- Sexual function and dysfunction studies
- Sexuality, Behavior, and Technology
- Hormonal and reproductive studies
- Genital Health and Disease
- Urinary Bladder and Prostate Research
- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- Sexual Differentiation and Disorders
- Reproductive tract infections research
- Neuropeptides and Animal Physiology
- Urologic and reproductive health conditions
- Sperm and Testicular Function
- Pelvic floor disorders treatments
- Cancer-related gene regulation
- Cancer, Lipids, and Metabolism
- Hypothalamic control of reproductive hormones
- Marriage and Sexual Relationships
- Testicular diseases and treatments
- Mobile Health and mHealth Applications
- Gut microbiota and health
- Obsessive-Compulsive Spectrum Disorders
- Sleep and Wakefulness Research
- Female Genital Mutilation/Cutting Issues
- Genetic Associations and Epidemiology
First Affiliated Hospital of Anhui Medical University
2013-2025
Anhui Medical University
2015-2025
Huazhong Agricultural University
2009-2025
Shanghai Zhangjiang Laboratory
2025
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Northwest Women's and Children's Hospital
2024
Guilin Medical University
2023
State Key Laboratory of Oral Diseases
2021
Sichuan University
2021
Death anxiety is a common phenomenon in all societies. Older adults may be more prone to death than their younger counterparts; however, among older not well understood. This study explores the relationship between meaning life, self-esteem, and senior citizens China.A total of 283 participated this study; data were collected via Meaning Life Questionnaire, Rosenberg Self-Esteem Scale, Anxiety Scale.Results show that dimensions presence (r = - 0.43, p < 0.01), search for 0.31, self-esteem...
The global shortage of high-quality forage has significantly constrained the development animal husbandry. Leveraging complementary effects rapeseed and hairy vetch intercropping can enhance yield quality; however, underlying mechanisms overyielding in rapeseed–hairy systems remain unclear. Over two years field experiments, three cropping systems—rapeseed sole cropping, intercropping—were investigated to assess on root stem morphology, canopy light distribution, leaf photosynthetic...
This study tested a mobile health (mHealth) intervention program entitled WeTest, delivered via the WeChat app, to promote oral HIV self-testing (HIVST) among MSM in Hefei, China. A total of 100 participants enrolled, completed baseline assessment, were randomly assigned or control, and 6-month follow-up surveys. Intervention (n = 50) received two HIVST kits access private group which provided app-based messages referrals services related HIV. Control only. All instructions upload...
HIV self-testing (HIVST) has demonstrated potential to expand testing among key populations, including men who have sex with (MSM) in China low rates. However, due the autonomous nature of self-testing, people undergo HIVST may lack access relevant information and counseling support typically provided by in-person counselors. WeChat, a popular smartphone application China, offers source mobile health (mHealth) for individuals using HIVST. This paper aimed explore opinions MSM about...
The purpose of this study is to investigate the effects adult male circumcision on premature ejaculation (PE). Therefore, between December 2009 and March 2014, a total 575 circumcised men 623 uncircumcised (control group) were evaluated. Detailed evaluations (including control groups) PE conducted before at 3-, 6-, 9-, 12-month follow-up visits after circumcision. Self-estimated intravaginal ejaculatory latency time (IELT), Patient-Reported Outcome measures, 5-item version International...
Tumor protein p53 (TP53) is the most frequently mutated gene in head and neck squamous cell carcinoma (HNSC), TP53 mutations are associated with inhibited immune signatures poor prognosis. We established a mutation risk score model to evaluate prognosis therapeutic responses of patients HNSC.Differentially expressed genes between without were determined by using data from HNSC cohort The Cancer Genome Atlas database. Patients divided into high- low-risk groups based on prognostic that was...
Explore the causal relationship between gut microbiota and erectile dysfunction (ED) at phylum, class, order, family, genus levels, identify specific pathogenic bacteria that may be associated with onset progression of ED.
Abstract Background Erectile dysfunction (ED) is a common condition affecting millions of men worldwide. While genome‐wide association studies (GWAS) have identified genetic loci associated with ED risk, the potential causative genes and their biological mechanisms leading to remain largely unexplored. Objectives This study aimed conduct comprehensive cross‐tissue transcriptome‐wide (TWAS) identify susceptibility risk. Materials methods We conducted TWAS analysis integrating GWAS data for...
Mitochondrial dysfunction may impact male erectile function, but the underlying genetic mechanisms remain unclear. The study aims to investigate causal role for genetically regulated mitochondrial function in (ED) and identify potential drug targets treatment of ED.
Purpose: We developed a nomogram to predict the possibility of lymph node metastasis in patients with squamous cell carcinoma penis. Methods: Identifying penis diagnosed between 2004 and 2015 Surveillance, Epidemiology, End Results (SEER) database. Univariate multivariate analyses were carried out by logistic regression assess significant predictors associated metastasis. A was established validated calibration plot receptor operating characteristic curve (ROC) analysis. Results: total 1,016...
Background Previous research has shown that testosterone deficiency (TD) increases the risk of anemia, but it is unclear whether anemia affects levels. This study investigated influence on
Abstract Background Sleep deprivation (SD) can cause damage to the male reproductive system. However, duration required for such and specific sequence severity of testis epididymis remain unclear. Objective To investigate effects different durations SD on parts caput, corpus, cauda. Methods Adult ICR mice were randomly assigned five groups: group (SD 18 h/day 1, 2, 3, or 4 weeks), + Vit E (supplemented with 50 mg/kg/d during weeks SD, SD+NS (saline supplementation SD), RS (5 recovery sleep...
BACKGROUND The STin2 VNTR polymorphism has a variable number of tandem repeats in intron 2 the serotonin transporter gene. We aimed to explore relationship between and lifelong premature ejaculation (LPE). MATERIAL AND METHODS recruited total 115 outpatients who complained ejaculating prematurely were diagnosed as LPE, 101 controls without PE complaint. Allelic variations genotyped using PCR-based technology. evaluated associations allelic genotypic frequencies well intravaginal latency time...
BACKGROUND:This study aimed to explore the relationship between premature ejaculation (PE) and serotonin transporter gene-linked polymorphic region (5-HTTLPR) with respect biallelic triallelic classifications. MATERIAL AND METHODS:A total of 115 outpatients who complained ejaculating prematurely were diagnosed as having lifelong (LPE) 101 controls without PE complaint recruited. All subjects completed a detailed questionnaire genotyped for 5-HTTLPR polymorphism using PCR-based technology. We...
Few studies have explored the optimal examined lymph node count and density cutoff values that could be used to predict survival of patients with penile cancer. We further clarify prognostic value in cancer.The Surveillance, Epidemiology, End Results (SEER) database was recruit cancer from 2010 2015. A retrospective analysis patients' data First Affiliated Hospital Anhui Medical University performed for verification (2006-2016). The were according ROC curve. Kaplan-Meier compare differences...
Although there was some evidence to suggest that the serotonergic system in brain played an important role premature ejaculation (PE), tryptophan hydroxylase-2 (TPH2) is considered be key enzyme for synthesis of 5-hydroxytryptamine (5-HT) and few studies have reported TPH2 involved regulation ejaculation.This study aimed investigate whether changes levels were associated with PE explore effects acute administration dapoxetine on expression rats rapid ejaculation.Based frequency, male split...