A5002850947- Parkinson's Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Dementia and Cognitive Impairment Research
- Restless Legs Syndrome Research
- Stroke Rehabilitation and Recovery
- Medical Imaging and Analysis
- Neurological disorders and treatments
- Sleep and related disorders
- Spinal Dysraphism and Malformations
- Pain Mechanisms and Treatments
- Spinal Cord Injury Research
- Intraoperative Neuromonitoring and Anesthetic Effects
- Multiple Sclerosis Research Studies
- Dysphagia Assessment and Management
- Machine Learning in Healthcare
- Antiplatelet Therapy and Cardiovascular Diseases
- Health disparities and outcomes
- RNA regulation and disease
- Child Nutrition and Feeding Issues
- COVID-19 and healthcare impacts
- Hereditary Neurological Disorders
- Infectious Encephalopathies and Encephalitis
- Obsessive-Compulsive Spectrum Disorders
- Sleep and Wakefulness Research
- Neurological Disease Mechanisms and Treatments
Korea University Medical Center
2024
Korea University
2024
Dong-A University
2014-2020
No previous studies have investigated the relationship between various anti-ganglioside antibodies and clinical characteristics of Guillain-Barré syndrome (GBS) in Korea. The aim this study was to determine prevalence types Korean GBS patients, identify their significance. Serum collected from patients during acute phase at 20 university-based hospitals laboratory findings were reviewed compared with detected antibody. Among 119 60 positive for immunoglobulin G (IgG) or M against any type...
Autonomic symptoms are commonly observed in patients with Parkinson's disease (PD) and often limit the activities of daily living. The Scale for Outcomes disease-Autonomic (SCOPA-AUT) was developed to evaluate quantify autonomic PD. goal this study translate original SCOPA-AUT, which written English, into Korean its reliability validity PD patients.For translation, following processes were performed: forward backward expert review, pretest pre-final version development final SCOPA-AUT...
Functional outcomes after acute ischemic stroke are of great concern to patients and their families, as well physicians surgeons who make the clinical decisions. We developed machine learning (ML)-based functional outcome prediction models in stroke.This retrospective study used a prospective cohort database. A total 1066 with between January 2019 March 2021 were included. Variables such demographic factors, stroke-related laboratory findings, comorbidities utilized at time admission. Five...
Niemann-Pick disease, type C (NP-C), is caused by NPC1 or NPC2 gene mutations.Progressive neurological, psychiatric, and visceral symptoms are characteristic.Here, we present cases of a brother (Case 1) sister 2) in their mid-20s with gait disturbance psychosis.For the Case 1, neurological examination revealed dystonia, ataxia, vertical supranuclear-gaze palsy (VSGP), global cognitive impairment.Case 2 showed milder, but similar symptoms, cortical atrophy.Abdominal computed tomography...
This study aimed to determine the clinimetric properties of Korean version Parkinson's Disease Sleep Scale-2 (K-PDSS-2) and whether distinct subtypes sleep disturbance can be empirically identified in patients with disease (PD) using cross-culturally validated K-PDSS-2.The internal consistency, test-retest reliability, scale precision, convergent validity K-PDSS-2 were assessed a nationwide, multicenter 122 PD. Latent class analysis (LCA) was used derive subgroups who experienced similar...
Objective The Scales for Outcomes in Parkinson’s Disease–Cognition (SCOPA-Cog) was developed to assess cognition patients with disease (PD). In this study, we aimed evaluate the validity and reliability of Korean version SCOPACog (K-SCOPA-Cog).Methods We enrolled 129 PD movement disorders from 31 clinics South Korea. original SCOPA-Cog translated into using translation-retranslation method. test–retest method an intraclass correlation coefficient (ICC) Cronbach’s alpha were used reliability....
Background: Spinal cord infarction (SCI) is a rare disease and its early diagnosis challenging. Here, we described the clinical features imaging findings of SCI, assessed results evoked potential (EP) studies to elucidate their diagnostic role in stage SCI. Methods: We retrospectively analyzed 14 patients who had spontaneous The demographic, neurological, temporal profiles SCI were identified. reviewed changes them over time. To review EP, central motor conduction time (CMCT) somatosensory...
Background: Sleep problems commonly occur in patients with Parkinson's disease (PD), and are associated a lower quality of life.The aim the current study was to translate English version Scales for Outcomes Disease-Sleep (SCOPA-S) into Korean SCOPA-S (K-SCOPA-S), evaluate its reliability validity use by Korean-speaking PD.Methods: In total, 136 PD from 27 movement disorder centres university-affiliated hospitals Korea were enrolled this study.They assessed using SCOPA, Hoehn Yahr Scale...
Impulse-control disorder is an important nonmotor symptom of Parkinson's disease (PD) that can lead to financial and social problems, be related a poor quality life. A nationwide multicenter prospective study was performed with the aim validating Korean Version Questionnaire for Impulsive-Compulsive Disorders in Disease Rating Scale (K-QUIP-RS).The K-QUIP-RS constructed using forward backward translation, pretesting prefinal version. PD patients on stable medical condition were recruited...
Background and Purpose Few studies of dementia in Parkinson's disease (PD) have had long-term follow-ups.Moreover, information on the duration from onset to development patients with PD is lacking.The aim this study was determine median dementia-free survival time dementia.Methods In total, 1,193 Korean were recruited assessed at regular intervals 3-6 months.We interviewed other informants identify impairments activities daily living.The Hoehn Yahr stage scores Unified Disease Rating Scale...
Abstract The stroke incidence has increased rapidly in South Korea, calling for a national-wide system long-term management. We investigated the effects of socioeconomic status (SES) and geographic factors on chronic phase survival after stroke. retrospectively enrolled 6994 patients who experienced event 2009 from Korean National Health Insurance database. followed them up 24 to 120 months onset. endpoint was all-cause mortality. defined SES using medical-aid group four groups divided by...
Early-onset dementia (EOD) is still insufficiently considered for healthcare policies. We investigated the effect of socio-environmental factors on long-term survival patients with EOD. This retrospective cohort study utilized Korean National Health Insurance Database from 2007 to 2018. enrolled 3,825 aged 40 65 years old all types newly diagnosed in 2009 as EOD cases. defined socioeconomic status using national health insurance premium (NHIP) levels. Residential areas were classified into...
This study aimed to evaluate the behavioral and disease-related characteristics of patients with acute stroke during Coronavirus disease (COVID-19) pandemic. retrospective was conducted using Korean Stroke Registry database from a single cerebrovascular specialty hospital. We categorized COVID-19 pandemic (February 2020 June 2021) into three waves according number cases recorded subjective fear index general population matched them corresponding pre-COVID-19 (January 2019 January 2020)...
Background: Sleep-related disturbances and sleep disorders are common in Parkinson’s disease (PD) have a great impact on daily life of PD patients. This study was done to find the characteristics disturbing factors patients according severity through clinical interview polysomnographic (PSG) study. Methods: Fifty with (22 males, age 60.6 ± 6.4, Hoehn Yahr (HY) stage 2.7 1.0) were recruited thoroughly interviewed about their sleep. PSG performed taking routine antiparkinsonian medications....
Dementia is a key symptom of Parkinson's disease (PD), and influences the patient's quality life caregiver's burden. This study aimed to identify neuropsychological tests mild cognitive impairment (MCI) subtypes that show strong association with conversion from non-demented PD PD-MCI dementia (PDD). Non-demented patients who had undergone comprehensive at baseline were included in this study. We compared data between individuals converted PDD whole cohort, as well those PD-MCI,...
The rapidly increasing socioeconomic strain caused by dementia represents a significant public health concern. Regional centers (RDCs) have been established nationwide, and they aim to provide timely screening diagnosis of dementia. This study investigated the clinical characteristics progression patients diagnosed with Alzheimer's (AD), who underwent treatment in RDCs or conventional community-based hospital systems.This retrospective single-center cohort included were AD between January...
Abstract Although Parkinson’s disease (PD) has a heterogeneous course, it remains challenging to establish subtypes. We described and clustered the natural course of with respect functional disability mortality. This retrospective cohort study utilized Korean National Health Insurance Service database, which contains social support registry database for patients PD. extracted newly diagnosed PD in 2009 followed them up until end 2018. Functional was assessed based on long-term care insurance...