A5050949626- Lipoproteins and Cardiovascular Health
- Cardiac Valve Diseases and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Pharmaceutical Economics and Policy
- Biomedical and Engineering Education
- Coronary Interventions and Diagnostics
- Aortic Thrombus and Embolism
- Fractional Differential Equations Solutions
- Cardiovascular Health and Risk Factors
- Infections and bacterial resistance
- Acute Myocardial Infarction Research
- Medical Imaging and Pathology Studies
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Child Nutrition and Water Access
- S100 Proteins and Annexins
- Blood disorders and treatments
- IgG4-Related and Inflammatory Diseases
University of Toronto
2014-2021
Health Sciences Centre
2014-2021
Sunnybrook Health Science Centre
2014-2021
McGill University
2016-2020
Gentofte Hospital
2016
Copenhagen University Hospital
2016
Frederiksberg Hospital
2016
University of Copenhagen
2016
Allegheny General Hospital
2016
University of Arizona
2016
GlycA, an emerging inflammatory biomarker, predicted cardiovascular events in population-based studies. Psoriasis, disease associated with increased risk, provides a model to study biomarkers (CVD). Whether GlycA associates psoriasis and how it predicts subclinical CVD beyond high-sensitivity C-reactive protein is unknown.To investigate the relationships between CVD.Patients controls (n=412) participated 2-stage study. We measured by nuclear magnetic resonance spectroscopy. National...
Background Current recommendations for lipoprotein(a) (Lp[a]) focus on the control of other risk factors, including lowering low‐density lipoprotein cholesterol ( LDL ‐C), with little evidence to support this approach. Identifying interactions between Lp(a) and factors could identify individuals at increased Lp(a)‐mediated disease. Methods Results We used a case‐only study design included 939 participants (median age=49 years, interquartile range 46–53, women=33.1%) from GENdE r Sex...
High lipoprotein(a) (Lp[a]) is the most common genetic dyslipidemia and a causal factor for myocardial infarction (MI) aortic stenosis (AS). We sought to estimate population impact of Lp(a) lowering that could be achieved in primary prevention using therapies development.We used published data from 2 prospective cohorts. was defined as ≥50 mg/dL (≈20th percentile). Relative risk, attributable risk percentage, percentage were calculated measures impact. For MI, event rate 4.0% versus 2.8%...
Background Elevated lipoprotein(a) is a well‐established risk factor for atherosclerotic vascular disease but not measured in routine clinical care. Screening of high individuals with moderate elevations low‐density lipoprotein cholesterol (LDL‐C) may identify at cardiovascular disease. Methods and Results We examined 2606 Framingham Offspring participants (median age, 54 years; 45% men) prospectively median follow‐up 15 years (n=392 incident events). Individuals higher (≥100 nmol/L) versus...
Advancement of medicine and that biochemistry are inseparable, much modern would not be practiced in the ways, as they known today, without our understanding how genetic, pathogenic environmental factors affect human body at biochemical level. Thus, importance teaching medical students is self-evident. Ironically, many practicing physicians consider learning an unnecessary burden has very little relevance to their daily practice [1–3]. Also, students, especially those interested fields such...
Natural killer (NK) cells can lyse certain tumor as well virally infected without prior sensitization.Animal studies have shown that general anesthesia (GA) alone or GA followed by surgery decreases both basal NK cytotoxicity and enhancement of activity interferon (IFN). The purpose this study was to determine whether similar inhibition occurs in humans. Venous blood drawn 1 h before 20-24 after under isoflurane/N2 O anesthesia. Peripheral mononuclear (PBMC) were assayed for...
Subarachnoid inflammation following spinal cord injury (SCI) can lead to the formation of localized subarachnoid scarring and development post-traumatic syringomyelia (PTS). While PTS is a devastating complication SCI, its relative rarity (occurring symptomatically in about 5% clinical cases), lack fundamental physiological insights, have led us examine an animal model traumatic SCI with induced arachnoiditis. We hypothesized that arachnoiditis associated would potentiate early parenchymal...
Natural killer (NK) cells can lyse certain tumor as well virally infected without prior sensitization.Animal studies have shown that general anesthesia (GA) alone or GA followed by surgery decreases both basal NK cytotoxicity and enhancement of activity interferon (IFN). The purpose this study was to determine whether similar inhibition occurs in humans. Venous blood drawn 1 h before 20-24 after under isoflurane/N2 O anesthesia. Peripheral mononuclear (PBMC) were assayed for...
Peritoneal dialysis-related peritonitis remains a major complication of peritoneal dialysis in patients with end-stage renal disease. Chryseobacterium indologenes is rare organism that has been reported to cause infections mostly hospitalised severe underlying diseases. We report the first case C patient on outside Asia. Our disease grew from fluid when he presented abdominal pain and cloudy effluent. The responded well intraperitoneal antibiotic therapy. Tenckhoff catheter did not require...
A 67-year-old man who had previously heart transplantation and chronic kidney disease underwent coronary angiography. He received pretreatment owing to a reported history of iodine allergy but neck swelling several hours later.
In the present study, a collocation procedure based upon two different polynomials (Bessel and Legendre) is presented to solve modified nonlinear epidemiological model of computer viruses, which three-dimensional system ordinary differential equations (ODEs) with quadratic nonlinearities. Representing unknown solutions their derivatives in matrix forms along points, approximation algorithm transforms given into equation. addition direct Bessel or Legendre-collocation method, combination idea...