A5024358828- Salmonella and Campylobacter epidemiology
- Bacteriophages and microbial interactions
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Antibiotic Resistance in Bacteria
- CRISPR and Genetic Engineering
- Escherichia coli research studies
- Bacterial biofilms and quorum sensing
- Cancer Research and Treatments
- Antimicrobial Resistance in Staphylococcus
- Aquaculture disease management and microbiota
- Genomics and Phylogenetic Studies
- Listeria monocytogenes in Food Safety
- Bacterial Identification and Susceptibility Testing
- Viral Infections and Immunology Research
- Identification and Quantification in Food
- Animal Virus Infections Studies
- Trace Elements in Health
- Microbial Metabolism and Applications
- RNA and protein synthesis mechanisms
- NF-κB Signaling Pathways
- Alkaloids: synthesis and pharmacology
- Bacterial Infections and Vaccines
- Zoonotic diseases and public health
- Microbial Natural Products and Biosynthesis
Yangzhou University
2016-2025
University of Copenhagen
2016-2021
Ministry of Agriculture and Rural Affairs
2019
Ministry of Education of the People's Republic of China
2017
Zhangzhou Normal University
2014
Abstract Background Infection with Salmonella enterica usually results in diarrhea, fever, and abdominal cramps, but some people become asymptomatic or chronic carrier as a source of infection for others. This study aimed to analyze the difference serotype, antimicrobial resistance, genetic profiles between strains isolated from patients those Nantong city, China. Methods A total 88 were collected 2017 2018. Serotyping, susceptibility testing, PFGE analysis performed characteristics these...
Salmonella enterica subspecies serovar Gallinarum biovar Pullorum (S Pullorum) is the etiological agent of pullorum disease, causing white diarrhea with high mortality in chickens. There are many unsolved issues surrounding epidemiology S Pullorum, including its origin and transmission history as well discordance between phenotypic heterogeneity genetic monomorphism. In this paper, we report results whole-genome sequencing a panel 97 strains isolated 1962 2014 from four countries across...
ABSTRACT Salmonella enterica serovar Kentucky ( S. Kentucky) has been regarded as a common serotype causing human nontyphoidal salmonellosis, frequently associated with the consumption of contaminated poultry products. Recently, multidrug-resistant (MDR) S . ST198 strong resistance to cefotaxime, ciprofloxacin, and tigecycline emerged detected in both humans Europe Asia. In this study, whole-genome sequencing (WGS) analysis divided 327 isolates into two clades, which ST198.2 is more...
Tigecycline serves as a last-resort antimicrobial agent against severe infections caused by multidrug-resistant bacteria. Tet(X) and its numerous variants encoding flavin-dependent monooxygenase can confer resistance to tigecycline, with tet (X4) being the most prevalent variant. This study aims investigate prevalence characterize tigecycline gene (X) in E. coli isolates from various origins Yangzhou, China, provide insights into dissemination this region. In 2022, we tested presence of 618...
Salmonella spp. are important foodborne pathogens, and multidrug-resistant (MDR) strains have become a serious threat to clinical therapy. MDR S .
Salmonella enterica subsp. serovar 4,[5],12:i:- (Salmonella 4,[5],12:i:-), derived from S. Typhimurium, has become the dominant serotype causing human salmonellosis. In this study, we define genetic mechanism of generation Typhimurium through complicated transpositions and demonstrate that displays more efficient colonization survival abilities in mice than its parent strain. We identified intermediate strains carrying both resistance regions (RRs) fljAB operon for 4,[5],12:i:-. The...
Salmonellosis, caused by non-typhoidal Salmonella , is a common foodborne gastrointestinal infection. Third-generation cephalosporins are recommended as the first-line treatment for infections. Our study aimed to investigate molecular epidemiology, antimicrobial resistance, and transmission of extended-spectrum β-lactamases (ESBL) genes in 96 clinical isolates collected between 2020 2022 at tertiary hospital Shenzhen, China. We performed susceptibility testing whole-genome sequencing...
Salmonella enterica subsp. serovar Gallinarum biovar Pullorum (Salmonella Pullorum) is highly adapted to chickens causing an acute systemic disease that results in high mortality. Vaccination represents one approach for promoting animal health, food safety and reducing environmental persistence control. An important consideration vaccination poultry should not interfere with the salmonellosis monitoring program. This basis of DIVA (Differentiation Infected Vaccinated Animals) In order...
Salmonella enterica serovar Gallinarum biovar Pullorum (S. Pullorum) is the pathogen of pullorum disease, which leads to severe economic losses in many developing countries. Traditional methods identify S. have relied on biochemical reactions and serotyping, are time-consuming with accurate identification if properly carried out. In this study, we developed a rapid polymerase chain reaction (PCR) method targeting specific gene ipaJ detect Pullorum. Among 650 strains isolated from 1962 2016...
Salmonella is a worldwide foodborne pathogen causing human disease. Food handlers, who are potential carriers of Salmonella, may transmit the to consumers through food. To determine prevalence enterica serovars among food handlers working in catering industry Nantong, China, total 214,542 handlers' fecal samples were tested for Nantong CDC (Centers Disease Control) from 2012 2017. Among those tested, 193 (0.09%) identified be positive and highest detection rate was 0.16% during period July...
Salmonella enterica serovar Pullorum (S. Pullorum) is a highly adapted pathogen that causes pullorum disease (PD), an important systemic of poultry severe economic losses in developing countries. In the interests safe and immunogenic oral vaccine, efficacy pathogenicity island 2 (SPI2)-deleted mutant S. (S06004ΔSPI2) was evaluated chickens. S06004ΔSPI2 severely less virulent than parental wild-type strain S06004 as determined by 50% lethal dose (LD50) for 3-day-old chickens when injected...
In this study, a carbapenem-resistant Salmonella enterica serovar Typhimurium strain W131 (sequence type 34) was isolated from retail pork in Jiangsu province, China. An IncX3 plasmid carrying blaNDM-5 element identified by whole-genome sequencing analysis. The conjugation experiment demonstrated that the can be transferred to Escherichia coli recipient J53 and conferred carbapenem resistance strain. This study first reported with pork, which revealed meat as potential transmission factor of...