- Mechanical Circulatory Support Devices
- Heart Failure Treatment and Management
- Wireless Body Area Networks
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Advanced Sensor and Energy Harvesting Materials
- Innovative Energy Harvesting Technologies
- Transplantation: Methods and Outcomes
- Ultrasonics and Acoustic Wave Propagation
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Tactile and Sensory Interactions
- Respiratory Support and Mechanisms
- Semiconductor Lasers and Optical Devices
- Antenna Design and Analysis
- Acute Myeloid Leukemia Research
- Energy Harvesting in Wireless Networks
- Cardiac Valve Diseases and Treatments
- Asthma and respiratory diseases
- IL-33, ST2, and ILC Pathways
- Dermatology and Skin Diseases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Helminth infection and control
- Molecular Communication and Nanonetworks
- Millimeter-Wave Propagation and Modeling
University of Ulsan
2004-2025
Asan Medical Center
2004-2025
Ulsan College
2004-2025
Korea University
2024
Yeungnam University Medical Center
2024
Hanseo University
2021
Pusan National University Yangsan Hospital
2017
Tokyo Institute of Technology
2014
Korea Research Institute of Standards and Science
2006-2012
Tohoku University
2012
BACKGROUND: The morbidity and mortality rates of patients with heart failure (HF) functional mitral regurgitation (MR) remain substantial despite guideline-directed medical therapy for HF. We evaluated the efficacy ertugliflozin reduction MR associated HF mild to moderately reduced ejection fraction. METHODS: EFFORT trial (Ertugliflozin Functional Mitral Regurgitation) was a multicenter, double-blind, randomized examine hypothesis that sodium-glucose cotransporter 2 inhibitor is effective...
This study sought to assess the relationship between serum concentrations of soluble ST2 (sST2) and B-type natriuretic peptide (BNP) investigate role sST2 as a prognosticator in patients hospitalized with acute heart failure (HF) renal insufficiency. was measured at admission discharge 66 decompensated HF insufficiency (estimated glomerular filtration rate [eGFR] < 90 mL/min/1.73 m(2)) using high sensitivity immunoassay. BNP sampled same time compared sST2. Demographical, biochemical,...
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> High-voltage analog circuits, including a novel high-voltage regulation scheme, are presented with emphasis on low supply voltage, power consumption, area overhead, and noise, which key design metrics for implementing NAND Flash memory in mobile handset. Regulated high voltage generation at is achieved optimized oscillator, charge pump, regulator circuits. We developed methodology pump to...
Methylmercury is an environmental pollutant that toxic to the central nervous system; however, molecular mechanisms underlying its toxicity remain unclear. increases expression of several chemokines in cerebellum mice treated with methylmercury. The present study analyzes mechanism methylmercury-induced chemokine using human 1321N1 astrocytes, and shows methylmercury CCL2 these cells. transcription factor NF-κB involved induction expression. increased level p65 subunit nuclei increase was...
We evaluated the benefit of left ventricular (LV) unloading using a percutaneous transseptal atrial (LA) drain catheter via femoral vein incorporated into ECMO venous circuit. This single-center retrospective observational study analyzed clinical outcomes LA venting group (N = 62) who underwent placement comparing with conventionally treated control an arterial pulse pressure below 10 mm Hg for at least 24 hours from December 2012 to August 2018. The weaning rate (61.3% vs. 38.7%, P .012)...
Background: Pleural effusions commonly occur in patients recovering from cardiac surgery; however, the impact on outcomes is not well characterized.The purpose of this study to characterize clinical surgery with pleural effusion. Methods:All undergoing between 2006 and 2019 at a tertiary care university hospital were included observational, cross-sectional analysis using propensity matching.Results: Of 11,037 that underwent during period, 6461 (58.5%) had no effusion (Group 0), 3322 (30.1%)...
This paper describes a design of tactile sensor, which can measure three components forces. The bio-mimetic alternative to human's finger, is composed 100 micro force sensors, and its size being 10 mm x mm. Each sensor has square membrane, capacity 0.3 N in the three-axis directions. On other hand, measuring method three-component signals without interference was suggested case four strain gages number minimum data lines. We have fabricated using flexible MEMS technology based on polymer material.
Background Extracorporeal membrane oxygenation (ECMO) has been associated with platelet dysfunction, but no markers of dysfunction during ECMO have identified. Methods We investigated the potential uses beta-thromboglobulin (beta-TG) and factor 4 (PF4) as activation induced by in vivo. Results 13 patients who received for acute respiratory failure were included. Generalized estimating equations used to examine associations between days on plasma levels beta-TG PF4 proinflammatory markers....
Kinam Shin, M.D., Won Chul Cho, Ph.D., Nara M.Sc., Hong Rae Kim, Min-Seok Cheol Hyun Chung, Sung-Ho Jung, Ph.D.. J Chest Surg -0001;0:. https://doi.org/10.5090/jcs.23.135
Chronic dermatitis is a disease with large unmet need for pharmacological improvement. Dermatitis conditions are maintained and exacerbated by various cytokine actions in the context of inflammation. Interleukin 6 signal transducer (Il6st), also known as glycoprotein 130 (Gp130), key component surface reception multitude cytokines transduction amplification their pro-inflammatory signals. We hypothesized accordingly that inhibition Il6st can alter pathology. Treatment SC-144 bazedoxifene,...
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to eventual heart transplantation (HT) is increasingly used worldwide. However, the effect of different VA-ECMO types on HT outcomes remains unclear.This was retrospective observational study 111 patients receiving and awaiting HT. We assessed 3 ECMO configuration groups: peripheral (n=76), central (n=12), conversion (n=23). Cox proportional hazards regression landmark analysis were conducted analyze in-hospital...
The US Food and Drug Administration (FDA) European Medicines Agency (EMA) approved empagliflozin for reducing cardiovascular mortality heart failure (HF) hospitalization in patients with both HF reduced ejection fraction (HFrEF) preserved (HFpEF). However, limited data are available on the generalizability of to clinical practice. Therefore, we evaluated real-world eligibility potential cost-effectiveness based a nationwide prospective registry.
This paper presents a high-performance flexible tactile sensor based on inorganic silicon electronics. We created 100 nm-thick semiconducting ribbons equally distributed with 1mm spacing and 8×8 arrays to sense the pressure distribution high-sensitivity repeatability. The organic rubber substrate was used as spring material achieve both of mechanical flexibility robustness. A thin copper layer deposited patterned top sensing create temperature layer. fabricated tested through series...
Purpose Autologous stem cell transplantation (ASCT) is increasingly used in patients with non-Hodgkin's lymphoma (NHL). Various clinical parameters-were evaluated to obtain significant predictors of the outcome following ASCT NHL. Materials and Methods Between April 1994 December 2003, was performed on 80 NHL at Asan Medical Center. Results Patients had various histological subtypes disease status. The two year progression free survival (PFS) overall for all were 34 31%, respectively. A...