EFREM D. FERREIRA

ORCID: 0000-0003-0901-3804
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Research Areas
  • Nutritional Studies and Diet
  • Diet and metabolism studies
  • Nutrition and Health in Aging
  • Obesity, Physical Activity, Diet
  • Liver Disease Diagnosis and Treatment
  • Health Systems, Economic Evaluations, Quality of Life
  • Colorectal Cancer Treatments and Studies
  • Birth, Development, and Health
  • Nutrition, Genetics, and Disease
  • Diet, Metabolism, and Disease
  • Folate and B Vitamins Research
  • Lipoproteins and Cardiovascular Health
  • Biochemical effects in animals
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Function and Risk Factors
  • Muscle metabolism and nutrition
  • Genetic Associations and Epidemiology
  • Diabetes Treatment and Management

Niigata University
2023-2025

Niigata University Medical and Dental Hospital
2022-2025

Niigata Institute of Technology
2024

To examine the association between a positive family history (parents, siblings, and grandparents) of type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia their prevalence incidence in same population. Data on 41,361 participants who underwent health examinations January 1, 1997, December 31, 2007, were analyzed, results logistic Cox regression analyses cohort examined. Cross-sectional showed that all three diseases increased with history, especially T2DM, an odds ratio (OR) 12.00...

10.1016/j.mayocp.2024.10.020 article EN cc-by-nc-nd Mayo Clinic Proceedings 2025-01-01

Abstract Background & Aims This study assessed the association of remission type 2 diabetes mellitus (DM) or metabolic dysfunction‐associated steatotic liver disease (MASLD)/related SLD (r‐SLD; MASLD with excessive alcohol intake) as defined by fatty index risk cardiovascular (CVD). Methods Health examination data at baseline and after years (2‐Years) were extracted from a nationwide claims database in Japan. Among participants aged 18–72 least 3 follow‐up, 9345 DM‐associated MASLD/r‐SLD...

10.1111/dom.16196 article EN cc-by-nc Diabetes Obesity and Metabolism 2025-01-15

Abstract Objective: To evaluate the association between dietary fiber intake and obesity in Japanese outpatients with type 2 diabetes, as well demographic factors influencing this association. Design: Cross-sectional study nationwide registry data on diabetes (2014-2019). Diet was self-reported via a Food Frequency Questionnaire. Obesity defined BMI ≥25 kg/m . Setting: Clinics throughout Japan. Participants: 1,565 (63.1% men; age range 30–89 years). Results: Multivariate analysis revealed...

10.1017/s136898002500014x article EN cc-by-nc-nd Public Health Nutrition 2025-02-04

Abstract Aims To determine the associations of body mass index (BMI) and waist circumference (WC) with severe diabetic complications in patients type 2 diabetes. Materials Methods In total, 114 254 participants diabetes (82% male; mean age, 52.52 ± 8.27 years; median follow‐up, 4.64 years) were enrolled from a nationwide Japanese medical claims database. Cox proportional models multivariate adjustment used to assess BMI WC treatment‐requiring eye disease (TRDED), initiation dialysis,...

10.1111/dom.16461 article EN Diabetes Obesity and Metabolism 2025-05-16

To analyze the association between dietary protein/energy ratio and percentages of animal plant protein obesity in Japanese patients with type 2 diabetes. This was a cross-sectional study. Obesity defined as BMI ≥25 kg/m2. Data were collected for all study participants stratified according to age sex. Diet assessed via food frequency questionnaire. 26 clinics participating Japan Diabetes Clinical Management Study Group (JDDM) from December 2014 2019. 1567 out diabetes (63.1% men; mean 62.3 ±...

10.1016/j.hnm.2024.200257 article EN cc-by-nc-nd Human Nutrition & Metabolism 2024-03-02

Background: Rice crackers are composed of carbohydrates refined from rice and enjoyed as a snack in Japan. Most crafted white rice, the potential postprandial blood glucose rise following their consumption may pose clinical concern. Brown contains more dietary fiber than has been reported to suppress elevations glucose. Dietary fiber-enhanced brown have significantly higher content regular can be expected reliably.Methods: We conducted crossover trial humans using investigate effect on...

10.31989/ffhd.v13i11.1231 article EN Functional Foods in Health and Disease 2023-11-14

We aimed to analyze the association between dietary iron intake and obesity assessed by BMI after adjustment for nutrient (macronutrients fiber) food groups. The study design was cross-sectional. Patients with type-2 diabetes (n = 1567; 63.1% males; mean age 62.3 ± 11.6 years) were included in study. To assess diet, consumption of typical groups determined a frequency questionnaire. Obesity defined as ≥ 25 kg/m2. performed binary regression analysis quartiles group. A direct linear found...

10.3390/nu14010211 article EN Nutrients 2022-01-04

That DM coexists with HT and/or DL is well known. To clarify this association, using a specialist clinic database from 1989 to 2022, we analyzed data on 2,630 Japanese at baseline aged ≥18 years and HbA1c ≥6.5% glucose-lowering drug prescription. Factors related remissions of in patients also remission during follow-up were studied. was defined as <6.5% for 3 months after cessation drug. Remission SBP <130 mmHg that HDLC non-HDLC ≥40 mg/dL <150 mg/dL, respectively...

10.2337/db24-66-pub article EN Diabetes 2024-06-14

Heritability and obesity are strongly associated with the prevalence of T2DM, HT, DL. We compared effects an FH DL combined on each in same population. Of 41931 participants who underwent health checkups, BMI those conditions were analyzed cross-sectionally. Prevalences 5%, 20%, 48%, respectively. Logistic regression analysis showed that ORs increased for all three as number positive cases was most pronounced T2DM. An additively diseases to 20.0-21.9 no (Fig. A). In addition, combination...

10.2337/db24-1666-p article EN Diabetes 2024-06-14

Although weight management plays a central role in diabetes treatment, the association between body and diabetic complications is not fully elucidated. Therefore, we investigated relationship BMI risk of patients with mellius (DM) using nationwide claims data. Analyzed were 91097 DM without prior treatment-requiring eye disease (TRDED), initiation dialysis (dialysis), coronary artery (CAD), cerebrovascular (CVD), heart failure (HF) or amputation (mean age 52 y, HbA1c 7.2%, median follow-up...

10.2337/db23-1357-p article EN Diabetes 2023-06-20

Insufficient sleep and late bedtime are associated with deteriorating glucose tolerance status, diabetes overweight. Although lifestyle in adulthood is influenced by childhood adolescent experiences, little known about the association between habits status children. Thus, we investigated overweight 1050 Japanese adolescents (497 boys) considering effects of diet, physical activity screen time. Overweight was defined International Obesity Task Force. Sleep duration wake/sleep time were based...

10.2337/db23-1718-p article EN Diabetes 2023-06-20

Although DR are important in managing diabetes, the traditional method, such as weighing foods and calculating nutrients, is burdensome to both patients medical care providers. photo with smartphones using AI identify dish calculate nutrients can be expected reduce this burden, accuracy not been clarified. Furthermore, it clear what extent improves when users dietitians adjust name of portion consumed compared only. In study, taken smartphone app were analyzed by only, then adjusted followed...

10.2337/db23-329-or article EN Diabetes 2023-06-20

Objective: To analyze the association between dietary protein/energy ratio and percentages of animal plant protein obesity in Japanese patients with type 2 diabetes.Design: This was a cross-sectional study. Obesity defined as BMI ≥25 kg/m2. Data were collected for all study participants stratified according to age sex. Diet assessed via food frequency questionnaire.Setting26 clinics participating Japan Diabetes Clinical Management Study Group (JDDM) from December 2014 2019.Participants1567...

10.2139/ssrn.4516780 preprint EN 2023-01-01
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