- Air Quality and Health Impacts
- Dental Implant Techniques and Outcomes
- Immune Response and Inflammation
- Occupational exposure and asthma
- NF-κB Signaling Pathways
- Noise Effects and Management
- Peroxisome Proliferator-Activated Receptors
- Inhalation and Respiratory Drug Delivery
- Essential Oils and Antimicrobial Activity
- Orthodontics and Dentofacial Orthopedics
- Oral microbiology and periodontitis research
- Climate Change and Health Impacts
- Vitamin C and Antioxidants Research
- Asthma and respiratory diseases
- Lipoproteins and Cardiovascular Health
- S100 Proteins and Annexins
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- HIV/AIDS oral health manifestations
- Aquatic Ecosystems and Phytoplankton Dynamics
- Energy and Environment Impacts
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Oral and gingival health research
- Vehicle emissions and performance
Universidade Federal do Rio de Janeiro
2008-2023
Czech Academy of Sciences, Institute of Biophysics
2011
The ecological diversity of the periodontal microenvironment may provide suitable conditions for colonization species not usually considered members oral microbiota. In this investigation, we aimed to determine prevalence and levels pathogenic medical relevance in microbiota individuals with distinct clinical status. Subgingival biofilm was obtained from patients health (H, n = 81), gingivitis (G, 55), generalized aggressive (AgP, 36) or chronic periodontitis (CP, 98), analyzed 39 microbial...
Air pollution is associated with morbidity and mortality induced by respiratory diseases. However, the mechanisms therein involved are not yet fully clarified. Thus, we tested hypothesis that a single acute exposure to low doses of fine particulate matter (PM2.5) may induce functional histological lung changes unchain inflammatory oxidative stress processes. PM2.5 was collected from urban area São Paulo city during 24 h underwent analysis for elements polycyclic aromatic hydrocarbon...
Eugenol, a methoxyphenol component of clove oil, suppresses cyclooxygenase-2 expression, while eugenol dimers prevent nuclear factor-kappaB (NF-kappaB) activation and inflammatory cytokine expression in lipopolysaccharide-stimulated macrophages. Our aim was to examine the vivo anti-inflammatory effects eugenol. BALB/c mice were divided into four groups. Mice received saline [0.05 ml intratracheally (it), control (Ctrl) (Eug) groups] or Escherichia coli LPS (10 microg it, LPSEug groups)....
The dysbiotic biofilm of periodontitis may function as a reservoir for opportunistic human pathogens clinical relevance. This study explored the virulence and antimicrobial susceptibility staphylococci isolated from subgingival individuals with different periodontal conditions. Subgingival was obtained 142 health, 101 gingivitis 302 periodontitis, cultivated on selective media. Isolated strains were identified by mass spectrometry. Antimicrobial determined disk diffusion. mecA genes surveyed...
Statins are standard therapy for the treatment of lipid disorders, and field redox biology accepts that statins have antioxidant properties. Our aim in this report was to consider pleiotropic effects atorvastatin, pravastatin simvastatin administered prior endotoxin-induced acute lung injury. Male mice were divided into 5 groups intraperitoneally injected with LPS (10 mg/kg), plus atorvastatin mg/kg/day; A + group), (5 P group) or (20 S group). The control group received saline. All...
Environmentally relevant doses of inhaled diesel particles elicit pulmonary inflammation and impair lung mechanics. Eugenol, a methoxyphenol component clove oil, presents in vitro vivo anti-inflammatory antioxidant properties. Our aim was to examine possible protective role eugenol against injuries induced by particles. Male BALB/c mice were divided into four groups. Mice received saline (10 μl in; CTRL group) or 15 μg DEP (15 DIE DEUG groups). After 1 h, μl; groups) (164 mg/kg; EUG gavage....
A sinvastatina é um medicamento amplamente utilizado no tratamento de dislipidemias, particularmente para reduzir os níveis elevados colesterol LDL e prevenir doenças cardiovasculares, como infarto do miocárdio acidente vascular cerebral. Pertence à classe das estatinas, que agem inibindo a enzima HMG-CoA redutase, responsável pela síntese fígado. Objetivo: Avaliar efeitos da agente osteoindutor em enxertos ósseos reabilitação com implantes dentários. Metodologia: Esta revisão literatura foi...
The aim of the present study was to investigate involvement oxidative stress in acute lung injury (ALI) induced by lipopolysaccharide (LPS) and its effects upon cell structure, function inflammation. In total, 108 male C57BL/6 mice were divided into seven groups: CTR Group (50 µL saline) administered intratracheally (i.t.), LPS 6 h (10 µg − i.t.), 12 24 48 i.t.) + NAC 40 mg/kg (gavage) 100 (gavage). antioxidant treatment protected lungs from first h, but significant induction observed at...
BALB/c mice received saline (SAL groups) or ovalbumin (OVA intraperitoneally (days 1, 3, 5, 7, 9, 11 and 13). After 27 days, a burst of intratracheal OVA SAL 40, 43 46) was performed. Animals were then divided into four groups (N=8, each) intranasally instilled with (SAL-SAL OVA-SAL) residual oil fly ash (SAL-ROFA OVA-ROFA). 24h later, total, initial difference resistances (Rtot, Rinit, Rdiff) static elastance (Est) measured. Lung responsiveness to methacholine assessed as slope sensitivity...
Esse artigo buscou demonstrar, através de um relato caso clínico, a abordagem levantamento seio maxilar bilateral por duas diferentes técnicas, uma traumática via janela lateral e atraumática da crista óssea, associadas à instalação implantes osseointegrados. Paciente com 75 anos, gênero feminino procurou atendimento na clínica do Curso Extensão em Implantodontia universidade Rio Janeiro quadro álgico região molares superiores. Após anamnese, exame clínico análise tomografia computadorizada,...