O. N. Ray Bignall

ORCID: 0000-0003-0798-448X
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About
Contact & Profiles
Research Areas
  • Adolescent and Pediatric Healthcare
  • Childhood Cancer Survivors' Quality of Life
  • Acute Kidney Injury Research
  • Healthcare Policy and Management
  • Pediatric Urology and Nephrology Studies
  • Chronic Kidney Disease and Diabetes
  • Racial and Ethnic Identity Research
  • Neonatal Respiratory Health Research
  • Sepsis Diagnosis and Treatment
  • Dialysis and Renal Disease Management
  • Global Health Workforce Issues
  • Neonatal Health and Biochemistry
  • Diversity and Career in Medicine
  • Ethics and Legal Issues in Pediatric Healthcare
  • Child and Adolescent Health
  • Neonatal and fetal brain pathology
  • COVID-19 and Mental Health
  • Sodium Intake and Health
  • Emergency and Acute Care Studies
  • Family Dynamics and Relationships
  • Climate Change and Health Impacts
  • Medical Education and Admissions
  • Endoplasmic Reticulum Stress and Disease
  • Renal Diseases and Glomerulopathies
  • Blood Pressure and Hypertension Studies

Nationwide Children's Hospital
2020-2023

The Ohio State University
2020-2023

University Hospital and Clinics
2023

University Medical Center
2023

Yale University
2023

American Society of Nephrology
2022

Johns Hopkins University
2022

University of California, Los Angeles
2022

Cincinnati Children's Hospital Medical Center
2015-2020

Importance Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults is associated with poor short-term long-term outcomes. Guidance required to focus efforts related expansion of pediatric AKI knowledge. Objective To develop expert-driven specific recommendations on needed research, education, practice, advocacy. Evidence Review At the 26th Acute Disease Quality Initiative meeting conducted November 2021 by 47 multiprofessional international...

10.1001/jamanetworkopen.2022.29442 article EN cc-by-nc-nd JAMA Network Open 2022-09-30

Importance Kidney disease is common in infants admitted to the neonatal intensive care unit (NICU). Despite risk of chronic kidney (CKD) discharged from NICU, neither evidence- nor expert-based recommendations exist guide clinical after discharge. Objective To develop for stratification and health monitoring among discharge NICU. Evidence Review At National Institute Health–supported Consensus Workshop Address Health Neonatal Intensive Care Unit Graduates meeting conducted February 2024, a...

10.1001/jamanetworkopen.2024.35043 article EN cc-by-nc-nd JAMA Network Open 2024-09-13

A physician workforce that reflects the patient population is associated with improved outcomes and promotes health equity. Notwithstanding, racial ethnic disparities persist within US medical schools, making some individuals underrepresented in medicine (URM). We sought to increase percentage of URM residents who matched into our pediatric residency programs from a baseline 5% 35% achieve demographic parity patients. developed multifaceted approach using multiple iterative tests change,...

10.1542/peds.2021-050964 article EN PEDIATRICS 2021-12-14

Acute kidney injury (AKI) in children is associated with increased morbidity, reduced health-related quality of life, greater resource utilization, and higher mortality. Improvements the timeliness precision AKI diagnosis are needed. In this report, we highlight existing, novel, on-the-horizon diagnostic risk-stratification tools for pediatric AKI, outline opportunities integration into clinical practice. We also summarize pediatric-specific high-risk diagnoses exposures as well potential...

10.1007/s00467-023-06133-3 article EN cc-by Pediatric Nephrology 2023-09-05

The nephrology and critical care communities have seen an increase in studies exploring acute kidney injury (AKI) epidemiology children. As a result, we now know that AKI is highly prevalent critically ill neonates, children, young adults. Furthermore, children who develop experience greater morbidity higher mortality. Yet knowledge gaps still exist suggest more comprehensive understanding of will form the foundation for future efforts designed to improve outcomes. In particular, areas...

10.1007/s00467-023-06164-w article EN cc-by Pediatric Nephrology 2023-10-24

10.1007/s40746-018-0134-z article EN Current Treatment Options in Pediatrics 2018-06-14

Abstract Background In the past decade, there have been substantial advances in our understanding of pathobiology pediatric acute kidney injury (AKI). particular, animal models and studies focused on relationship between development, nephron number, health identified a number heterogeneous pathophysiologies underlying AKI. Despite this progress, gaps remain Methods During 26th Acute Disease Quality Initiative (ADQI) Consensus conference, multidisciplinary group experts discussed evidence...

10.1007/s00467-023-06154-y article EN cc-by Pediatric Nephrology 2023-10-04

Racism and sexism that manifest as microaggressions are commonly experienced by members of minoritized groups. These actions comments erode their subjects' vitality sense belonging. Individuals from groups often left in a quandary, weighing the potential benefits risks addressing comments. Placing burden to interrupt bias on our marginalized colleagues is unjust. In part, it inappropriate expect them dismantle system they did not create. It essential for individuals with privilege who...

10.1542/peds.2021-052758 article EN PEDIATRICS 2021-08-20

Acute liver injury (ALI) in children is a life-threatening event, and definitive etiology can be identified approximately 50% of cases. Neuroblastoma amplified sequence (NBAS) gene mutations have been associated with broad phenotypic spectrum this disease, ranging from recurrent episodes fever-induced injuries to multiorgan involvement, including frequent infections as well skeletal immunological abnormalities. Here, we describe an adolescent female confirmed compound heterozygous NBAS...

10.1159/000508784 article EN cc-by-nc Case Reports in Nephrology and Dialysis 2020-10-13

The inescapable reality is the American health care system rooted in a US society steeped systemic racism. In recent years, there has been an increased acknowledgment of how racism affected kidney disease and for our patients.12–3 Many these discussions seek to advance justice by focusing on interwoven systems that perpetuate inequitable (e.g., individual risks, societal factors, access outcome differences, beliefs professionals). Mohottige colleagues provide compelling review embedded...

10.1681/asn.2022040428 article EN Journal of the American Society of Nephrology 2022-06-29

"The function of education is to teach one think intensively and critically. Intelligence plus character—that the goal true education." (Rev. Dr. Martin Luther King, Jr.) To advance kidney health equity, it critical train care providers researchers in skills that are important achieving equity. accomplish this, we must first re-evaluate extent which antiracism, social justice centered nephrology education. Preparing a new generation thought leaders who understand roles structural racism...

10.1681/asn.2022040432 article EN Journal of the American Society of Nephrology 2022-09-09

10.1681/asn.20247a0z3vzw article EN Journal of the American Society of Nephrology 2024-10-01

PERSPECTIVE article Front. Pediatr., 26 October 2022Sec. Pediatric Nephrology Volume 10 - 2022 | https://doi.org/10.3389/fped.2022.963811

10.3389/fped.2022.963811 article EN cc-by Frontiers in Pediatrics 2022-10-26
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