A5068358573- Dermatology and Skin Diseases
- Sympathectomy and Hyperhidrosis Treatments
- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Botulinum Toxin and Related Neurological Disorders
- Urticaria and Related Conditions
- Dermatological and COVID-19 studies
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- SARS-CoV-2 and COVID-19 Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Infection Control and Ventilation
- COVID-19 and healthcare impacts
- Drug-Induced Adverse Reactions
- COVID-19 Clinical Research Studies
- Hidradenitis Suppurativa and Treatments
- Dermatologic Treatments and Research
- RNA regulation and disease
- Nietzsche, Schopenhauer, and Hegel
- Glycogen Storage Diseases and Myoclonus
- Spondyloarthritis Studies and Treatments
- Natural Compound Pharmacology Studies
- Skin and Cellular Biology Research
- Skin Protection and Aging
Marche Polytechnic University
2015-2024
Andreas Sygros Hospital
2021-2022
National and Kapodistrian University of Athens
2022
University of Milan
2019
Ljubljana University Medical Centre
2014
University of Ljubljana
2014
Children's Clinical University Hospital
2014
Chronic spontaneous urticaria (CSU) is defined as occurrence of wheals and/or angioedema for ≥6 weeks. Omalizumab a monoclonal anti-IgE antibody effective in refractory CSU, but its mechanism action and markers predictive response remain not completely defined.To correlate baseline levels two proposed biomarkers, total IgE (bIgE) d-dimer (bd-dimer), clinical parameters to omalizumab relapses after drug withdrawal.In this retrospective Italian multicentre study, data were collected 470 CSU...
Abstract Background Eyelid dermatitis is a frequent reason of dermatological consultation. Its aetiology not univocal, being contact dermatitis, both allergic and irritant, the most frequent. The primary sources allergen exposure include cosmetics, metals, topical medications, from direct, indirect, or airborne contact. Objectives To define frequency positive patch test reactions to SIDAPA baseline series allergens, document precise final diagnosis in patients with eyelid involvement....
Atopic dermatitis (AD) therapeutic approach calls for a long-term treatment. Treatment options AD have recently undergone revolutionary change by the introduction of first biologic drug. Availability in daily practice last version international guidelines, taking peculiarities country into account, can contribute to good clinical Italy. To adapt European Dermatology Forum (EDF) guidelines Italian medical–legal context, EDF were assessed independently two independent renowned experts field...
The aim of this study is to assess the associations between chronic spontaneous urticaria (CSU), Helicobacter pylori infection and small intestinal bacterial overgrowth. Forty- eight patients with CSU were studied by scoring activity assesing quality life. Patients H. (n=11) or overgrowth (n=13) specifically treated for one week clinically evaluated both before 4 weeks after eradication therapy. Eradication led a significant improvement in (p<0.002). In contrast, was not associated any...
Angiogenesis plays a key role in the pathogenesis of psoriasis. New blood vessel formation occurs early during plaque lesion development psoriatic skin, and sometimes precedes disease recurrence. TNF-α, well established mediator inflammation psoriasis, up-regulates transcription several pro-angiogenic chemokines that are over-expressed skin serum, promoting microvascular modifications plaque. Adalimumab is fully human monoclonal antibody blocks interaction between TNF-α its cell surface...
Hidradenitis suppurativa is a chronic skin disease with an intense inflammatory activation. It typically affects the intertriginous areas cysts, fistulae, and scarring extremely painful. Patients suffer from severe psychological impact. HS still results in high unmet medical need several underdiagnosed cases, probably due to incomplete knowledge of pathogenesis HS. The use botulinum toxin has recently been proposed as effective therapy for
Chronic spontaneous urticaria might affect elderly patients, causing a serious impairment of their quality life. The therapeutic management the patient is challenging; in fact, first-line recommended therapy for symptom control are antihistamines, that may have interactions or increased risk side effects patients with comorbidities and poly-pharmacological regimen. Omalizumab first biological drug approved chronic resistant to antihistamines. Real-life data focusing on >65-year-old treated...
Abstract Background Actinic keratosis ( AK ) is a cutaneous intraepithelial neoplasm that typically develops on sun‐damaged skin. The incidence of increasing worldwide, and it accepted as the most frequent pre‐malignant lesion in humans. Objectives To demonstrate ingenol mebutate gel effective treatment actinic keratoses because its clinical, dermoscopic, capillaroscopic, histopathological immunohistochemical outcomes. Methods Sixty individuals with multiple non‐hypertrophic s were enrolled...