A5102758885- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Advancements in Transdermal Drug Delivery
- Meta-analysis and systematic reviews
- Clinical Laboratory Practices and Quality Control
- Alzheimer's disease research and treatments
- Cholinesterase and Neurodegenerative Diseases
- Phytase and its Applications
- Fatty Acid Research and Health
- Dementia and Cognitive Impairment Research
- Curcumin's Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Natural Antidiabetic Agents Studies
- Fibroblast Growth Factor Research
- Ethics in Clinical Research
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical Practices and Patient Outcomes
- Bee Products Chemical Analysis
- Hemodynamic Monitoring and Therapy
- Iron Metabolism and Disorders
- Cancer, Lipids, and Metabolism
- Proteoglycans and glycosaminoglycans research
- Trace Elements in Health
- Drug-Induced Adverse Reactions
- Surfactants and Colloidal Systems
Institute of Human Behaviour and Allied Sciences
2011-2024
Yashwantrao Chavan Maharashtra Open University
2024
Babasaheb Bhimrao Ambedkar University
2015-2023
National Institute of Technology Jamshedpur
2020-2021
GLA University
2020
Government Medical College Bhavnagar
2011-2016
University of Lucknow
2016
Panjab University
2016
Government Medical College
2014
Gujarat Cancer Society
2014
To find out the most common bacterial pathogens responsible for post-operative wound infection and their antibiotic sensitivity profile.This prospective, observational study was carried in patients of postoperative infection. Samples from discharge were collected using a sterile swab studied identification isolates by Gram stains culture growth followed vitro susceptibility testing performed disc diffusion method on Mueller Hinton agar.Out 183 organisms, 126 (68.85%) isolated organisms gram...
The current studies entail systematic development of self-nanoemulsifying drug delivery systems (SNEDDS) containing medium-chain triglycerides (MCTs) and long-chain (LCTs) for augmenting the biopharmaceutical performance artemether. Equilibrium solubility pseudoternary phase diagram facilitated selection Captex 355 Ethyl oleate as MCTs LCTs, Cremophor RH 40 Tween 80 surfactants, while Transcutol HP cosolvent formulating SNEDDS. Systematic optimization was performed employing Box–Behnken...
To find out incidence of adverse drug reactions (ADR) in patients internal medicine wards and study various aspects ADR, e.g., causality, mortality, drugs commonly causing ADR Guru Gobind Singh Hospital, Jamnagar, a tertiary care hospital.
Gout is a painful disorder which does not have an efficient delivery system for its treatment.Development and in vitro, vivo evaluation of allopurinol-loaded nonionic surfactant-based niosomes was envisaged.Niosomes were prepared with Span 20 Tween (1:1 molar ratio) using ether injection method. The formulations screened entrapment efficiency, particle size analysis, zeta potential, release kinetics, activity, stability studies.Stable, spherical vesicles average 304 nm zeta-potential...
Co-therapy through biotin modified nanoparticles (NPs) of gefitinib (Gnb) and naringenin (Nar) was investigated for its therapeutic synergistic potential against lung cancer. The biotin-conjugated polymeric NPs (bty-Nar/Gnb) were developed using oil in water emulsion technique optimized central composite design. formulations subjected to various vitro (A549 cell lines) vivo evaluations urethane-induced Co-administration Gnb Nar displayed a significant reduction tumour volume while restoring...
To evaluate drug utilization pattern in terms of defined daily dose along with pharmacoeconomic analysis geriatric patients admitted medical ward a tertiary care hospital.Retrospective record was performed for indoor cases the (age ≥65 years) medicine from January 2010 to December were analyzed demographics, indications admission, various systems involved, duration hospital stay, drugs prescribed, and adverse reaction. The categorized by anatomical therapeutic classification calculated....
<i>Gymnema sylvestre</i> R. BR. (Asclepiadaceae) has been used frequently in traditional Indian folk medicine for the treatment of diabetes. Study was performed high fat diet (HFD)-induced obesity murine model. Obesity induced by oral feeding HFD 28 days. The anti effect water soluble fraction extract (120 mg/kg, p.o. 21 days) fed rats evaluated measurement body weight gain, food intake, hemodynamic changes (systolic, diastolic, mean blood pressure and heart rate), serum lipid profiles...
Seven years old male child (24 kg weight) diagnosed as a case of sub acute appendicitis treated with ciprofloxacin, immediately developed multiple erythmatous papules. Reaction subsided after withholding ciprofloxacin and treatment dexamethasone chlorpheneramine maleate. It was again when levofloxacin withdrawal. IgE binding at 7(th) position core structure fluoroquinolones likely to be the mechanism. As all have similar structure, hypersensitivity one may cross sensitivity other...
CSF tau and Aβ42 are considered as important markers to diagnose Alzheimer's disease in early stages. Hence, it is assess their status different types of dementia. The main objective this study was whether these biomarkers can be used make the differential diagnosis AD. In present study, articles published from 1998 till 2009 were taken meta-analysis performed clarify consistency trends biomarkers- Aβ(42) AD other dementias same diagnostic for its diagnosis. 11 out 60 07 40 Aβ(42), dementia...
Inositol hexaphosphate (IP6) is a natural constituent found in almost all cereals and legumes. It known to cause numerous antiangiogenic manifestations. Notwithstanding its great potential, it underutilized due the chelation rapid excretion from body. Jacalin another obtained seeds of jackfruit can target disaccharides overexpressed tumor cells. The current study was in-quested develop evaluate surface-modified gold nanoparticulate system containing IP6 jacalin which may maximize apoptotic...
Use of α-linolenic acid as an oil phase for microemulsion preparation with synergistic effect in lowering lipid levels combination simvastatin.
A 55 years old male patient, who is planned for bronchoscopy developed central anti-cholinergic syndrome due to therapeutic dose of atropine. Withdrawal atropine has improved the symptoms. Thereafter, instillation as eye drops leads reappearance The reaction was definite according Naranjo's algorithm. It severe and definitely preventable Modified Hartwig Siegel's scale Schumock Thornton respectively. Central may be variation in genetic susceptibility (Idiosyncrasy) Idiosyncratic on...