X.Y. Chen

ORCID: 0000-0002-4966-1040
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About
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Research Areas
  • Neurosurgical Procedures and Complications
  • Intracerebral and Subarachnoid Hemorrhage Research
  • dental development and anomalies
  • Acute Ischemic Stroke Management
  • Anesthesia and Neurotoxicity Research
  • Vitamin D Research Studies
  • Obstructive Sleep Apnea Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac, Anesthesia and Surgical Outcomes
  • Dental Implant Techniques and Outcomes
  • Dental Radiography and Imaging
  • Tuberculosis Research and Epidemiology
  • Cleft Lip and Palate Research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Cytomegalovirus and herpesvirus research
  • Bone health and treatments
  • Temporomandibular Joint Disorders
  • Orthodontics and Dentofacial Orthopedics
  • Chronic Kidney Disease and Diabetes
  • Parathyroid Disorders and Treatments
  • Intensive Care Unit Cognitive Disorders
  • Vestibular and auditory disorders

First Affiliated Hospital of Fujian Medical University
2025

Fujian Medical University
2025

Second Affiliated Hospital of Zhejiang University
2025

Zhejiang University
2014-2024

Stomatology Hospital
2024

First Affiliated Hospital of Xi'an Jiaotong University
2008

<h3>Objective:</h3> To clarify associations between intracerebral hemorrhage (ICH) location and clinical outcomes among participants of the main phase Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2). <h3>Methods:</h3> Associations ICH sites poor (death [6] or major disability [3–5] modified Rankin Scale) European Quality Life Scale (EQ-5D) utility scores at 90 days were assessed logistic regression models. <h3>Results:</h3> Of 2,066 patients included...

10.1212/wnl.0000000000003771 article EN cc-by Neurology 2017-02-25

<h3>Objectives:</h3> To investigate the effects of intensive blood pressure (BP) lowering according to baseline BP levels and optimal achieved in patients with acute intracerebral hemorrhage (ICH). <h3>Methods:</h3> INTERACT2 was an open, blinded endpoint, randomized controlled trial 2,839 ICH within 6 hours onset elevated systolic (SBP) (150–220 mm Hg) who were allocated receive (target SBP &lt;140 Hg 1 hour, lower limit 130 for treatment cessation) or guideline-recommended &lt;180...

10.1212/wnl.0000000000001205 article EN Neurology 2015-01-01

BACKGROUND: The frequency and prognostic significance of subacute neurological improvement (SNI) on 90-day outcomes after acute intracerebral hemorrhage are unknown. METHODS: Secondary analyses participant data from the INTERACT2 trial (second Intensive Blood Pressure Reduction in Acute Intracerebral Hemorrhage Trial). SNI included any, moderate, significant, substantial defined as ≥1, ≥2, ≥3, ≥4 points decrease, respectively, National Institutes Health Stroke Scale 24 hours to 7 days...

10.1161/strokeaha.124.048847 article EN Stroke 2025-02-03

The kidney-brain interaction has been a topic of growing interest. Past studies the effect kidney function on intracerebral hemorrhage (ICH) outcomes have yielded inconsistent findings. Although second, main phase Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2) suggests effectiveness early intensive blood pressure (BP) lowering improving functional recovery after ICH, balance potential benefits and harms this treatment those with decreased remains...

10.1053/j.ajkd.2016.01.020 article EN cc-by-nc-nd American Journal of Kidney Diseases 2016-03-03

Objective This study compared the efficacy of microwave ablation (MWA) and parathyroidectomy (PTX) in treatment secondary hyperparathyroidism (SHPT) evaluated improvement bone metabolic markers (BMMs) mineral density (BMD). Materials methods Eligible patients with SHPT treated between January 2019 August 2022 were enrolled divided into two groups: MWA PTX. Outcome measures included success rate, percentage whose intact parathyroid hormone (iPTH) concentration was within target range, serum...

10.3389/fendo.2025.1424248 article EN cc-by Frontiers in Endocrinology 2025-03-10

Intraoperative hypercapnia reduces the time to emergence from volatile anesthetics, but few clinical studies have explored effect of on intravenous (IV) anesthesia. We investigated inducing mild during recovery period after total IV anesthesia (TIVA). Adult patients undergoing transurethral lithotripsy under TIVA were randomly allocated normocapnia group (end-tidal carbon dioxide [ETCO2] 35-40 mmHg) or (ETCO2 50-55 period. The primary outcome was extubation time. spontaneous breathing-onset...

10.4097/kja.24363 article EN cc-by-nc Korean journal of anesthesiology 2025-04-17

Summary The purpose of this study is to examine the relationship between molar intrusion efficiency and bone density in patients with different vertical facial morphology. Thirty‐six female patients, overerupted upper first molars, were divided into two groups according mandiblular plane angle ( FH ‐ MP ): hyperdivergent, &gt;30° (G1), hypodivergent, &lt;22° (G2). Mini‐screw implants elastic chains used intrude molars. Spiral CT was measure degree density, calculated as amount/duration (mm...

10.1111/joor.12261 article EN Journal of Oral Rehabilitation 2014-12-16

: Alveolar bone loss is a common adverse effect of intrusion treatment. Mandibular incisors are prone to dehiscence and fenestrations as they suffer from thinner alveolar thickness.

10.4041/kjod23.173 article EN cc-by-nc The Korean Journal of Orthodontics 2024-02-28

To evaluate the airway space in bilateral idiopathic condylar resorption (ICR) patients and analyse correlation between morphological characteristics of condyles parameters. In all, 35 female with ICR (mean age: 21.6 years) age-matched controls 21.3 were included. Airway parameters measured using CBCT. Independent T-tests used to differences group control group, then was detected Pearson analysis. p < .05 considered statistically significant. Patients showed a significant decrease volume,...

10.1111/ocr.12855 article EN Orthodontics and Craniofacial Research 2024-09-15
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