010. incidence rates rate ratios according status adjusted for age, sex, race,...
Abstract Introduction Discontinuations of HIV preexposure prophylaxis (Pr EP ) by at‐risk individuals could decrease the effectiveness Pr . Our objective was to characterize patterns of, reasons for, and clinical outcomes associated with discontinuations in primary care. Methods We conducted medical chart reviews for patients prescribed during 2011 2014 at a Boston community health centre specializing healthcare sexual gender minorities. Patients were followed through 2015. characterized...
Objectives. To assess the performance of US health centers during first year required sexual orientation and gender identity (SOGI) data reporting to estimate baseline proportion lesbian, gay, bisexual, transgender patients accessing centers. Methods. We conducted a secondary analysis SOGI from 2016. These were reported by 1367 caring for 25 860 296 in United States territories. Results. missing 77.1% 62.8% patients, respectively. Among with data, 3.7% identified as or something else; 0.4%...
This study examined the association of appointment nonadherence to markers disease severity using one year demographic and health information on 995 individuals with HIV in primary care at an urban community centre. At latest visit, 106 946 valid cases (11.2%) had a CD4 less than or equal 200, 454 936 (48.5%) detectable plasma RNA (greater 50 copies/ml). Using logistic regression, (number missed appointments) was significant predictor (p < .03) having AIDS-defining count over above effects...
Cancer remains an important cause of morbidity and mortality in people with human immunodeficiency virus (PWHIV) on effective antiretroviral therapy (ART). Estimates cancer-attributable can inform public health efforts.
We estimated US Department of Health and Human Services (DHHS)–approved human immunodeficiency virus (HIV) indicators. Among patients, 71% were retained in care, 82% prescribed treatment, 78% had HIV RNA ≤200 copies/mL; younger adults, women, blacks, injection drug users poorer outcomes. Interventions are needed to reduce retention- treatment-related disparities.
Mental health disparities among transgender and gender diverse (TGD) populations have been documented. However, few studies assessed differences in mental symptom severity, substance use behavior engagement care across TGD subgroups. Using data from the electronic record of a community center specializing sexual minority health, we compared (1) severity self-reported depression, anxiety, alcohol use, other symptoms; (2) likelihood meeting clinical thresholds for these disorders; (3) number...
Abstract Reef‐building corals in the genus Porites are one of most important constituents Indo‐Pacific reefs. Many species within this tolerate abnormally warm water and exhibit high specificity for particular kinds endosymbiotic dinoflagellates that cope with thermal stress better than those living other corals. Still, during extreme ocean heating, some differences their tolerance. While have different physiological qualities, it remains unknown whether stability performance these...
Abstract Recent advances in electronic health records and information technology are providing new opportunities to improve the quality of care for transgender gender diverse people, a population that experiences significant disparities. This article recommends changes record systems have potential optimize gender-affirming care. Specifically, we discuss importance creating an anatomical inventory form captures organ diversity, developing clinical decision support tools management consider...
Antiretroviral drugs have been recommended for postexposure prophylaxis (PEP) after high-risk sexual exposures more than a decade. Three drug regimens could offer the highest levels of protection, particularly if infectious source is taking medication, but intolerance has often led to suboptimal adherence. The current study evaluated novel 3-drug PEP regimen, consisting raltegravir, tenofovir DF, and emtricitabine. Of 100 participants enrolled in this at Boston community health center that...
As the life expectancy of people infected with human immunodeficiency virus (HIV) infection has increased, spectrum illness evolved. We evaluated whether living HIV accessing primary care in US community health centers had higher morbidity compared HIV-uninfected patients receiving at same sites.We data from electronic records for 12 837 HIV-infected and 227 012 to evaluate relative prevalence diabetes mellitus, hypertension, chronic kidney disease, dyslipidemia, malignancies by serostatus....
The systematic documentation of sexual orientation and gender identity data in electronic health records can improve patient-centered care help to identify address disparities affecting minority populations. Although there are existing guidelines for among adult patients, not yet standard recommendations pediatric patients. In this article, we discuss methods that primary organizations use collect document information with children adolescents records. These take into consideration...
Background. The role of active hepatitis C virus (HCV) replication in chronic kidney disease (CKD) risk has not been clarified. Methods. We compared CKD incidence a large cohort HIV-infected subjects who were HCV seronegative, viremic (detectable RNA), or aviremic (HCV seropositive, undetectable RNA). Stages 3 and 5 defined according to standard criteria. Progressive was as sustained 25% glomerular filtration rate (GFR) decrease from baseline GFR < 60 mL/min/1.73 m2. used Cox models...
To determine whether HIV preexposure prophylaxis (PrEP) use is associated with of non-HIV-related health care.We conducted a cross-sectional study potential PrEP candidates at Boston, Massachusetts, community clinic during 2012 to 2016, comparing the proportion users and non-PrEP receiving primary care.Of 5857 candidates, 2047 (35%) were prescribed PrEP. After adjustment for demographics number visits, more received influenza vaccination (prevalence ratio [PR] = 1.28; 95% confidence interval...
Purpose: This study assessed disparities in screener- and provider-identified mental health substance use diagnoses treatment attendance by sexual orientation gender an urban community center focused on minority individuals. Methods: Using electronic data query (October 2015 to October 2018), computerized screening results assessing likely depression, anxiety, alcohol disorder (AUD), (SUDs); provider diagnoses; initiation related were compared across (heterosexual, gay/lesbian, bisexual,...