A5030482841- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- NMR spectroscopy and applications
- Atomic and Subatomic Physics Research
- Radiomics and Machine Learning in Medical Imaging
- Functional Brain Connectivity Studies
- Advanced NMR Techniques and Applications
- Bone and Joint Diseases
- Medical Imaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Fetal and Pediatric Neurological Disorders
- Lanthanide and Transition Metal Complexes
- Parkinson's Disease Mechanisms and Treatments
- Electron Spin Resonance Studies
- Advanced X-ray Imaging Techniques
- Photoacoustic and Ultrasonic Imaging
- Medical Image Segmentation Techniques
- Cardiovascular Health and Disease Prevention
- Obstructive Sleep Apnea Research
- Neonatal and fetal brain pathology
- Dementia and Cognitive Impairment Research
- Elasticity and Material Modeling
- Cerebral Palsy and Movement Disorders
- Cardiac Imaging and Diagnostics
University of Illinois Urbana-Champaign
2006-2025
University of Illinois Chicago
2016-2025
Resonance Research (United States)
2016-2025
Illinois College
2014-2024
Peking Union Medical College Hospital
2011-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2024
Affiliated Hospital of Qingdao University
2024
West China Second University Hospital of Sichuan University
2024
Sichuan University
2024
Qingdao University
2024
Whenever a linear gradient is activated, concomitant magnetic fields with non-linear spatial dependence result. This consequence of Maxwell's equations, i.e., within the imaging volume field must have zero divergence, and has negligible curl. The concomitant, or Maxwell been described in MRI literature for over 10 years. In this paper, we theoretically experimentally show existence two additional lowest-order terms field, which call cross-terms. cross-terms only arise when longitudinal Gz...
Background: In the midbrain of patients with Parkinson disease (PD), there is a selective loss dopaminergic neurons in ventrolateral and caudal substantia nigra (SN). mouse model PD, investigators have administered 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) found that measures derived using diffusion tensor imaging (DTI) were correlated number dopamine lost following intoxication.
In general, multiple components such as water direct saturation, magnetization transfer (MT), chemical exchange saturation (CEST) and aliphatic nuclear Overhauser effect (NOE) contribute to the Z ‐spectrum. The conventional CEST quantification method based on asymmetrical analysis may lead errors due semi‐solid MT asymmetry NOE located a single side of Fitting individual contributors ‐spectrum improve each component. this study, we aim characterize exchangeable from an intracranial tumor...
The purpose of the present study was to characterize association between clinical symptoms and anatomical functional cerebral deficits in a relatively large sample antipsychotic-naive first-episode schizophrenia patients using optimized voxel-based morphometry resting state connectivity analysis.Participants were 68 matched healthy comparison subjects. Both subjects scanned volumetric three-dimensional spoiled gradient recall sequence gradient-echo echo-planar imaging sequence....
<b>Objective:</b> To quantify the effects of traumatic brain injury on integrity thalamocortical projection fibers and to evaluate whether damage these accounts for impairments in executive function chronic injury. <b>Methods:</b> High-resolution (voxel size: 0.78 mm × 3 mm<sup>3</sup>) diffusion tensor MRI thalamus was conducted 24 patients with a history single, closed-head (TBI) (12 each mild TBI moderate severe TBI) 12 age- education-matched controls. Detailed neuropsychological testing...
It is well known that diffusion-induced MR signal loss deviates from monoexponential decay, particularly at high b-values (e.g., >1500 sec/mm2 for human brain tissues). A number of models have been developed to describe this anomalous diffusion behavior and relate the measurements tissue structures. Recently, a new model was proposed by solving Bloch-Torrey equation using fractional order calculus with respect time space (Magin et al., J Magn Reson 2008;190:255-270; Zhou Proc Int'l Soc Med...
Lu LH, Zhou XJ, Keedy SK, Reilly JL, Sweeney JA. White matter microstructure in untreated first episode bipolar disorder with psychosis: comparison schizophrenia. Bipolar Disord 2011: 13: 604–613. © 2011 The Authors. Journal compilation John Wiley & Sons A/S. Objectives: abnormalities have been reported disorder. present study aimed to investigate white integrity patients psychotic using diffusion tensor imaging, and compare observations those from schizophrenia patients. Methods:...
ABSTRACT Diffusion tensor imaging could be useful in characterizing movement disorders because it noninvasively examines multiple brain regions simultaneously. We report a multitarget approach focused on the basal ganglia and cerebellum Parkinson's disease, parkinsonian variant of system atrophy, progressive supranuclear palsy, essential tremor healthy controls. Seventy‐two subjects were studied with diffusion protocol at 3 Tesla. Receiver operating characteristic analysis was performed to...
Purpose To demonstrate that a new set of parameters (D, β, and μ) from fractional order calculus (FROC) diffusion model can be used to improve the accuracy MR imaging for differentiating among low- high-grade pediatric brain tumors. Materials Methods The institutional review board performing hospital approved this study, written informed consent was obtained legal guardians patients. Multi-b-value diffusion-weighted magnetic resonance (MR) performed in 67 patients with Diffusion coefficient...
Abstract Healthy human brain undergoes significant changes during development. The developmental trajectory of superficial white matter (SWM) is less understood relative to cortical gray (GM) and deep matter. In this study, a multimodal imaging strategy was applied vertexwise map SWM microstructure thickness characterize their pattern elucidate SWM‐GM associations in children adolescents. Microscopic were evaluated with water diffusion parameters including fractional anisotropy (FA), mean...
Poststroke cognitive impairment is typified by prominent deficits in processing speed and executive function. However, the underlying neuroanatomical substrates of are not well understood, further elucidation needed. There may be utility fractionating functions to delineate neural substrates.One test amenable fine delineation Trail Making Test (TMT), which emphasizes (TMT-A) set shifting (TMT-B-A difference, proportion, quotient scores, TMT-B set-shifting errors). The TMT was administered 2...
Purpose To demonstrate that a continuous‐time random‐walk (CTRW) diffusion model can improve diagnostic accuracy of differentiating low‐ and high‐grade pediatric brain tumors. Methods Fifty‐four children with histopathologically confirmed tumors underwent MRI scans at 3Twith 12 b ‐values (0‐4000 s/mm 2 ). The imageswere fit to simplified CTRW extract anomalous coefficient, D m , temporal spatial heterogeneity parameters, α β respectively. Using histopathology results as reference, k ‐means...
Adipose tissue macrophage (ATM) infiltration is a major pathway for obesity-induced insulin resistance but has not been studied as mechanism in PCOS.We tested whether polycystic ovary syndrome (PCOS) associated with increased ATM infiltration, especially of inflammatory subtype identified by the CD11c marker.We conducted case-control study at an academic medical center United States.Fourteen PCOS and 14 control women similar age body mass index (BMI) underwent gluteal fat biopsy. Markers...