A5023400410- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Heart Rate Variability and Autonomic Control
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Heart Failure Treatment and Management
- Nerve injury and regeneration
- Cardiac Imaging and Diagnostics
- Non-Invasive Vital Sign Monitoring
- Cardiac Valve Diseases and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Blood Pressure and Hypertension Studies
- Ion channel regulation and function
- Electrolyte and hormonal disorders
- Vascular Procedures and Complications
- Central Venous Catheters and Hemodialysis
- ECG Monitoring and Analysis
- Obstructive Sleep Apnea Research
- Alcohol Consumption and Health Effects
- Sodium Intake and Health
- Mitochondrial Function and Pathology
- Pharmacological Effects and Toxicity Studies
Kanazawa University
2015-2025
Kanazawa University Hospital
2012-2024
Kanazawa Medical University
2018-2023
Indiana University School of Medicine
2018-2021
Indiana University – Purdue University Indianapolis
2019-2021
Indiana University
2018-2020
University School
2020
Toyama Prefectural Central Hospital
2015-2016
Abstract While autonomic dysregulation and repolarization abnormalities are observed in subarachnoid hemorrhage (SAH), their relationship remains unclear. We aimed to measure skin sympathetic nerve activity (SKNA), a novel method estimate stellate ganglion activity, investigate its association with electrocardiogram (ECG) alterations after SAH. recorded total of 179 SKNA data from SAH patients at three distinct phases compared them 20 controls. Compared control data, the acute phase (days...
BACKGROUND. Simultaneous noninvasively recorded skin sympathetic nerve activity (SKNA) and electrocardiogram (neuECG) can be used to estimate cardiac tone. We tested the hypothesis that large prolonged SKNA bursts are associated with temporal clustering arrhythmias.
Selenoprotein P (SeP), a liver-derived secretory protein, functions as selenium supply protein in the body. SeP has been reported to be associated with insulin resistance humans through serial analysis of gene expression. Recently, found inhibit vascular endothelial growth factor-stimulated cell proliferation human umbilical vein cells, and impair angiogenesis mouse hind limb model. In this study, role ischemia/reperfusion (I/R) injury investigated. knockout (KO) littermate wild-type (WT)...
Pulmonary vein isolation (PVI) is an established treatment for atrial fibrillation (AF). While it known to affect the autonomic nervous system, relationship between left (LA) remodeling and PVI-mediated neuromodulation remains unclear. We aimed assess neuromodulatory effects of PVI using skin sympathetic nerve activity (SKNA). SKNA was recorded one day before 2–3 days after in 28 paroxysmal AF (PAF) 33 persistent (PerAF) groups. Baseline low frequency high (LF/HF) ratio higher PAF group...
A recent randomized trial demonstrated that catheter ablation for atrial fibrillation (AF) in patients with heart failure reduced ejection fraction (EF) is associated a reduction death or failure. However, the effect of AF mid-range preserved EF unclear.
Anemia, a common comorbidity in older patients with heart failure (HF) and atrial fibrillation (AF), is associated an increased risk of adverse events. This study evaluated the prognostic effects longitudinal changes anemia status on clinical outcomes AF.
Abstract Background Anemia is a common comorbidity in older patients with heart failure (HF)1 and atrial fibrillation (AF)2, associated an increased risk of adverse events. This study evaluated the prognostic effects longitudinal changes anemia status on clinical outcomes AF, as limited data are available this aspect. Methods Results We prospectively 1,388 AF obtained from Hokuriku-Plus registry (1,010 men, 72.3±9.7 years) recorded incidence cardiovascular death (CVD), HF, thromboembolism,...
Background: Few studies in Japan have reported on follow-up data regarding the clinical course and risk factors for adverse outcomes elderly patients with non-valvular atrial fibrillation (NVAF), vs. younger patients, when considering competing of death. Methods Results: We prospectively studied 1,328 NVAF (965 men; mean [±SD] age 72.4±9.7 years) from Hokuriku-Plus AF Registry a median 5.0 years (interquartile range 3.5-5.3 evaluated incidence thromboembolism or major bleeding (age ≥75...
The prognostic effect of concomitant hypertrophic cardiomyopathy (HCM) on adverse events in patients with atrial fibrillation (AF) has not been evaluated a multicenter prospective cohort study Japan.
The impact of left atrial (LA) size on isolation area (ISA) using a 28-mm second-generation cryoballoon (CB) in the acute phase after pulmonary vein (PVI) and differences CB from contact force-guided radiofrequency (RF) ablation have not been fully investigated.We examined 85 consecutive patients (CB group, 35; RF 50) with drug-refractory paroxysmal fibrillation who underwent their first PVI procedure at two institutions. We evaluated ISA 3D-Merge computed tomography images (GE Healthcare,...
The arterial velocity pulse index (AVI) and pressure-volume (API) have been proposed as new stiffness indices that can be measured using an oscillometric cuff. Sympathetic nerve activity (SNA) contributes to via increasing vascular smooth muscle tone. However, the associations between SNA AVI or API are not understood. purpose of this study was evaluate relationships sympathetic (MSNA) in healthy individuals patients with hypertension (HT). Forty (40.1 ± 15.2 years, 8 females) (healthy...