A5028980122- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
- Hormonal and reproductive studies
- Sexuality, Behavior, and Technology
- Genital Health and Disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pelvic floor disorders treatments
- Urologic and reproductive health conditions
- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Lysosomal Storage Disorders Research
- Mitochondrial Function and Pathology
- Obsessive-Compulsive Spectrum Disorders
- Neuroscience and Neuropharmacology Research
- Complex Network Analysis Techniques
- Opinion Dynamics and Social Influence
- Psoriasis: Treatment and Pathogenesis
- Sperm and Testicular Function
- Cancer-related molecular mechanisms research
- Female Genital Mutilation/Cutting Issues
- Marriage and Sexual Relationships
- Spondyloarthritis Studies and Treatments
- Ion Transport and Channel Regulation
- Testicular diseases and treatments
- Adolescent Sexual and Reproductive Health
First Affiliated Hospital of Anhui Medical University
2016-2025
Anhui Medical University
2016-2025
Gilead Sciences (United States)
2019-2025
Fujian Medical University
2017-2025
Zhejiang Chinese Medical University
2024
Xinxiang Medical University
2019-2024
China Meteorological Administration
2023-2024
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2024
Beijing Meteorological Bureau
2024
University of Science and Technology Beijing
2024
Parthenolide (PTL) is a natural molecule isolated from Tanacetum parthenium that exhibits excellent anti-inflammatory and antitumor activities. Pulmonary fibrosis (PF), especially idiopathic pulmonary (IPF), chronic lung disease lacks proven effective therapy. The present study evaluated the therapeutic effect of PTL on PF. Serum-starved primary fibroblasts HFL1 cells were treated with different doses PTL, cell viability migration rate measured. Western blot analysis dual-luciferase assay...
Idiopathic pulmonary fibrosis (IPF) is a progressive and usually fatal lung disease that characterized by fibroblast proliferation extracellular matrix remodeling, which result in irreversible distortion of the lung's architecture formation focal fibrous hyperplasia. The molecular mechanism develops not fully understood, no satisfactory treatment currently exists. However, many studies consider aberrant activation TGF-β1 frequently promotes epithelial-mesenchymal transition (EMT) fibrosis....
Two-dimensional materials represent a major frontier for research into exotic many-body quantum phenomena. In the extreme two-dimensional limit, electron-electron interaction often dominates over other electronic energy scales, leading to strongly correlated effects such as spin liquid and unconventional superconductivity. The dominance is conventionally attributed lack of electron screening in third dimension. Here, we discover an intriguing metal Mott insulator transition 1T-TaSe
Explore the causal relationship between gut microbiota and erectile dysfunction (ED) at phylum, class, order, family, genus levels, identify specific pathogenic bacteria that may be associated with onset progression of ED.
Penile cancer (PeCa) is a relatively rare tumor entity but possesses higher morbidity and mortality rates especially in developing countries. To date, the concrete pathogenic signaling pathways core machineries involved tumorigenesis progression of PeCa remain to be elucidated. Several studies suggested miRNAs, which modulate gene expression at posttranscriptional level, were frequently mis-regulated aberrantly expressed human cancers. However, miRNA profile has not been reported before. In...
Abstract Introduction In 2014, new evidence-based definitions of lifelong premature ejaculation (LPE) and acquired (APE) were proposed by the International Society for Sexual Medicine. Based on PE definitions, prevalence factors associated with LPE APE have not been investigated in China. Aim To evaluate men complaint Methods From December 2011 to 2015, a cross-sectional field survey was conducted five cities Anhui province Questionnaire data 3,579 collected our database. The questionnaire...
The purpose of this study is to investigate the effects adult male circumcision on premature ejaculation (PE). Therefore, between December 2009 and March 2014, a total 575 circumcised men 623 uncircumcised (control group) were evaluated. Detailed evaluations (including control groups) PE conducted before at 3-, 6-, 9-, 12-month follow-up visits after circumcision. Self-estimated intravaginal ejaculatory latency time (IELT), Patient-Reported Outcome measures, 5-item version International...
Imaging through scattering media is valuable for many areas, such as biomedicine and communication. Recent progress enabled by deep learning (DL) has shown superiority especially in the model generalization. However, there a lack of research to physically reveal origin or define boundary scalability, which important utilizing DL approaches scalable imaging despite with high confidence. In this paper, we find amount ballistic light component output field prerequisite endowing generalization...
Abstract Background Erectile dysfunction (ED) is a common condition affecting millions of men worldwide. While genome‐wide association studies (GWAS) have identified genetic loci associated with ED risk, the potential causative genes and their biological mechanisms leading to remain largely unexplored. Objectives This study aimed conduct comprehensive cross‐tissue transcriptome‐wide (TWAS) identify susceptibility risk. Materials methods We conducted TWAS analysis integrating GWAS data for...
Autoimmune haemolytic anaemia (AIHA) is common secondary to diffuse large B-cell lymphoma (DLBCL). However, there are no reports on tumour B-cells differentiating into plasmablasts in DLBCL AIHA. To state impact of the interferon regulatory factor 4 (IRF4) and explore mechanism IRF4 plasmablast differentiation.We analysed expression immunity-related genes from Gene Expression Omnibus correlated predictors clinical laboratory data using R package various statistical tools. Western blotting...
The purpose of this study is to investigate the prevalence rate and risk factors depression in outpatients who were diagnosed with PE. Therefore, between September 2009 2011, 1801 at andrology clinics enrolled consented participate our survey by completed a verbal questionnaire. It included following: (1) demographic data (e.g., age, body mass index), (2) PE duration, medical history, sexual (3) self-estimated intravaginal ejaculatory latency times, (4) Zung Self-rating Depression Scale...
Mitochondrial dysfunction may impact male erectile function, but the underlying genetic mechanisms remain unclear. The study aims to investigate causal role for genetically regulated mitochondrial function in (ED) and identify potential drug targets treatment of ED.