A5009449520- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- SARS-CoV-2 and COVID-19 Research
- Diet, Metabolism, and Disease
- Nail Diseases and Treatments
- COVID-19 Clinical Research Studies
- Bone Metabolism and Diseases
- Liver Disease Diagnosis and Treatment
- Orthodontics and Dentofacial Orthopedics
- Infectious Diseases and Mycology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Long-Term Effects of COVID-19
- COVID-19 epidemiological studies
- dental development and anomalies
- Cleft Lip and Palate Research
- Bacteriophages and microbial interactions
- S100 Proteins and Annexins
- Bone health and osteoporosis research
- Eicosanoids and Hypertension Pharmacology
- Sarcoidosis and Beryllium Toxicity Research
- Viral gastroenteritis research and epidemiology
- Cancer, Stress, Anesthesia, and Immune Response
- Pneumocystis jirovecii pneumonia detection and treatment
- Facial Rejuvenation and Surgery Techniques
- Liver Disease and Transplantation
Zhejiang University Medical College Affiliated Stomatological Hospital
2010-2025
Ningbo University Affiliated Hospital
2023-2025
Ningbo University
2019-2025
Stomatology Hospital
2025
Zhejiang University
2025
Ningbo First Hospital
2019-2023
Shanghai Pulmonary Hospital
2020
Tongji University
2020
Background No data is available about in-flight transmission of SARS-CoV-2. Here, we report an cluster COVID-19 and describe the clinical characteristics these patients.
Abstract Severe malocclusion can contribute to several serious dental and physical conditions, such as digestive difficulties, periodontal disease, severe tooth decay. Orthodontic treatment is mainly used treat malocclusion. Forces in orthodontic results bone resorption on the pressure side deposition tension side. Osteoblasts have been considered key component regeneration However, underlying mechanisms remain unclear. In this study, we focus how mechanical stretch regulates osteogenesis...
<title>Abstract</title> Background COPD is a respiratory disease with significant inflammatory characteristics. Low-dose aspirin widely used as an anti-inflammatory medicine. However, the impact of low-dose on unclear. This article aims to investigate association between and prevalence COPD. Methods A cohort study was conducted based United States population data from National Health Nutrition Examination Survey (NHANES) (2011–2012, 2013–2014, 2015–2016, 2017–2020, 2021–2023). We examined...
Background Lateral flow assay (LFA) has demonstrated high sensitivity and specificity for diagnosing cryptococcosis. However, its role in predicting therapeutic efficacy pulmonary cryptococcosis (PC) remains underexplored. Methods We conducted a retrospective analysis of HIV-negative patients with PC to describe the clinical profile identify potential predictors radiological prognosis. Results All 168 participants received antifungal therapy triazole agent. Of these, 84.5% experienced...
Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, an epidemic has spread rapidly worldwide. COVID-19 is caused by highly infectious severe acute respiratory syndrome coronavirus-2. A 42-year-old woman presented to hospital who was suffering from epigastric discomfort and dyspepsia for past 5 days. Before onset symptoms, she healthy, had no travel history Wuhan or contact with laboratory-confirmed cases. An examination showed chronic superficial gastritis erosion...
The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps increasing annually worldwide. Non-invasive assessment tools for evaluating the risk and severity are still limited. Insulin resistance (IR) abdominal obesity (ABO) closely related to NAFLD. A retrospective large-scale, population-based study was conducted based on data from 2017–2018 cycle National Health Nutrition Examination Survey (NHANES). Three ABO indices, namely lipid accumulation product (LAP), visceral index (VAI),...
Animal studies have reported on the benefits of ARB bone mass. However, underlying mechanism for angiotensin II (AngII)/AngII receptor blockade (ARB) in regulating mass remains elusive. Since high levels plasma and urine cAMP are observed osteoporotic hypertensive patients, we hypothesized that may be an important molecule downstream events activation AT receptors, members G-protein-coupled family, turnover. In this study, micro-CT X-ray analyses indicated AngII decreased via biasing...
Background: Hereditary gingival fibromatosis (HGF) is a rare benign disorder characterized by progressive overgrowth of gingiva. Although the clinical and histopathologic characteristics HGF are explicit, pathogenic mechanism remains unclear. The goal this article to describe three‐generation case discuss diagnosis, treatment, inheritance disease. known cellular molecular features also emphasized. Methods: Family medical histories patients were recorded, series preliminary examinations,...
Abstract Objectives No data were available about in-flight transmission of SARS-CoV-2. Here, we report an cluster COVID-19 and describe the clinical characteristics these patients. Methods After a flight, laboratory-confirmed was reported in 12 Ten patients admitted to designated hospital. Data collected from 25 th January 28 February 2020. Clinical information retrospectively collected. Results All are passengers without flight attendants. The median age 33 years, 70% females. None...
Cryptococcosis is the second most common invasive yeast infection in China. Pulmonary cryptococcosis (PC) difficult to diagnose due lack of specific clinical features and limitation diagnostic techniques. Although lateral flow assay was very useful diagnosing cryptococcal infection, quite a few patients with PC presented negative serum (sLFA).
Background: Talaromycosis is a serious fungal infection which rare in immunocompetent people. Since its clinical manifestations lack specificity, it easy to escape diagnosis or be misdiagnosed leading high mortality and poor prognosis. It necessary alert the disease when broad-spectrum antibiotics do not work well patients. Case Presentation: A 79-year-old man was admitted our Infectious Diseases Department for recurrent fever cough. Before admission he has been treated with...
External apical root resorption is among the most common risks of orthodontic treatment, and it cannot be completely avoided predicted. Risk factors causing can generally divided into patient- treatment-related factors. Root that occurs during treatment usually detected by radiographical examination. Mild or moderate absorption does no obvious harm, but close attention required. When severe occurs, recommended to suspend for 3 months cementum restored. To unify risk its clinical suggestions,...
<title>Abstract</title> Background The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps increasing annually all around the world. Non-invasive assessment tools for risk and severity are still limited. Insulin resistance (IR) abdominal obesity (ABO) closely related to NAFLD. Methods A retrospective large-scale, population-based study was conducted based on data from 2017–2018 cycle National Health Nutrition Examination Survey (NHANES). Three ABO indexes, namely lipid accumulation...
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic worldwide. Dietary acids are tightly associated with development of NAFLD while in-depth large-scale clinical researches few. Methods A retrospective case-control study was conducted based on data from 2017–2018 cycle National Health and Nutrition Examination Survey (NHANES). Weighted multivariable logistic regression, smooth curve fitting forest plot were used to describe relationships between...
<title>Abstract</title> Background Lateral flow assay (LFA) showed high sensitivity and specificity for diagnosing cryptococcosis. However, its predictive value therapeutic efficacy of pulmonary cryptococcosis (PC) was rarely reported. Methods We conducted a retrospective analysis on HIV-negative PC to present the clinical profile identify potential predictors radiological prognosis. Results All 168 participants received antifungal therapy with triazole agent. Of these, 84.5% experienced...
Cryptococcosis is a rare complication of sarcoidosis, especially when it grows in lungs. It may escape from being diagnosed because low prevalence and non-specific radiological presentation. Hereby, we reported an unusual case pulmonary cryptococcosis secondary to the long-term use glucocorticoids treat sarcoidosis which can be misdiagnosed as progression due similar After targeted therapy with fluconazole for 5 months, her chest computed tomography rescan revealed resolution lesions.
Abstract Cryptococcosis is an invasive fungal disease with increased morbidity in China. Cryptococci can infect immunocompromised hosts as well immunocompetent ones. In this study, we reviewed data of inpatients cryptococcosis at Ningbo First Hospital from May 2010 to 2020 and compared the clinical profiles pulmonary (PC) extrapulmonary (EPC). Of 71 patients enrolled, 70 were non-HIV dramatically prevalence especially PC. 77.46% cases PC confirmed by pathology. The rest EPC including...
Sarcoidosis is a multisystemic granulomatous disease of unknown etiology characterized by giant cell noncaseating granuloma, which can affect variety organs.Cryptococcus deep mycosis caused Cryptococcus neoformans infection; However, sarcoidosis patients with immunodeficiency and long-term use drugs such as glucocorticoids or immunosuppressants, lead to the coexistence these both diseases.Because combined Cryptococcosis rare, clinical understanding insufficient, pathogenesis unknown, it easy...
Voriconazole (C16H14N5OF3) is a novel triazole antifungal drug with broad spectrum, strong potency, good tolerance and high safety.It derivative of fluconazole, but it has broader antibacterial spectrum stronger bactericidal action than fluconazole.It can highly selectively inhibit the biosynthesis ergosterol in various fungal cell membranes.Voriconazole permeability to blood-brain barrier blood-eye barrier, thus reach multiple sites cryptococcal infection effective concentration.In...