A5082227920- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Aortic Disease and Treatment Approaches
- Infectious Aortic and Vascular Conditions
- Vascular anomalies and interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
- Electrospun Nanofibers in Biomedical Applications
- Renal and Vascular Pathologies
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Reconstructive Surgery and Microvascular Techniques
- Angiogenesis and VEGF in Cancer
- Coronary Interventions and Diagnostics
- Abdominal vascular conditions and treatments
- Cardiovascular Health and Disease Prevention
- Cardiac Structural Anomalies and Repair
- Blood Coagulation and Thrombosis Mechanisms
- Antiplatelet Therapy and Cardiovascular Diseases
- Thermoregulation and physiological responses
- Cardiac tumors and thrombi
Tokyo Medical University
2016-2025
Hokkaido Information University
2023-2025
Japanese Circulation Society
2023
Society for Vascular Surgery
2023
Tokyo Medical University Hospital
2012-2021
Hosei University
2012
Society of Interventional Radiology
2012
Tokyo Medical University Hachioji Medical Center
2010-2011
Fujita Health University
2004-2010
Uniformed Services University of the Health Sciences
1998-2009
Ephrin ligands and Eph receptors are signaling molecules that differentially expressed on arteries veins during development. We examined whether Eph-B4, a venous marker, Ephrin-B2, an arterial regulated vein graft adaptation in humans aged rats.Eph-B4 transcripts immunodetectable protein downregulated endothelial smooth muscle cells of patent grafts both rats, whereas Ephrin-B2 not strongly induced. Other markers identity, including dll4 notch-4, also induced rats. Because VEGF-A is upstream...
Eph-B4 determines mammalian venous differentiation in the embryo but is thought to be a quiescent marker of adult veins. We have previously shown that surgical transposition vein into arterial environment characterized by loss identity, as indicated Eph-B4, and intimal thickening. used mouse model graft implantation test hypothesis critical determinant wall thickness during postsurgical adaptation environment. show stimulation signaling, either via ligand or expression constitutively active...
The arteriovenous fistula (AVF) is the preferred method of dialysis access because its proven superior long-term outcomes.However, women havelower rates AVF patency andutilizationthan men.We used a novel mouseAVF model that recapitulates human maturation to determine whether there are differences in female and male mice.Aortocaval fistulas were created C57BL/6 mice (9-10 weeks). At days 0, 3, 7, 21, infrarenal inferior vena cava (IVC) aortic diameters flow velocity monitored by Doppler...
Our primary concern was the risk of overtreating elderly patients with endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm. We investigated association between age at time EVAR and all-cause mortality in Japan's aging population by stratifying into groups. Data from 175 who underwent elective 2012 to 2016 were analyzed. Patients categorized 3 groups: <75 years, 75-84 ≥85 based on healthy life expectancy average expectancy. Survival rates factors assessed across these patient...
Objective Endovascular aneurysm repair (EVAR) has become a preferred method for treating abdominal aortic aneurysms (AAA) due to its minimally invasive approach. However, identifying factors that influence long-term patient outcomes is crucial improving prognosis. This study investigates whether machine learning (ML)-based decision tree analysis (DTA) can predict survival (over 5 years postoperatively) by uncovering complex patterns in data. Methods We retrospectively analyzed data from 142...
Endovascular aneurysm repair (EVAR) is widely used to treat abdominal aortic aneurysms (AAAs), but mid-term survival remains a concern. This study aims develop machine learning-based random forest model predict 3-year after EVAR. A was trained using data from 176 EVAR patients, of whom 169 patients were retained for analysis, incorporating 23 preoperative and perioperative variables. Model performance evaluated 5-fold cross-validation. The achieved an area under the receiver-operating...
Background: Several cases of horseshoe kidney with anomalous inferior vena cava (IVC) have been described, but there no reports the incidence and variation IVC in patients kidneys detected using multidetector row computed tomography (MDCT). Methods Results: 105 were evaluated MDCT a variety venous anomalies identified 30 (28.6%). Anatomical variations renal vein 24 (22.9%), which was higher than reported general population. However, 6 (5.7%), expected to be found population: 1 pre-isthmic...
Abstract Tissue factor (TF), a transmembrane glycoprotein, initiates the extrinsic coagulation cascade. TF is known to play major role in mediating thrombosis and thrombotic episodes associated with progression of atherosclerosis. Macrophages at inflammatory sites, such as atherosclerotic lesions, release numerous cytokines that are capable modulating expression. This study examined oncostatin M (OSM), macrophage/ T-lymphocyte–restricted cytokine, expression vascular smooth muscle cells...
Carotid angioplasty is associated with adverse events in elderly patients; it unclear whether this related to an altered inflammatory axis. The carotid arteries of young (6 months) or aged (22-24 Fischer 344 rats were balloon injured. Aged had reduced lumen area (0.18 ± 0.03 vs 0.24 0.01 mm(2), p = .02) and increased neointimal thickening (0.15 0.04 0.08 .006). circulating monocytes (96 21 vs. 54 7; .002) as well numbers at the post-angioplasty site. sustained monocyte chemotactic protein-1...
Purpose: This study aimed to assess whether hangekobokuto (HKT) can prevent aspiration pneumonia in patients undergoing cardiovascular surgery.
Abstract Background Aortoesophageal fistula (AEF) is a relatively rare condition that often life-threatening. Secondary AEF complication of previous surgery, which can be more critical and challenging than primary AEF. The number secondary increasing due to increase in the thoracic endovascular aortic repair (TEVAR). Although TEVAR has become successful alternative surgical strategy for aneurysms, after might other because severe adhesion between esophagus residual wall. Methods This study...