A5067636692- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Analytical chemistry methods development
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Mycotoxins in Agriculture and Food
- Metal-Organic Frameworks: Synthesis and Applications
- Carbon Dioxide Capture Technologies
- Membrane Separation and Gas Transport
- Covalent Organic Framework Applications
- Advanced Photocatalysis Techniques
- Legionella and Acanthamoeba research
- Botanical Research and Applications
- Essential Oils and Antimicrobial Activity
- Phase Equilibria and Thermodynamics
- Analytical Chemistry and Sensors
- Natural product bioactivities and synthesis
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Molecular Junctions and Nanostructures
- Pharmacological Effects of Natural Compounds
- COVID-19 Clinical Research Studies
- Paraquat toxicity studies and treatments
- Lymphadenopathy Diagnosis and Analysis
- Plant chemical constituents analysis
Majmaah University
2019-2024
Alfaisal University
2023-2024
King Saud University
2023
Institut des Sciences Analytiques
2012-2021
Université Claude Bernard Lyon 1
2012-2021
Centre National de la Recherche Scientifique
2012-2021
University of Monastir
2012-2021
Laboratoire des Matériaux Avancés
2015
Interface (United States)
2015
Cancer is a leading cause of death worldwide and its incidence unfortunately anticipated to rise in the next years. On other hand, vascular endothelial growth factor receptor 2 (VEGFR-2) highly expressed tumor-associated cells, where it affects tumor-promoting angiogenesis. Therefore, VEGFR-2 considered one most promising therapeutic targets for cancer treatment. Furthermore, some FDA-approved benzimidazole anthelmintics have already shown potential anticancer activities. repurposing them...
The detection of pathogenic bacteria remains a challenge for the struggle against biological weapons, nosocomial diseases, and food safety. In this research, our aim was to develop an easy-to-use electrochemical immunosensor Staphylococcus aureus ATCC25923. biosensor elaborated by immobilization anti-S. antibodies using self-assembled monolayer (SAMs) 3-Mercaptopropionic acid (MPA). These molecular assemblies were spontaneously formed immersion substrate in organic solvent containing SAMs...
A sensitive electrochemical molecularly-imprinted sensor was developed for the detection of aflatoxin B1 (AFB1), by electropolymerization p-aminothiophenol-functionalized gold nanoparticles in presence AFB1 as a template molecule. The extraction leads to formation cavities that are able specifically recognize and bind through π-π interactions between molecules aniline moities. performance investigated linear sweep voltammetry using hexacyanoferrate/hexacyanoferrite solution redox probe,...
Hydroxyethylamine and hydroxyethylene moieties of β-blockers exert potential SARS-CoV-2 inhibitory effects: rational-based design in silico , vitro SAR Studies.
In late December 2019, a novel coronavirus, namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), escaped the animal–human interface and emerged as an ongoing global pandemic with flu-like illness, commonly known disease 2019 (COVID-19). this study, molecular docking study was carried out for seventeen (17) structural analogues prepared from natural maslinic oleanolic acids, screened against SARS-CoV-2 main protease. Furthermore, we experimentally validated virtual data by...
The key solution to combat trace metal pollution and keep the environment, ecosystem, animals, humans safe is earlier rapid detection. For all these reasons, we propose in this work design of a simple electrochemical sensor functionalized with green nanoparticles for detection fourth most dangerous heavy ions namely copper, zinc, lead, mercury. are fabricated by one-step, consisting reducing platinum natural gum Arabic polymer. To guarantee success nanoparticles' design, have been...
Diabetes mellitus is a major health problem globally. The management of carbohydrate digestion provides an alternative treatment. Flavonoids constitute the largest group polyphenolic compounds, produced by plants widely consumed as food and/or used for therapeutic purposes. As such, isoxazoles have attracted attention medicinal chemists dint their considerable bioactivity. Thus, main goal this work was to discover new hybrid molecules with properties both flavonoids and in order control...
To protect consumers from risks related to overexposure sulfadiazine, total residues of this antibacterial agent in animal-origin foodstuffs not exceed international regulations. end, a new electrochemical sensor based on molecularly imprinted polymer nanocomposite using overoxidized polypyrrole and copper nanoparticles for the detection sulfadiazine is elaborated. After optimization preparation sensors, their differential pulse voltammetric signal exhibits an excellent stability...
Abstract In recent years, the presence of heavy metal ions in food chains and water poses serious environmental human health problems. Therefore, there has been a pressing need for fast simple, sensitive, accurate methods their detection. this study novel electrochemical sensor based on alginate sodium biopolymer decorating single‐walled carbon nanotubes was elaborated detection trace level ions. Different brown algae were used to extract alginate, with Cystoseira being most common. Due its...
Abstract Metallic green nanoparticles based on gum arabic (GA) biopolymer have attracted a great deal of attention in numerous applications, especially electrochemical sensor design for environmental monitoring. One the most harmful contaminants that threaten safety is glyphosate molecule. For this purpose, we report, herein, synthesis novel platinum decorated by GA to develop new, rapid, and efficient trace detection. To control morphology, dispersion, size, structure Platinum...
Abstract This study introduces an innovative electrochemical aptasensor designed for the highly sensitive and rapid detection of Legionella pneumophila serogroup 1 ( L. SG1 ), a particularly virulent strain associated with Legionellosis. Employing rigorous selection process utilizing cell-based systematic evolution ligands by exponential enrichment (cell-SELEX), we identified new high-affinity aptamers specifically tailored . The encompassed ten rounds cell-SELEX cycles live , including...
An impedimetric immunosensor for detection of ochratoxin A is fabricated on a planar BDD electrochemical microcell through electroaddressing antibodies.
In this study, we investigated a novel aflatoxin biosensor based on acetylcholinesterase (AChE) inhibition by B1 (AFB1) and developed electrochemical biosensors sodium alginate biopolymer as new matrix for immobilization. Electrochemical impedance spectroscopy was performed convenient transduction method to evaluate the AChE activity through oxidation of metabolic product, thiocholine. Satisfactory analytical performances in terms high sensitivity, good repeatability, long-term storage...