Debora Pezzini
A5064798026- Acute Ischemic Stroke Management
- Long-Term Effects of COVID-19
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- COVID-19 Clinical Research Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Neurological Complications and Syndromes
- COVID-19 and healthcare impacts
- Migraine and Headache Studies
- Neurosurgical Procedures and Complications
- Renal and Vascular Pathologies
- Ion channel regulation and function
- Cervical and Thoracic Myelopathy
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Vascular Anomalies and Treatments
University of Brescia
2020-2024
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2024
Brescia University
2020-2023
Severe hematoma expansion (sHE) has the strongest impact on intracerebral hemorrhage (ICH) outcome. We investigated predictors of sHE.
Background and Purpose: Observational studies have suggested a link between fibromuscular dysplasia spontaneous cervical artery dissection (sCeAD). However, whether patients with coexistence of the two conditions distinctive clinical characteristics has not been extensively investigated. Methods: In cohort consecutive first-ever sCeAD, enrolled in setting multicenter IPSYS CeAD study (Italian Project on Stroke Young Adults Cervical Artery Dissection) January 2000 June 2019, we compared...
To characterize patients with acute ischemic stroke related to SARS-CoV-2 infection and assess the classification performance of clinical laboratory parameters in predicting in-hospital outcome these patients.In setting STROKOVID study including consecutively admitted ten hub hospitals Lombardy, Italy, between March 8 April 30, 2020, we compared features confirmed non-infected by logistic regression models survival analysis. Then, trained tested a random forest (RF) binary classifier for...
Background and purpose Whether the reported association between migraine with aura (MA) cardioembolic stroke may be explained by a higher rate of atrial fibrillation (AF) or other potential cardiac sources cerebral embolism remains to determined. Methods In setting single centre cohort study consecutive patients acute brain ischaemia stratified status, AF as well patent foramen ovale (PFO) was explored. Results all, 1738 (1017 [58.5%] men, mean age 67.9 ± 14.9 years) qualified for analysis....
Objective To explore the impact of antithrombotic therapy discontinuation in postacute phase cervical artery dissection (CeAD) on mid-term outcome these patients. Methods In a cohort consecutive patients with first-ever CeAD, enrolled setting multicentre Italian Project Stroke Young Adults Cervical Artery Dissection, we compared (beyond 6 months since index CeAD) outcomes between who discontinued and continued taking agents during follow-up. Primary was composite ischaemic stroke transient...
Subclinical vascular brain lesions are highly prevalent in elderly patients with stroke. Little is known about predisposing factors and their impact on long-term outcome of stroke at a young age.We quantified magnetic resonance-defined subclinical lesions, including lacunes white matter hyperintensities, perivascular spaces cerebral microbleeds, assessed total small-vessel disease (SVD) score first-ever acute ischemic aged 18 to 45 years, followed them up, as part the multicentre Italian...
The aim of this study is to evaluate the differences in clinical presentations and impact healthcare organization on outcomes neurological COVID-19 patients admitted during first second pandemic waves.In single-center cohort study, we included all with SARS-CoV-2 infection a Neuro-COVID Unit. Demographic, clinical, laboratory data were compared between waves pandemic.Two hundred twenty-three included, whom 112 111 hospitalized waves, respectively. Patients wave younger exhibited pulmonary...
Abstract Whether and how SARS-CoV-2 outbreak affected in-hospital acute stroke care system is still matter of debate. In the setting STROKOVID network, a collaborative project between 10 centers designed as hubs for treatment during in Lombardy, Italy, we retrospectively compared clinical features process measures patients with confirmed infection (COVID-19) non-infected (non-COVID-19) who underwent reperfusion therapies ischemic stroke. Between March 8 April 30, 2020, 296 consecutive...
Abstract Background The role of vaccination on Covid-19 severity in neurological patients is still unknown. We aim at describing clinical characteristics and outcomes breakthrough unvaccinated hospitalized for disorders. Methods Two hundred thirty-two were admitted to a neuro-Covid Unit form March 2021 February 2022. Out the total sample, 74 (32%) full vaccinated. prevalence, final syndromes compared between vaccinated cases. Results Breakthrough cases older (years 72.4 + 16.3 vs 67.0 18.9...
Abstract Objective The aim of this study is to evaluate the differences clinical presentations and impact healthcare organization on outcomes neurological COVID-19 patients admitted during first second pandemic waves. Methods In single center cohort study, we included all with SARS-CoV-2 infection a Neuro-COVID Unit. Demographic, laboratory data were compared between waves pandemic. Results 223 included, whom 112 111 hospitalized waves, respectively. Patients wave younger exhibited pulmonary...