Wanghui Ding

ORCID: 0000-0003-0645-4647
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Research Areas
  • Dental Radiography and Imaging
  • Dental Implant Techniques and Outcomes
  • Orthodontics and Dentofacial Orthopedics
  • dental development and anomalies
  • Obstructive Sleep Apnea Research
  • Osteoarthritis Treatment and Mechanisms
  • Neuroscience of respiration and sleep
  • Medical Imaging Techniques and Applications
  • Advanced X-ray and CT Imaging
  • Bone Tissue Engineering Materials
  • Cleft Lip and Palate Research
  • NF-κB Signaling Pathways
  • Cancer, Hypoxia, and Metabolism
  • 3D Printing in Biomedical Research
  • Cancer-related molecular mechanisms research
  • Temporomandibular Joint Disorders
  • Anatomy and Medical Technology
  • Bone Metabolism and Diseases
  • Hydrogen's biological and therapeutic effects
  • Dental Research and COVID-19
  • Natural product bioactivities and synthesis
  • Cellular Mechanics and Interactions
  • Fibroblast Growth Factor Research
  • Sinusitis and nasal conditions
  • Bone and Dental Protein Studies

Stomatology Hospital
2014-2025

Zhejiang University
2013-2025

Zhejiang University Medical College Affiliated Stomatological Hospital
2018

Tongji University
2009

An ideal biomimetic periosteum is expected to wrap various bone surfaces orchestrate an optimal microenvironment for regeneration, including facilitating local vascularization, recruiting osteoblasts, and mineralizing the extracellular matrix (ECM). To mimic role of natural in promoting repair, a 4D printing technique inlay aligned cell sheets on shape-shifting hydrogel used, containing biophysical signals spatially adjustable physical properties, first time. The outer layer endows with...

10.1002/adhm.202202868 article EN Advanced Healthcare Materials 2023-05-12

Summary The purpose of this study was to compare the differences in cephalometric parameters after active orthodontic treatment applying mini‐screw implants (G1) or transpalatal arches (G2) as anchorage adult patients with bialveolar dental protrusion needing extraction four premolars. A total 34 Chinese (18–33 years) were randomly assigned G1 and G2. Sliding mechanics en‐masse retraction anterior teeth applied close spaces. changes skeletal, soft tissues analyzed both groups on lateral...

10.1111/j.1365-2842.2009.01976.x article EN Journal of Oral Rehabilitation 2009-07-10

Objective Molar intrusion by mini-screw implantation can cause different degrees of root resorption. However, most methods (2-D and 3-D) used for evaluating resorption have focused on the length without considering 3-D The purpose this study was to volumetrically evaluate using cone beam computed tomography(CBCT) after implant intrusion. Materials Methods 1. volumes 32 teeth were measured CBCT laser scanning verify accuracy CBCT. 2. Twelve overerupted molars from adult patients investigated...

10.1371/journal.pone.0060962 article EN cc-by PLoS ONE 2013-04-09

Temporomandibular joint osteoarthrosis (TMJOA) is characterised by chronic inflammatory changes, with subsequent gradual loss of cartilage. NF-κB a crucial transcription factor in the course and immune responses, which are involved OA pathology activated proinflammatory cytokines. Genistein known to have anti-inflammation modulation metabolic pathways through repression signaling pathway disease. But so far, studies on effects genistein TMJOA very limited. So, purpose this study investigate...

10.1155/2019/2629791 article EN BioMed Research International 2019-12-30

Abstract Severe malocclusion can contribute to several serious dental and physical conditions, such as digestive difficulties, periodontal disease, severe tooth decay. Orthodontic treatment is mainly used treat malocclusion. Forces in orthodontic results bone resorption on the pressure side deposition tension side. Osteoblasts have been considered key component regeneration However, underlying mechanisms remain unclear. In this study, we focus how mechanical stretch regulates osteogenesis...

10.1038/s41419-018-0279-5 article EN cc-by Cell Death and Disease 2018-02-12

Abstract Background Orthodontically induced root resorption (OIRR) is a common side effect of orthodontic treatment. This study compares the degree OIRR between root-filled teeth (RFT) and vital pulp (VPT), analyzes relevant variables. Methods We conducted retrospective on 69 patients who had undergone Using Cone-beam computed tomography (CBCT), we measured changes length before after treatment through unique method involving three-dimensional (3D) image registration superimposition. Factors...

10.1186/s40510-025-00553-7 article EN cc-by Progress in Orthodontics 2025-02-27

Obstructive sleep apnea and hypopnea syndrome (OSAHS) is a clinical characterized by recurrent episodes of obstruction the upper airway during that leads to hypoxic condition. Genioglossus, an important pharyngeal muscle, plays role in maintaining open for effective breathing. Our previous study found genistein (a kind phytoestrogen) protects genioglossus muscle from hypoxia-induced oxidative injury. However, underlying mechanism still unknown. In present study, we examined effects hypoxia...

10.1038/s41598-017-03484-4 article EN cc-by Scientific Reports 2017-07-05

Summary The purpose of this study is to examine the relationship between molar intrusion efficiency and bone density in patients with different vertical facial morphology. Thirty‐six female patients, overerupted upper first molars, were divided into two groups according mandiblular plane angle ( FH ‐ MP ): hyperdivergent, >30° (G1), hypodivergent, <22° (G2). Mini‐screw implants elastic chains used intrude molars. Spiral CT was measure degree density, calculated as amount/duration (mm...

10.1111/joor.12261 article EN Journal of Oral Rehabilitation 2014-12-16

Abstract Cone-beam computed tomography (CBCT) is one of the most widely used digital models in dental practices. A critical step virtual treatment planning to accurately delineate all tooth-bone structures from CBCT with high fidelity. Previous studies have established several methods for segmentation using deep learning. However, inherent resolution discrepancy and loss occlusal information largely limited its clinical applicability. Here, we present a Deep Dental Multimodal Analysis (DDMA)...

10.21203/rs.3.rs-1472915/v1 preprint EN cc-by Research Square (Research Square) 2022-03-21

Abstract Objectives This study aimed to compare and evaluate different transverse width indices for diagnosing maxillary deficiency (MTD), a common malocclusion characterized by uncoordinated dental arches, crossbites, tooth crowding. Materials methods Sixty patients aged 7–12 years were included in the study, with 20 diagnosed MTD 40 normal controls. Transverse indices, including at buccal alveolar crest lingual midroot level, as well jugal process width, measured. Differences between these...

10.1186/s12903-024-04580-4 article EN cc-by BMC Oral Health 2024-07-17

To investigate the effects of genistein on genioglossus muscle function and nuclear factor erythroid 2 related 2(Nrf-2)/antioxidant responsive element(ARE) signaling pathway in rats under chronic intermittent hypoxia(CIH) condition order to find medication treatment obstructive sleep apnea/hyponea syndrome.Thirty female Sprague-Dawley(SD) (8 weeks old) were randomly(random number table) divided into three groups 1 week after ovariectomy: control group(NC group), CIH group, CIH+genistein...

10.3760/cma.j.issn.1002-0098.2016.01.011 article EN PubMed 2016-01-01

Obstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized by intermittent and recurrent upper airway collapse during that leads to chronic hypoxia (CIH). The genioglossus (GG) the largest dilator muscle, which controls plays an important role in OSA pathology. Elucidating its genetic alterations may help identify potential targets for OSA. However, aspects of GG CIH mice remain unclear. Here, we have conducted RNA sequencing (RNA-Seq) analysis assess differentially...

10.1016/j.resp.2022.103980 article EN cc-by-nc-nd Respiratory Physiology & Neurobiology 2022-10-20

In computer-assisted orthodontics, three-dimensional tooth models are required for many medical treatments. Tooth segmentation from cone-beam computed tomography (CBCT) images is a crucial step in constructing the models. However, CBCT image quality problems such as metal artifacts and blurring caused by shooting equipment patients' dental conditions make difficult. this paper, we propose ToothSegNet, new framework which acquaints model with generated degraded during training. ToothSegNet...

10.1109/isbi53787.2023.10230557 article EN 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI) 2023-04-18

To establish a novel deep learning networks (MSF-MPTnet) based on panoramic radiographs (PRs) for automatic assessment of relationship between maxillary sinus floor (MSF) and posterior teeth (MPT), to compare accuracy MSF-MPTnet, dentists radiologists identifying contact relationship.

10.1016/j.heliyon.2024.e31052 article EN cc-by-nc-nd Heliyon 2024-05-01

In computer-assisted orthodontics, three-dimensional tooth models are required for many medical treatments. Tooth segmentation from cone-beam computed tomography (CBCT) images is a crucial step in constructing the models. However, CBCT image quality problems such as metal artifacts and blurring caused by shooting equipment patients' dental conditions make difficult. this paper, we propose ToothSegNet, new framework which acquaints model with generated degraded during training. ToothSegNet...

10.48550/arxiv.2307.01979 preprint EN other-oa arXiv (Cornell University) 2023-01-01

4D Printing In article 2202868 by Binbin Ying, Wanghui Ding, Mengfei Yu, and co-workers, the process of bone defect repair mediated biomimetic periosteum is vividly conveyed through famous Chinese folk story “The Coilang Weaver Meet on Bridge”. The constructed ultraviolet light-based micropattern printing contains biophysical signals spatially adjustable properties, which expected to orchestrate an optimal microenvironment for regeneration. (the bridge in cartoon) provides a channel host...

10.1002/adhm.202370130 article EN Advanced Healthcare Materials 2023-09-01

Objectives: To establish a novel deep learning networks (MSF-MPTnet) based on panoramic radiographs (PRs) for automatic assessment of relationship between maxillary sinus floor (MSF) and posterior teeth (MPT), to compare accuracy MSF-MPTnet, dentists radiologists identifying contact relationship.Study Design: A total 1035 PRs CBCT were collected from January 2018 April 2022. The relationships classified into class I II by CBCT. Class represents non-contact group, group. 370 randomly selected...

10.2139/ssrn.4568786 preprint EN 2023-01-01
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