A5066614481- Microbial Inactivation Methods
- Microfluidic and Bio-sensing Technologies
- Lipid Membrane Structure and Behavior
- Photoreceptor and optogenetics research
- Electrochemical Analysis and Applications
- Magnetic and Electromagnetic Effects
- Neuroscience and Neural Engineering
- Spectroscopy and Quantum Chemical Studies
- Ion channel regulation and function
- DNA and Nucleic Acid Chemistry
- Cholinesterase and Neurodegenerative Diseases
- Neuroscience and Neuropharmacology Research
- Mass Spectrometry Techniques and Applications
- Nicotinic Acetylcholine Receptors Study
- Electrochemical sensors and biosensors
- Transgenic Plants and Applications
- Advanced Chemical Sensor Technologies
- Receptor Mechanisms and Signaling
- Analytical Chemistry and Chromatography
- Computational Drug Discovery Methods
- Analytical Chemistry and Sensors
- Neurobiology and Insect Physiology Research
- RNA and protein synthesis mechanisms
- Molecular Sensors and Ion Detection
- Biofield Effects and Biophysics
Bielefeld University
2003-2018
University of Ljubljana
2008
University of Oslo
1998
University of Nottingham
1996
Federal Institute For Materials Research and Testing
1996
Case Western Reserve University
1996
Ruhr University Bochum
1987
Max Planck Institute of Biochemistry
1976-1985
Institute of Biophysics
1984
Institut Pasteur
1983
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligandsHans-Juergen Nolte, Terrone L. Rosenberry, and Eberhard NeumannCite this: Biochemistry 1980, 19, 16, 3705–3711Publication Date (Print):August 5, 1980Publication History Published online1 May 2002Published inissue 5 August...
Gene electrotransfer is gaining momentum as an efficient methodology for nonviral gene transfer. In skeletal muscle, data suggest that electric pulses play two roles: structurally permeabilizing the muscle fibers and electrophoretically supporting migration of DNA toward or across permeabilized membrane. To investigate this further, combinations short high-voltage (HV; hundreds V/cm) mainly electrophoretic long low-voltage (LV; tens were investigated in liver, tumor, skin rodent models. The...
Gene electrotransfer is gaining momentum as an efficient methodology for nonviral gene transfer. In skeletal muscle, data suggest that electric pulses play two roles: structurally permeabilizing the muscle fibers and electrophoretically supporting migration of DNA toward or across permeabilized membrane. To investigate this further, combinations short high-voltage (HV; hundreds V/cm) mainly electrophoretic long low-voltage (LV; tens were investigated in liver, tumor, skin rodent models. The...
Electric impulses are capable of inducing long-lived conformational changes in (metastable) biopolymers. Results experiments with poly(A).2 poly(U) and ribosomal RNA, which known to develop metastabilities, reported. A polarization mechanism is proposed explain the structural transitions observed biopolymers exposed impulses. In accordance this idea, applied electric field (of about 20 kV/cm decaying exponentially, a decay time 10 musec) induces large dipole moments by shifting ionic...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorataThierry Heidmann, Julius Bernhardt, Eberhard Neumann, Jean Pierre ChangeuxCite this: Biochemistry 1983, 22, 23, 5452–5459Publication Date (Print):November 8, 1983Publication History Published online1 May 2002Published inissue 8 November...
Interaction of Ca and acetylcholine (AcCh) ions with purified receptor (AcChR) from Torpedo californica Electrophorus electricus has been investigated in view these ions' role proposed bioelectricity. Spectrophotometric titration using murexide as an indicator ultrafiltration method 45Ca show that AcChR proteins have a high binding capacity for ions. Per macromolecule 260,000 daltons, up to 60 can be bound at least three dissociation constants. A linear inhibition AcCh by was observed the...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMalate dehydrogenase isolated from extremely halophilic bacteria of the Dead Sea. 1. Purification and molecular characterizationMoshe Mevarech, Henryk Eisenberg, Eberhard NeumannCite this: Biochemistry 1977, 16, 17, 3781–3785Publication Date (Print):August 23, 1977Publication History Published online1 May 2002Published inissue 23 August 1977https://doi.org/10.1021/bi00636a009Request reuse permissionsArticle Views265Altmetric-Citations71LEARN ABOUT...
Abstract The general foundations for a thermodynamic analysis of hysteresis phenomena in solutions and suspensions polyelectrolyte systems are presented using examples molecular biopolymers membranes. fundamental cybernetic significance metastable states physical interpretation life such as memory recording biological rhythms is discussed.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermodynamic investigation of the helix-coil transitions a polyribonucleotide systemEberhard Neumann and Theodor AckermannCite this: J. Phys. Chem. 1969, 73, 7, 2170–2178Publication Date (Print):July 1, 1969Publication History Published online1 May 2002Published inissue 1 July 1969https://pubs.acs.org/doi/10.1021/j100727a012https://doi.org/10.1021/j100727a012research-articleACS PublicationsRequest reuse permissionsArticle...
It is demonstrated that the monomeric and dimeric structures of nicotinic acetylcholine receptor Torpedo californica electric tissue, reconstituted in planar lipid bilayers, are functionally different. The native dimer D Mr 500,000 (heavy-form) exhibits a "single" channel conductance about twice as large monomer M 250,000 (light form). Under conditions where monomers aggregate, changes from level to dimers M2. conductances (D M2) seem result synchronous opening closing two channels dimer,...