A5000956565- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Pneumonia and Respiratory Infections
- Infectious Diseases and Tuberculosis
- Parasitic Infections and Diagnostics
- Malaria Research and Control
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Epilepsy research and treatment
- Otolaryngology and Infectious Diseases
- Misinformation and Its Impacts
- Public Health Policies and Education
- Hemoglobinopathies and Related Disorders
- Viral Infections and Outbreaks Research
- Immune responses and vaccinations
- Antimicrobial Resistance in Staphylococcus
- HIV/AIDS Impact and Responses
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Global Maternal and Child Health
Johns Hopkins University
2006-2015
McGill University
2005-2012
American College of Chest Physicians
2012
Université de Montréal
2008-2009
Prisma
2006
Universidad Peruana Cayetano Heredia
2004
New diagnostic tools are urgently needed to interrupt the transmission of tuberculosis and multidrug-resistant tuberculosis. Rapid, sensitive detection in sputum has been demonstrated proof-of-principle studies microscopic-observation drug-susceptibility (MODS) assay, which broth cultures examined microscopically detect characteristic growth.In an operational setting Peru, we investigated performance MODS assay for culture testing three target groups: unselected patients with suspected...
OBJECTIVE: To determine whether Bacille Calmette-Guerin (BCG) vaccination is linked to the risk of acute lower respiratory infection (ALRI) among children <5 years age. METHODS: Data from Macro International Demographic and Health Surveys United Nations Children’s Fund Multiple Indicator Cluster were used identify a primary cohort 58 021 in 19 countries (2005–2010) secondary 93 301 18 (2000–2007). Information was collected by trained interviewers during home visits using standardized...
ABSTRACT There is an urgent need for new tools to improve our ability diagnose tuberculosis (TB) and multidrug-resistant TB (MDR-TB) in resource-poor settings. In a retrospective analysis undertaken region with high incidence of TB, we evaluated the performance microscopic observation drug susceptibility assay (MODS), novel developed Perú which uses inverted light microscope culture Middlebrook 7H9 broth detect mycobacterial growth. MODS detected 94.0% 1,908 positive sputum cultures,...
Giardia intestinalis is a common gastrointestinal protozoan worldwide, but its effects on childhood growth in developing countries are not clearly understood. The authors aimed to describe child growth. They followed 220 Peruvian children daily for diarrhea, weekly stool samples, and monthly anthropometry. modeled the effect of nutritional status risk infection diarrhea attributable using negative binomial regression. linear regression, with 85% becoming infected 87% these reinfected. In...
Abstract We identified 306 invasive group A streptococcal infections (IGASI) by passive population-based surveillance in Montreal, Canada, from 1995 to 2001. The average yearly reported incidence was 2.4 per 100,000 persons, with a 14% death rate. Among clinical manifestations, of pneumonia increased 0.06 0.50 2000. Over span 7 years, the odds developing (odds ratio [OR] = 1.21, 95% confidence interval [CI] 1.0–1.5), while they decreased for soft-tissue (OR 0.86, CI 0.7–1.0). Serotypes M1...
Background: Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes.We undertook an individual patient data meta-analysis to assess the impact on outcomes type, number, duration drugs used treat MDR-TB.Methods Findings: Three recent systematic reviews were identify studies reporting treatment microbiologically confirmed MDR-TB.Study authors contacted solicit including clinical characteristics, given, outcomes.Random effects...
Recent studies, partly based on murine models, suggest childhood immunization and vitamin A supplements may confer protection against malaria infection, although strong evidence to support these theories in humans has so far been lacking. We analyzed national survey data from children aged 6-59 months four sub-Saharan African countries over an 18-month time period, determine the risk of Plasmodium spp. parasitemia (n=8390) falciparum HRP-2 (PfHRP-2)-related antigenemia (n=6121) following...