Elizabeth Humes
A5054796651- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV-related health complications and treatments
- LGBTQ Health, Identity, and Policy
- Sexuality, Behavior, and Technology
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Sex work and related issues
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Food Security and Health in Diverse Populations
- Syphilis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Homelessness and Social Issues
- Reproductive tract infections research
- COVID-19 Impact on Reproduction
- Herpesvirus Infections and Treatments
- Viral-associated cancers and disorders
- Intimate Partner and Family Violence
- Bartonella species infections research
- Machine Learning in Healthcare
- Hepatitis Viruses Studies and Epidemiology
- Chronic Disease Management Strategies
- Health and Lifestyle Studies
- Advanced Causal Inference Techniques
Johns Hopkins University
2019-2024
University of Colorado Anschutz Medical Campus
2021
University of Colorado Denver
2021
University of Colorado Hospital
2021
California State University, Long Beach
2020
Yale University
2015-2019
University of Washington
2019
University of Alabama at Birmingham
2019
Baltimore City Health Department
2017-2018
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2013
<h3>Importance</h3> Recommendations for additional doses of COVID-19 vaccines people with HIV (PWH) are restricted to those advanced disease or unsuppressed viral load. Understanding SARS-CoV-2 infection risk after vaccination among PWH is essential informing guidelines. <h3>Objective</h3> To estimate the rate and breakthrough infections fully vaccinated without (PWoH) in United States. <h3>Design, Setting, Participants</h3> This cohort study used Corona-Infectious-Virus Epidemiology Team...
Estimating the medical complexity of people aging with HIV can inform clinical programs and policy to meet future healthcare needs. The objective our study was forecast prevalence comorbidities multimorbidity among (PWH) using antiretroviral therapy (ART) in United States (US) through 2030.
Understanding how complex networks of genes integrate to produce dividing cells is an important goal that limited by the difficulty in defining function individual genes. Current resources for systematic identification gene such as siRNA libraries and collections deletion strains are costly organism specific. We describe here integration profiling, a novel approach identify eukaryotic based upon dense maps transposon integration. As proof concept, we used Hermes generate library 360,513...
Understanding advances in the care and treatment of adults with HIV as well remaining gaps requires comparing differences mortality between persons entering for general population.To assess extent to which among United States is elevated over matched U.S. population trends this difference time.Observational cohort study.Thirteen sites from North American AIDS Cohort Collaboration on Research Design.82 766 clinical 1999 2017 a subset calendar time, age, sex, race/ethnicity, county using data...
Understanding the severity of postvaccination SARS-CoV-2 (ie, COVID-19) breakthrough illness among people with HIV (PWH) can inform vaccine guidelines and risk-reduction recommendations.To estimate rate risk severe vaccinated PWH without (PWoH) who experience a infection.In this cohort study, Corona-Infectious-Virus Epidemiology Team (CIVET-II) collaboration included adults (aged ≥18 years) were receiving care fully by June 30, 2021, along PWoH matched according to date vaccinated, age...
Objective: To project the future age distribution of people with HIV using antiretroviral therapy (ART) in United States, under expected trends diagnosis and survival (baseline scenario) achieving ending epidemic (EHE) goals a 75% reduction diagnoses from 2020 to 2025 sustaining levels 2030 (EHE75% scenario). Design: An agent-based simulation model mathematical functions estimated North American AIDS Cohort Collaboration on Research Design data parameters US Centers for Disease Control...
Improvements in life expectancy among people living with human immunodeficiency virus (PLWH) receiving antiretroviral treatment the United States and Canada might differ key populations. Given difference substance use populations current opioid epidemic, drug- alcohol-related deaths be contributing to disparities expectancy. We sought estimate at age 20 years (and their comparison groups) 3 time periods (2004-2007, 2008-2011, 2012-2015) potential increase expected a simulated 20% reduction...
Foodborne pathogens cause >9 million illnesses annually. Food safety efforts address the entire food chain, but an essential strategy for preventing foodborne disease is educating consumers and preparers. To better understand epidemiology of to direct prevention efforts, we examined incidence Salmonella infection, Shiga toxin-producing Escherichia coli hemolytic uremic syndrome by census tract-level socioeconomic status (SES) in Connecticut Diseases Active Surveillance Network site...
The HIV epidemic disproportionately impacts transgender women in the United States. Cohort studies identify unique risks for affected populations, but use of facility-based methods may bias findings towards individuals living research catchment areas, more engaged health services, or, case those who are open about their identity. Digital clinical trials and other online increasingly common, providing opportunity to reach not commonly research. Simultaneously, there is a need understand...
The release of the first drug for human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) in 2012 marked beginning a new era HIV prevention. Although PrEP is highly efficacious, identifying and ultimately increasing uptake among highest risk male subgroups remains challenge. Public health surveillance data from 2009 to 2016 was used evaluate an diagnosis after syphilis (ie, primary, secondary, or early latent), gonorrhea, repeat diagnoses urban males, including men who have sex...
Abstract Background The updated Veterans Aging Cohort Study (VACS) Index 2.0 combines general and human immunodeficiency virus (HIV)–specific biomarkers to generate a continuous score that accurately discriminates risk of mortality in diverse cohorts persons with HIV (PWH), but alone is difficult interpret. Using data from the North American AIDS Collaboration (NA-ACCORD), we translate VACS scores into validated probability estimates mortality. Methods Because complete ascertainment...
Recommendations for additional doses of COVID vaccine are restricted to people with HIV who have advanced disease or unsuppressed viral load. Understanding SARS-CoV-2 infection risk post-vaccination among PWH is essential informing vaccination guidelines.
Background. The introductions of the varicella vaccine in 1995 and herpes zoster (HZ) 2006 have an ongoing potential to modify epidemiology both diseases. Analysis data on hospitalizations can be conducted examine trends occurrence severe disease over time assess possible impact vaccination incidence hospitalization. Methods. Statewide hospital discharge 1994-2012 Connecticut were used identify individuals discharged with a diagnosis initial admissions persons HZ first or second diagnostic...
This study characterized arrest, incarceration, and risk factors for incident incarceration among transgender women (TW) in the northeastern southern United States. During semiannual visits over 24 months a multicenter cohort study, TW completed HIV testing self-administered surveys. In total, 1571 baseline survey; 1,312 HIV-negative enrolled contributed 2134.3 person-years to analysis. At baseline, 37% had been arrested 21% incarcerated. Incident was 23.4 per 1,000 (95% confidence interval...
The age-distribution of men who have sex with (MSM) continues to change in the 'Treat-All' era as effective test-and-treat programs target key-populations. However, nature these changes and potential racial heterogeneities remain uncertain.
Background In the United States, transgender women are disproportionately impacted by HIV and prioritized in national strategy to end epidemic. Individual, interpersonal, structural vulnerabilities underlie acquisition among fuel syndemic conditions, yet no nationwide cohort monitors their other health outcomes. Objective Our objective is develop a estimate incidence, identify risk factors, investigate conditions co-occurring with vulnerability or US women. The study informed Syndemics...
Background People with HIV (PWH) are at an increased risk of cardiovascular disease (CVD) unknown added impact hepatitis C virus (HCV) coinfection. We aimed to identify whether HCV coinfection increases the type 1 myocardial infarction (T1MI) and if differs by age. Methods Results used data from NA-ACCORD (North American AIDS Cohort Collaboration on Research Design) January 1, 2000, December 31, 2017, PWH (aged 40-79 years) who had initiated antiretroviral therapy. The primary outcome was...
From 2005 to 2018, among 32013 adults with human immunodeficiency virus entering care, median time antiretroviral therapy (ART) prescription declined from 69 6 days, CD4 count at entry into care increased 300 362 cells/μL, and ART 160 364 cells/μL.