A5061239510- Venous Thromboembolism Diagnosis and Management
- Angiogenesis and VEGF in Cancer
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Aortic aneurysm repair treatments
- Central Venous Catheters and Hemodialysis
- Diagnosis and Treatment of Venous Diseases
- Poisoning and overdose treatments
- Liver Disease Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Healthcare Policy and Management
- Vascular anomalies and interventions
- Primary Care and Health Outcomes
- Peripheral Nerve Disorders
- Global Health Workforce Issues
- Cerebral Venous Sinus Thrombosis
- Electrospun Nanofibers in Biomedical Applications
- Sulfur Compounds in Biology
- Cervical and Thoracic Myelopathy
- Medical Imaging Techniques and Applications
- Mesenchymal stem cell research
- Emergency and Acute Care Studies
- Coronary Artery Anomalies
- Hippo pathway signaling and YAP/TAZ
- Pharmacy and Medical Practices
The Seventh Affiliated Hospital of Sun Yat-sen University
2025
Sun Yat-sen University
2025
Nanchang University
2013-2025
Second Affiliated Hospital of Nanchang University
2014-2025
Nanjing Medical University
2024-2025
Second Affiliated Hospital of Nanjing Medical University
2025
Peking Union Medical College Hospital
2019
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
China Postdoctoral Science Foundation
2019
Boston University
2013-2017
Aortic aneurysm is a life-threatening disease with limited interventions that closely related to vascular smooth muscle cell (VSMC) phenotypic switching. SLC44A2, member of the solute carrier series 44 (SLC44) family, remains undercharacterized in context cardiovascular diseases. Venn diagram analysis based on microarray and single-cell RNA sequencing identified SLC44A2 as major regulator VSMC switching aortic aneurysm. Screening for Slc44a2 among lineages demonstrated its predominant...
Aortic aneurysm is a high-risk cardiovascular disease without effective cure. Vascular Smooth Muscle Cell (VSMC) phenotypic switching key step in the pathogenesis of aortic aneurysm. Here, we revealed role histidine triad nucleotide-binding protein 1 (HINT1) HINT1 was upregulated both tissue from patients with and Ang II-induced mice. VSMC-specific deletion alleviated via preventing VSMC switching. With stimulation pathological factors, increased nuclear translocation mediated by nucleoporin...
Active mobilization of repaired flexor tendons requires sufficient suture strength. This study was designed to investigate the suitability four newly developed and comparatively strong tendon sutures for repair with active digital mobilization. Fifty fresh digitorum profundus were randomly assigned five groups using Tang, cruciate, Robertson, Silfverskiold, modified Kessler methods. The subjected mechanical testing in an Instron tensile machine determine 2-mm gap formation force, ultimate...
Recently, the differences in age or sex of deep vein thrombosis (DVT) patients have been widely debated. However, close analyses limb, and Chinese DVT scarcely reported. The purpose this research is to study patients.A total 783 consecutive were retrospectively reviewed. Patients with an acute presentation diagnosed by means compression ultrasonography venography. Clinical characteristics provoked risk factors analyzed.There three frequency peaks including two smaller at 20-24 70-74 years,...
Objective This study aimed to evaluate the potential role of whole-exome sequencing (WES) technique in screening pathogenic genes non-cirrhotic and non-malignant portal vein thrombosis (PVT) clinical efficacy AngioJet-assisted pharmacomechanical thrombectomy (PMT) with transjugular intrahepatic portosystemic stent shunt (TIPS) treat this disease. Methods 16 patients acute PVT were retrospectively analyzed. 14 received genetically diagnosed using WES technique, ten PMT or without TIPS 6 cases...
To evaluate the safety and efficacy of percutaneous closure (PC) using modified double-disc ventricular septal defect (VSD) occluders in patients with ruptured sinus Valsalva aneurysm (RSVA).Between 2005 2012, 25 were enrolled our study for attempted PC. There five (20%) RSVA combined VSD two (8%) aortic regurgitation (AR). The median age was 45 years (24-74 years). QP/QS 2.4±0.6 (1.6-4.0). diameter lesions 6 mm (4-8 mm) while size 8 (6-12 mm). Twenty-three (92%) underwent PC successfully....
Abstract Rationale: Full-thickness wound dehiscence with cerebrospinal fluid (CSF) leakage following posterior spine surgery is a rare but troublesome complication. In the present study, 3 clinical cases associated this entity are reported. Patient concerns: The first case developed incision effusion 5 days after decompression and internal fixation for lumbar spinal stenosis. second has same diagnosis treatment case. She intraoperative CSF leak 7 surgery. third 6 single door laminoplasty...
To evaluate right iliac vein and left compression in asymptomatic subjects, right-sided left-sided iliofemoral deep thrombosis patients.A retrospective analysis of records computed tomography images was conducted 200 subjects (male:female, 100:100). A prospective 79 consecutive patients (left:right thrombosis, 47:32) who had undergone contrast-enhanced examination. The minor diameter percentage the were evaluated.In 13.5% >50%, 2.0% >70%, mean 23.48%; 45.0% >50% 17.0% 47.58%. Right...
G-CSF and EPO have shown a notable capability in neovascularization. However, their use is limited because of untoward leucocytosis, erythrogenesis, short half-life the plasma. Herein, we examined whether released from fibrin gel injected into ischemic tissues would synergistically promote neovascularization with systematic effects rat hindlimb model.In vivo study, group Gel received an intramuscular injection gel; Gel+G-CSF containing human G-CSF; Gel+EPO EPO; Gel+G-CSF&EPO G-CSF&EPO EPO....
Abstract Wrist biomechanics after luno‐triquetral (LT) dissociation is important for understanding the clinical sequelae of disease and determining its treatment options. The LT interosseous ligament plays an role in stabilizing joint damage to would be expected significantly increase moment arms tendon flexor carpi ulnaris (FCU), principal ulnar wrist flexor. We investigated changes FCU various amounts sectioning ligaments proven associated with dissociation. In six fresh frozen cadaveric...
Background and objectives Wall shear stress plays a critical role in neointimal hyperplasia after stent implantation. It has been found that there is an inverse relation between wall hyperplasia. This study hypothesized the increase of arterial caused by arteriovenous fistula could reduce stents Methods results Thirty-six male rabbits were randomly divided into three groups: STENT, received implantation right common carotid artery; STENT/arteriovenous fistula, artery carotid-jugular fistula;...
Objective: There is widespread concern that large-scale insurance expansion - such as anticipated from the Affordable Care Act has potential to cause sharp increases in health care utilization and costs. In setting of Massachusetts’ landmark 2006 reform, we estimated pre-reform post-reform changes inpatient volumes costs, contrasting experience safety-net hospitals (SNH) predominant providers for targeted reform beneficiaries, with non-SNH. Study Design: We analyzed MA discharge on all...
Objective: Percutaneous coronary intervention (PCI) and artery bypass graft (CABG) are documented to be used less often among racial/ethnic minorities. Insurance coverage expansions, such as the 2006 Massachusetts (MA) reform 2010 Affordable Care Act, have potential reduce disparities in access health care. Using quasi-experimental setting of MA reform, we examined causal impact expansion on use elective non-elective PCI CABG. Study Design: We applied a difference-in-differences design for...