A5112890524- Liver Disease Diagnosis and Treatment
- MRI in cancer diagnosis
- Liver Disease and Transplantation
- Fibroblast Growth Factor Research
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Cell death mechanisms and regulation
- Frailty in Older Adults
- Sepsis Diagnosis and Treatment
- Nutrition and Health in Aging
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- Bone and Dental Protein Studies
- Pneumonia and Respiratory Infections
- Epigenetics and DNA Methylation
- Alcohol Consumption and Health Effects
- Cancer Research and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Prostate Cancer Diagnosis and Treatment
- Bone health and treatments
- Hedgehog Signaling Pathway Studies
- Galectins and Cancer Biology
- Mycobacterium research and diagnosis
Shandong University
2012-2025
Shandong First Medical University
2019-2025
Tianjin Medical University General Hospital
2020-2025
Shandong Provincial Hospital
2014-2025
Sichuan University
2025
East China Normal University
2025
Tianjin University
2025
Guangdong Province Women and Children Hospital
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Percutaneous coronary intervention (PCI) is a practical and effective method for treating heart disease (CHD). This study aims to explore the influencing factors of major cardiovascular events (MACEs) hospital readmission risk within one year following PCI treatment. Additionally, it seeks assess clinical value Apolipoprotein B/Apolipoprotein A-I (ApoB/ApoA-I) in predicting one-year MACEs post-PCI. A retrospective included 1938 patients who underwent treatment from January 2010 December 2018...
Background Secreted protein acidic and rich in cysteine (SPARC), a calcium-binding matricellular glycoprotein, is implicated the progression of many cancers. In this study, we investigated expression function SPARC ovarian cancer. Methods cDNA microarray analysis was performed to compare gene profiles highly invasive low subclones derived from SKOV3 human cancer cell line. Immunohistochemistry (IHC) staining investigate total 140 tissue specimens. functional assays, effects knockdown on...
Background and Aims: Tongxinluo (TXL) is a multifunctional traditional Chinese medicine that has been widely used to treat cardiovascular cerebrovascular diseases. However, no studies have explored whether TXL can protect human cardiomyocytes (HCMs) from ischemia/reperfusion (I/R) injury. Reperfusion Injury Salvage Kinase (RISK) pathway activation was previously demonstrated the hearts against I/R injury it generally activated via Akt or (and) Erk 1/2, their common downstream protein,...
Abstract Background The administration of levosimendan prophylactically to patients undergoing cardiac surgery remains a controversial practice, and few studies have specifically assessed the value this approach in pediatric patients. This study therefore sought explore safety efficacy prophylactic as means preventing low output syndrome (LCOS) based upon hemodynamic, biomarker, pharmacokinetic readouts. Methods was single-center, double-blind, randomized, placebo-controlled trial. Patients...
Alterations in body compositions are related to poor outcomes and the presence of complications cirrhosis. However, no predictive tools combining all these anthropometric parameters applicable clinical setting. We aimed clarify potential utility develop a nomogram incorporating any independent factor for prognosticating long-term mortality cirrhosis.A total 414 patients were randomized into primary (n = 274) validation 140) cohorts. X-tile was performed identify optimal cut points...
This study aimed to determine the impact of co-infection Clonorchis sinensis (CS) and hepatitis B virus (HBV) on prognosis patients with hepatocellular carcinoma (HCC) following hepatectomy.The clinicopathological information 946 HCC hepatectomy was retrospectively analyzed. The were divided into four groups depending whether they had CS infection and/or HBV infection: double-negative group (infected neither nor HBV), simple only CS), double-positive (co-infected HBV). Kaplan-Meier curves...
Background Reference intervals of Liver function tests are very important for the screening, diagnosis, treatment, and monitoring liver diseases. We aim to establish common reference specifically Chinese adult population. Methods A total 3210 individuals (20–79 years) were enrolled in six representative geographical regions China. Analytes ALT, AST, GGT, ALP, protein, albumin bilirubin measured using three analytical systems mainly used The newly established based on results traceability or...
Abstract Background Although early ambulation (EA) is associated with improved outcomes in post-operative patients, implementation of EA elderly patients still a challenge. In this study, we aimed to design and assess precision program for cardiac rehabilitation. Methods We conducted single-center, randomized controlled clinical trial aged over 60 years after off-pump coronary artery bypass graft (OPCABG) surgery. Patients were randomly assigned (PEA) group or routine (Control) group....
China has a complex geographical environment, and in order to improve the combustion emissions performance of heavy-duty diesel engines operating at low temperatures, low-speed low-load conditions, cleaner mode been proposed. This study utilizes multi-cylinder engine environmental chamber test bench CONVERGE 3D simulation software examine effects intake temperature, injection timing, pressure on emissions. The results indicate that increasing temperature 322 K, advancing timing 1 deg raising...
The combination of Syto16/7-AAD allows the detection apoptosis at an earlier stage than that annexin V/7-AAD. effects spermatozoa on fertilization rate and post-embryonic development have not been investigated systematically. objective this study is to assess relationship between in IVF patients seminal parameters (concentration morphology), effect ART outcomes, especially with regard clinical pregnancy. was detected by syto16/7AAD using flow cytometry (FCM) 98 couples (98 IVF) before after...
Estrogen is the main female hormone of women. It has diverse effects on cell growth, differentiation and homeostatic functions. Accumulated evidence indicated that estrogen may regulate multiple immune functions status However, there little report effect mature B In this study, we observed 17β-estradiol (E2) proliferation, apoptosis, antibody production splenic cells mice in vitro. Splenocytes BALB/c were isolated cultured with E2. E2 treatments decreased expression CD80 molecule but...
This study investigates the effect of glucose on LPS-induced apoptosis dendritic cells in intestinal tract mice and cell line DC2.4. Flow cytometry was used to detect both vivo vitro. Hoechst 33258 staining morphological changes characteristic apoptotic nuclei. Expression related proteins investigated by western blot analysis immunohistochemistry. Pretreatment with a high concentration increased LPS-treated vitro at 24 h. No evident earlier time points 15 min 6 h Furthermore, hours...