A5076596388- Pelvic and Acetabular Injuries
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Hip and Femur Fractures
- Pregnancy-related medical research
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Infectious Diseases and Tuberculosis
- Shoulder Injury and Treatment
- Sports injuries and prevention
- Abdominal Trauma and Injuries
- Shoulder and Clavicle Injuries
- Trauma Management and Diagnosis
- Medical Imaging and Analysis
- Bone health and osteoporosis research
- Orthopedic Surgery and Rehabilitation
- Diagnosis and treatment of tuberculosis
- Bone fractures and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Scoliosis diagnosis and treatment
- Medical Practices and Rehabilitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Alzheimer's disease research and treatments
- Cervical and Thoracic Myelopathy
- Reconstructive Surgery and Microvascular Techniques
University Hospital Leipzig
2017-2025
Leipzig University
2012-2023
German Society of Surgery
2022
Martin Luther University Halle-Wittenberg
2014-2021
Orthopädische Universitätsklinik
2020
Luther University
2015
Osteoporotic pelvic ring fractures are a rising problem for surgeons in industrialized countries. There is no evidence-based treatment strategy especially lateral compression (LC) involving the sacrum. The aim of this study was to evaluate and compare outcome survival rate nonoperative operative strategies fractures.In retrospective study, 128 patients (aged ≥65 years) with an Orthopedic Trauma Association (OTA) types B2.1 B3.3 fracture were included analyzed regarding demographic data...
The incidence of pelvic ring fractures in the elderly significantly increased. Because persistent pain and immobilization associated with this injury, surgical treatment is recommended. To minimise comorbidities risk, percutaneous techniques are becoming more relevant. In-screw cement augmentation sacroiliac screw fixation a promising procedure; however, clinical follow-up data remain scarce. This study investigated safety possible complications procedure along 1-year follow-up. Thirty-four...
Review article.A review of literature on the treatment pyogenic spondylodiscitis in geriatric patients was performed with aim to give an overview about these special and a recommendation necessary diagnostics as well conservative operative options.A systematic computerized search done by working group German Society for Orthopedics Trauma Surgery.Spondylodiscitis has increasing incidence age peak at 75 years or older. The 1-year mortality without appropriate is 15 20% extremely high....
Mortality of patients with a femoral neck fracture is high, especially within the first year after surgery, but also remains elevated thereafter. The aim this study was to identify factors potentially associated long-term mortality in homogeneously treated hemiarthroplasty for fracture.
Cancer resistance is a major cause for longevity of the naked mole-rat. Recent liver transcriptome analysis in this animal compared to wild-derived mice revealed higher expression alpha2-macroglobulin (A2M) and cell adhesion molecules, which contribute mole-rat's cancer resistance. Notably, A2M known dramatically decrease with age humans. We hypothesize that might facilitate tumour development. Here we found modulates adhesion, migration growth by inhibition promoting signalling pathways,...
Background: The fragility fractures of the pelvis (FFP) classification was established to address specific fracture morphology and dynamic instability in elderly. Although this system is frequently used, data on intra-rater inter-rater reliabilities are lacking. Methods: Six experienced 6 inexperienced surgeons 1 surgeon trained by originator FFP (“gold standard”) each used 3 times grade computed tomography (CT) scans 60 patients from hospitals. We assessed using Fleiss kappa statistics...
Despite an increasing number of fragility fractures the pelvis (FFP) over last 2 decades, controversy persists on their therapy with special regard to potential complications. Therefore, present study compared complication rates and in-hospital mortality non-operative therapy, percutaneous treatment open reduction internal fixation (ORIF) pelvic in elderly patients.All consecutive patients treated for FFP between January 2013 December 2017 aged 65 years or older were retrospectively...
Abstract Background Open reduction and plate fixation is a standard procedure for treating traumatic symphyseal disruptions, but has high incidence of implant failure. Several studies have attempted to identify predictors failure discussed its impact on functional outcome presenting conflicting results. Therefore, this study aimed investigate the pain outcome. Methods In single-center, retrospective, observational non-controlled cohort in level-1 trauma center from January 1, 2006, December...
Abstract Background Early operative treatment of acetabulum fractures in geriatric patients has been suggested to reduce pain and allow for earlier mobilization. The aim this study was determine mortality, complications functional outcome after non-operative treatment. Methods Patients aged ≥60 years with low-energy fragility fracture the from 2009 2016 a follow-up at least 24 months were identified. contacted by phone modified Merle d’Aubigné score obtained. If or their relatives not...
Fragility fractures of the pelvis are becoming increasingly important in an ageing society. However, they under-represented current research literature. In particular, unstable bilateral fragility sacrum (FFP IVb) benefit from surgical treatment, but individual fracture patterns need to be considered decision. This study describes sacral anatomy patients with FFP IVb pelvic fractures, particular emphasis on identification and evaluation possible trans-sacral screw corridors, transverse...
Although cement augmentation of pedicle screws increases stability, complications, such as pulmonary embolism, must be considered. One possible approach to minimize complication risk is not augmenting all screws. It remains unclear whether full necessary or if restricted sufficient regarding cement-associated implant failure, adjacent fractures. Is there a difference in failure rate, and revision rates non-cemented, fully augmented, cement-augmented long-segment posterior stabilization the...
Abstract With the new licensing regulations and National Competence-Based Learning Objectives Catalogue for Medicine (NKLM), learning objectives certificates of achievement are no longer assigned to specific subjects. In addition opportunity subject orthopaedics trauma surgery present itself more prominently at an earlier stage, there is also a need identify relevant subject-related in order integrate them into curricula prepare internal faculty discussions on teaching assignments. At...
Zusammenfassung Fragestellung Die aktuelle Richtlinie des Gemeinsamen Bundesausschusses fordert eine frühestmögliche operative Versorgung hüftgelenknaher Femurfrakturen innerhalb von 24 h nach Aufnahme zur Senkung der Komplikationsrate und Mortalität. Ziel Arbeit war es, Krankenhaussterblichkeit sowie -arten in Bezug auf die präoperative Wartezeit zu analysieren. Methodik Zwischen 2010 2020 wurden 575 Patienten mit Duokopfprothese Schenkelhalsfraktur retrospektiv hinsichtlich...
Zusammenfassung Die Epiphysiolyse des Dens axis ist eine seltene Verletzung im Kindesalter, welche jedoch bei typischen Pathomechanismen abgeklärt werde sollte. In unserem Fall konnte die einem 4‑jährigen Jungen nach Sturz auf den Nacken initialen Röntgen nicht diagnostiziert werden. Mittels Verlauf erfolgter MRT Diagnose gestellt und konservativ mit einer Zervikalstütze behandelt Im 10-Jahres-Follow-up zeigen sich milde Beeinträchtigungen, vor allem beim langen Verweilen in Flexionsstellung...
With an incidence of 0.3 per 100,000, spondylodiscitis is a rare condition in children. It typically bacterial origin and most commonly caused by Staphylococcus aureus. Bone involvement cat-scratch disease (CSD) due to Bartonella henselae exceedingly rare, occurring only 0.17–0.27% cases. We present the case 3-year-old boy with two-week history intermittent back pain recent onset fever. Initial laboratory findings were unremarkable, MRI revealed at L3/4 without abscess formation. Empirical...
Abstract Background Immunosuppressants such as mycophenolate mofetil (MMF) have the capacity to inhibit microglial and astrocytic activation reduce extent of cell death after neuronal injury. This study was designed determine effective neuroprotective time frame in which MMF elicits its beneficial effects, by analyzing glial proliferation, migration, apoptosis. Methods Using organotypic hippocampal slice cultures (OHSCs), temporal dynamics proliferation apoptosis N-methyl- D -aspartate...
The ligaments in coherence with the capsule of hip joint are known to contribute stability. Nevertheless, contribution mechanical properties and gender- or side-specific differences still not completely clear. To date, comparisons other tissues stabilizing pelvis joint, e.g. iliotibial tract, were performed.Hip obtained from 17 human cadavers (9 females, 7 males, 13 left 8 right sides, mean age 83.65 ± 10.54 years). 18 iliofemoral, 9 ischiofemoral pubofemoral prepared. Uniaxial stress-strain...