A5070482566- Oral microbiology and periodontitis research
- Gut microbiota and health
- Oral Health Pathology and Treatment
- HIV/AIDS oral health manifestations
- Dental Health and Care Utilization
- Salivary Gland Disorders and Functions
- Oral and gingival health research
- Streptococcal Infections and Treatments
- Dental Research and COVID-19
- Periodontal Regeneration and Treatments
- Nutritional Studies and Diet
- Spaceflight effects on biology
- Dental Radiography and Imaging
- Dental Implant Techniques and Outcomes
- High Altitude and Hypoxia
- Hepatitis B Virus Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Electrospun Nanofibers in Biomedical Applications
- Rabies epidemiology and control
- Antimicrobial Resistance in Staphylococcus
Universidade do Estado do Rio de Janeiro
2025
Universidade Federal do Rio de Janeiro
2014-2024
Universidade Federal do Estado do Rio de Janeiro
2022
Abstract Aim To determine microbial profiles that discriminate periodontal health from different forms of diseases. Methods Subgingival biofilm was obtained patients with (27), gingivitis (11), chronic periodontitis (35) and aggressive (24), analysed for the presence >250 species/phylotypes using HOMIM . Microbial differences among groups were examined by Mann–Whitney U ‐test. Regression analyses performed to risk indicators disease. Results Putative potential new pathogens more prevalent...
The oral-gut axis may be a route linking periodontal and systemic diseases. Probiotics could an alternative for the treatment of microbial dysbiotic conditions, including periodontitis. This randomized placebo-controlled clinical trial evaluated short-term efficacy probiotics adjunctive to subgingival instrumentation (SI) in promoting better restoration microbiotas greater outcome.Systemically healthy adults with untreated periodontitis were recruited from Dental School setting allocated...
The dysbiotic biofilm of periodontitis may function as a reservoir for opportunistic human pathogens clinical relevance. This study explored the virulence and antimicrobial susceptibility staphylococci isolated from subgingival individuals with different periodontal conditions. Subgingival was obtained 142 health, 101 gingivitis 302 periodontitis, cultivated on selective media. Isolated strains were identified by mass spectrometry. Antimicrobial determined disk diffusion. mecA genes surveyed...
Oral lichen planus (OLP) is a chronic Th1-mediated inflammatory mucocutaneous disease of the skin and oral mucosa that can have various clinical presentations. Lesions are usually bilateral often painful. While cutaneous Lichen Planus (LP) lesions self-limiting, rarely remissive. The diagnosis challenging, confirmation by histopathological criterion generally advised. aim our study was to identify cytokines present in OLP-suggestive non-specific (NSIL) used as controls. Moreover, assess...
This investigation explored oral-gut microbial signatures with potential to distinguish among periodontal conditions.The interplay between the oral and gut microbiomes may be a critical pathway linking diseases systemic inflammatory disorders. The mechanisms by which microorganisms translocate cause dysbiosis, favoring an state, are still unknown. As first approach, characterization of profiles associated health can provide insights on such etiology pathogenesis.Fecal saliva samples from...
Based on a holistic concept of polymicrobial etiology, we have hypothesized that putative and candidate periodontal pathogens are more frequently detected in consortia than alone advanced forms diseases (PD). Objective To correlate specific with clinical status severity periodontitis. Methodology Subgingival biofilm was obtained from individuals health (113, PH), gingivitis (91, G), periodontitis (209, P). Genomic DNA purified the species Aggregatibacter actinomycetemcomitans (Aa), Aa...
Evidence suggests that translocation of oral pathogens through the oral-gut axis may induce intestinal dysbiosis. This study aimed to evaluate impact a highly leukotoxic Aggregatibacter actinomycetemcomitans (Aa) strain on gut microbiota, mucosal integrity and immune system in healthy mice.
Background: Non-human primates appear to represent the most faithful model of human disease, but date oral microbiome in macaques has not been fully characterized using next-generation sequencing. Objective: In present study, we clinical and microbiological features naturally occurring periodontitis non-human (Macaca mulatta). Design: Clinical parameters including probing pocket depth (PD) bleeding on (BOP) were measured 40 adult (7-22 yrs), at six sites per tooth. Subgingival plaque was...
Abstract Guided tissue regeneration is a technique used for periodontium reconstruction. This uses barrier membranes, which prevent epithelial growth in the wound site and may also be to release antibiotics, protect against opportunistic infections. Periodontal poly(3‐hydroxybutyrate) membranes containing metronidazole (a drug help infection control) were produced characterized. The kinetic mechanism of delivery leached nonleached membrane as well its cytotoxicity structural integrity...
This study evaluates the antimicrobial susceptibility and composition of subgingival biofilms in generalized aggressive periodontitis (GAP) patients treated using mechanical/antimicrobial therapies, including chlorhexidine (CHX), amoxicillin (AMX) metronidazole (MET). GAP allocated to placebo (C, n = 15) or test group (T, 16) received full-mouth disinfection with CHX, scaling root planning, systemic AMX (500 mg)/MET (250 mg) placebos. Subgingival plaque samples were obtained at baseline, 3,...
Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome inflammatory responses. Seven expeditioners took part in a 7-week summer camp (Nelson Island) were evaluated at Pre-Camp (i.e., beginning ship travel), Camp-Initial 4th 5th day camp), Camp-Middle 19th-20th, 33rd-34th days), Camp-Final 45th-46th day), Post-Camp (on ship). At Pre-Camp, Camp-Initial,...
To evaluate the colonization dynamics of subgingival microbiota established over six months around newly installed dental implants in periodontally healthy individuals, compared with their corresponding teeth.Seventeen individuals assigned to receive single participated study. Subgingival biofilm was sampled from all implant sites and contralateral/ antagonist teeth on days 7, 30, 90, 180 after installation. Microbiological analysis performed using Checkerboard DNA-DNA hybridization...
Introduction: The oral microbiota has approximately 700 symbiotic microorganisms responsible for health homeostasis. However, changes in can generate dysbiotic processes that favor the worsening of infections such as caries and periodontal disease. These infections, addition to systemic involvement, compromise teeth integrity well health. Thus, inadequate nutrition proves be a risk factor influencing prevention treatment these infections. Objective: This study aims evidence nutritional...
ABSTRACT Osseointegrable dental implants are biomaterials made of titanium or other alloys mixed with titanium, which have high biocompatibility and allow osseointegration. However, this process can be modulated by changes in the complex mechanisms between microbiota, immune response host. The present study aims to how system-microbiota-host interaction influences osseointegration its alloys. A literature review was performed through electronic manual searches several databases, including...
To evaluate the adjunctive use of probiotic Bifidobacterium animalis subsp. lactis HN019 (B. HN019) to conventional therapy on clinical and microbiological parameters in patients with generalized gingivitis.
A microbiota oral em condições de saúde está equilíbrio entre hospedeiro e microrganismos, porém diversos fatores podem levar ao desequilíbrio dessa relação, associada desenvolvimento progressão doenças orais, como as periodontais (DP). O controle mecânico químico do biofilme dental é o principal método prevenção tratamento dessas doenças, muitas vezes somado uso antimicrobianos. Considerando a atual preocupação sobre indiscriminado antimicrobianos natureza disbiótica da DP, estratégias...