A5055523859- Reading and Literacy Development
- Neurobiology of Language and Bilingualism
- Language Development and Disorders
- Cognitive and developmental aspects of mathematical skills
- Functional Brain Connectivity Studies
- Neonatal and fetal brain pathology
- Action Observation and Synchronization
- EEG and Brain-Computer Interfaces
- Infant Development and Preterm Care
- Language, Metaphor, and Cognition
- Neuroscience and Music Perception
- Prenatal Substance Exposure Effects
- Advanced Neuroimaging Techniques and Applications
- Early Childhood Education and Development
- Child and Adolescent Psychosocial and Emotional Development
- Child Abuse and Trauma
- Neuroscience, Education and Cognitive Function
- Child Development and Digital Technology
- Diverse Music Education Insights
- Neonatal Health and Biochemistry
- Neural and Behavioral Psychology Studies
- Educational and Psychological Assessments
- Second Language Acquisition and Learning
- Anesthesia and Neurotoxicity Research
- Cognitive Abilities and Testing
Beijing Normal University
2020-2025
Boston Children's Hospital
2016-2022
Chinese Institute for Brain Research
2022
Harvard University
2016-2021
Boston Children's Museum
2018
University of Hong Kong
2011-2013
State Key Laboratory of Cognitive Neuroscience and Learning
2010
Abstract Numerous studies have shown that phonological skills are critical for successful reading acquisition. However, how the brain network supporting processing evolves and it supports initial course of learning to read is largely unknown. Here, first time, we characterized emergence in 28 children over three stages (prereading, beginning reading, emergent reading) longitudinally. Across these time points, decreases neural activation left inferior parietal cortex (LIPC) were observed...
Abstract Recent efforts have focused on screening methods to identify children at risk for dyslexia as early preschool/kindergarten. Unfortunately, while low sensitivity leads under‐identification of at‐risk children, specificity can lead over‐identification, resulting in inaccurate allocation limited educational resources. The present study identified kindergarten who do not subsequently develop poor reading skills specify factors associated with better outcomes among children. Early was...
Language acquisition is of central importance to child development. Although this developmental trajectory shaped by experience postnatally, the neural basis for language emerges prenatally. Thus, a fundamental question remains: do structural foundations in infancy predict long-term abilities? Longitudinal investigation 40 children from kindergarten reveals that white matter prospectively associated with subsequent abilities, specifically between: (i) left arcuate fasciculus and phonological...
Abstract Developmental dyslexia is a specific learning disability characterized by deficits reading single words. Dyslexia heritable and has been associated with neural alterations in regions of the left hemisphere brain. Cognitive atypicalities have observed before children familial risk for begin reading, yet who are at subsequently develop abilities on continuum from good to poor. Of those skills, what factors more successful outcomes? In this article, we review findings describing...
Abstract Childhood poverty has been associated with structural and functional alterations in the developing brain. However, does not alter brain development directly, but acts through biological or psychosocial risk factors (e.g. malnutrition, family conflict). Yet few studies have investigated context of infant neurodevelopment, none done so low‐resource settings such as Bangladesh, where children are exposed to multiple, severe hazards. In this feasibility pilot study, usable resting‐state...
Abstract Functional connectivity (FC) techniques can delineate brain organization as early infancy, enabling the characterization of characteristics associated with subsequent behavioral outcomes. Previous studies have identified specific functional networks in infant brains that underlie cognitive abilities and pathophysiology subsequently observed toddlers preschoolers. However, it is unknown whether how emerging within first 18 months life contribute to development higher order, complex...
Developmental dyslexia is a heritable learning disability affecting 7% to 10% of the general population and can have detrimental impacts on mental health vocational potential. Individuals with show altered functional organization language reading neural networks; however, it remains unknown how early in life these network alterations might emerge.To determine whether emergence large-scale connectivity (FC) underlying long-term development infants familial history (FHD).This cohort study...
Developmental dyslexia affects 40-60% of children with a familial risk (FHD+) compared to general prevalence 5-10%. Despite the increased risk, about half FHD+ develop typical reading abilities (FHD+Typical). Yet underlying neural characteristics favorable outcomes in at-risk remain unknown. Utilizing retrospective, longitudinal approach, this study examined whether putative protective mechanisms can be observed FHD+Typical at prereading stage. Functional and structural brain were 47...
Phonological processing has been postulated as a core area of deficit among children with dyslexia. Reduced brain activation during phonological in dyslexia observed left-hemispheric temporoparietal regions. Musical training shown positive associations abilities, but the neural mechanisms underlying this relationship remain unspecified. The present research aims to distinguish correlates school-age typically developing musically trained children, untrained and utilizing fMRI. A whole-brain...
Reading fluency-the speed and accuracy of reading connected text-is foundational to educational success. The current longitudinal study investigates the neural correlates fluency development using a connected-text paradigm with an individualized presentation rate. Twenty-six children completed functional MRI task in 1st/2nd grade (time 1) again 1-2 years later 2). There was increase activation ventral occipito-temporal (vOT) cortex from time 1 2. This also associated improvements skills...
Reading acquisition is a prolonged learning process relying on language development starting in utero. Behavioral longitudinal studies reveal prospective associations between infant abilities and preschool/kindergarten phonological that relates to subsequent reading performance. While recent pediatric neuroimaging work has begun characterize the neural network underlying infants, how this scaffolds long-term remains unknown. We addressed question 7-year study from infancy school-age....
Parent-child language interaction in early childhood carries long-term implications for children's and reading development. Conversational interaction, particular, has been linked to white matter organization of neural pathways critical reading. However, shared book serves an important role as it exposes children sophisticated vocabulary syntax. Despite this, remains unclear whether also relates characteristics subserving If so, what extent do these environmentally associated changes relate...
This fMRI study aimed to identify the neural mechanisms underlying recognition of Chinese multi-character words by partialling out confounding effect reaction time (RT). For this purpose, a special type nonword—transposable nonword—was created reversing character orders real words. These nonwords were included in lexical decision task along with regular (non-transposable) and Through conjunction analysis on contrasts transposable versus nonwords, RT was eliminated, regions involved word...
Musical training has long been viewed as a model for experience-dependent brain plasticity. Reports of musical training-induced plasticity are largely based on cross-sectional studies comparing musicians to non-musicians, which cannot address whether itself is sufficient induce these neurobiological changes or pre-existing neuroarchitecture before predisposes children succeed in music. Here, longitudinal investigation from infancy school age (n = 25), we find structure that predicts...
This study examined whether the degree of complexity a grammatical component in language would impact on its representation brain through identifying neural correlates morpheme processing associated with nouns and verbs Chinese. In particular, Chinese nominal classifiers verbal aspect markers were investigated sentence completion task grammaticality judgment to look for converging evidence. The constitutes special case because it has no inflectional morphology per se larger classifier than...
Exposure to psychosocial adversity (PA) is associated with poor behavioral, physical, and mental health outcomes in adulthood. As these are related alterations developmental processes, growing evidence suggests that deficits executive functions-inhibitory control particular-may, part, explain this relationship. However, literature examining the development of inhibitory has been based on children higher resource environments, little known how low settings might exacerbate link between...