A5066719149- Immunodeficiency and Autoimmune Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pediatric health and respiratory diseases
- Immune responses and vaccinations
- Urological Disorders and Treatments
- Allergic Rhinitis and Sensitization
- Blood disorders and treatments
- Urologic and reproductive health conditions
- Cystic Fibrosis Research Advances
- Urticaria and Related Conditions
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 and COVID-19 Research
- Pediatric Urology and Nephrology Studies
- Drug-Induced Adverse Reactions
- Mast cells and histamine
- Autoimmune Bullous Skin Diseases
- Genital Health and Disease
- Asthma and respiratory diseases
- Immune Cell Function and Interaction
- Renal cell carcinoma treatment
- COVID-19 Clinical Research Studies
- Urinary and Genital Oncology Studies
- Food Allergy and Anaphylaxis Research
- Urinary Bladder and Prostate Research
- Comparative Animal Anatomy Studies
Batman University
2024-2025
Necmettin Erbakan University
2013-2024
Pamukkale University
2023
Konya Eğitim ve Araştırma Hastanesi
2023
ENT and Allergy
2021
Dicle University
2010-2017
Selçuk University
1986-2008
Background: Studies on the impact of comorbidities treatment responses in severe eosinophilic asthma (SEA) are limited. This study was a real-world investigation into how presence or absence nasal polyps (NP) and sensitivity to aeroallergens influence outcomes mepolizumab therapy. Methods: In this retrospective study, data obtained from patients with SEA who received at least 6 months were analyzed. The initially divided two groups based NPs. Within these groups, further categorized...
Background: Selective immunoglobulin E deficiency (sIgED) is a rare condition characterized by low serum IgE levels with normal of other classes. The prevalence sIgED varies considerably across populations, higher observed in clinical settings. Studies report that ranges up to 9.7% patients attending rheumatology clinics, 8.1% allergy/immunology and 2.6% healthy blood donors. Its role immune regulation association autoimmune autoinflammatory disorders remains poorly understood. Objective:...
The aim of this study was to investigate the relationship B cell-mediated immunity with disease severity and mortality in patients COVID-19.In retrospective cohort single-centre study, 208 laboratory-confirmed COVID-19 were recruited. A score, ranging from 0 10, used evaluate associations between various factors. Serum immunoglobulin levels number cells lymphocyte subsets measured their association examined.The median age 50 (35-63) years 88 (42%) female. deceased 17. score 8 (6-8) 1 (0-2)...
There is no definite information about the tongue morphology of blind mole rats owing to spreading these animals only a certain habitat. For this reason, we aimed examine morphological structure by scanning electron microscopy (SEM) in species. In study, tongues four were used and its lingual surface, different types papillae, their characteristics topographical distribution was described. Three papillae (filiform, fungiform vallate) prominence observed. The dorsal surface covered filiform...
We studied the use of magnetic resonance imaging in diagnosis penile fracture.Between 1997 and 2012, fifteen patients (age range 17-48 years, mean age 37 years) with suspected fracture underwent MRI examinations. Ten were injured during sexual intercourse, whereas four traumatized by non-physiological bending penis self manupilation, one patient was falling from bed. Investigations performed 1.5 T MR unit. With supine position, taped against abdominal wall surface coil placed on penis. All...
Objective: This study investigates the prevalence of Common Variable Immunodeficiency (CVID) in patients with cryptogenic cirrhosis. It aims to highlight CVID's role liver involvement and raise awareness its potential as an underlying cause Methods: retrospective cohort study, approved by ethics committee, included diagnosed cirrhosis at a university hospital. Comprehensive evaluations were performed exclude other causes cirrhosis, screened for CVID based on European Society...
Background: Omalizumab is a preferred treatment in antihistamine-refractory chronic spontaneous urticaria (CSU) patients. However, factors that may impact response remain to be explored. Objective: This study aimed examine the affecting CSU patients receiving omalizumab. Methods: was retrospective included 123 who received omalizumab for between January 2015 and April 2024. After administering omalizumab, we evaluated therapeutic efficacy with control test (UCT). According UCT, were...
Abstract Background/Aims: Hereditary angioedema (HAE) is a rare genetic disorder (prevalence approximately 1:50,000) marked by recurrent episodes of severe swelling due to deficiency in the C1 inhibitor (C1-INH) protein, affecting complement and contact systems. This study aims evaluate impact Prognostic Nutritional Index (PNI) on clinical outcomes HAE patients. Methods: A single-center retrospective cohort 60 patients was analyzed. Clinical characteristics PNI were assessed, calculated...
Primary immunodeficiency diseases (PIDs) show different patterns of airway involvement, particularly bronchiectasis; however, comparative studies radiologic manifestations in patients with PIDs are scarce. Hence, the aim this study to investigate lung findings adult and evaluate possible relationship between clinical immunologic features respiratory function these patients. In study, demographic characteristics, serum immunoglobulins (Ig), lymphocyte subgroups, high-resolution computed...
The prevalence and mortality rates of coronavirus disease 2019 (COVID-19) widely vary among populations. Mucosal immunity is the first barrier to pathogen's entry into body. Immunoglobulin A (IgA) primary antibody responsible for mucosal immunity. We explored relationship between selective IgA deficiency (SIgAD) COVID-19 severity. included 424 patients (203 women) with COVID-19. Eleven had SIgAD. Laboratory data SIgAD normal levels were compared. severe infection was using logistic...
With recent advances in genome sequencing technology, a large body of evidence has accumulated over the last few years linking alterations microbiota with cardiovascular disease. In this study, we aimed to compare gut microbial composition using 16S ribosomal DNA (rDNA) techniques patients coronary artery disease (CAD) and stable heart failure (HF) reduced ejection fraction CAD but normal fraction. We also studied relationship between systemic inflammatory markers richness diversity.A total...
Cat and dog allergens are common indoor triggers for respiratory allergies such as allergic rhinitis asthma. This study aims to evaluate the prevalence of cat in adults analyze changes during COVID-19 pandemic.
Background: The main treatment of common variable immunodeficiency (CVID) is to maintain immunoglobulin G (IgG) levels within the target range. However, trough IgG differ among patients with similar body mass index (BMI) and those receiving same dose replacement therapy (IGRT). A crucial factor that underlies these differences presence extensive bronchiectasis, which associated salvage pathway. Objective: We compared in CVID without bronchiectasis who had received IGRT for 2 years determine...
Background: Autoimmune diseases can occur at any time in patients with common variable immunodeficiency (CVID). However, the relationship between low immunoglobulin E (IgE) levels and autoimmune CVID remains poorly understood. Objective: We aimed to determine autoimmunity IgE CVID. Methods: This retrospective cohort study was conducted by using data that had been collected from 62 adult April 2012 December 2021. Serum basal were compared without disease. Results: Overall, 23 of (37.1%) least...
The aim of this study is to determine the prevalence malnutrition in outpatients with common variable immunodeficiency (CVID) and utility nutrition screening tools detect these patients.Fifty CVID were included study. Nutrition risk for each patient was evaluated using four tools: Malnutrition Screening Tool (MST), Universal (MUST), Short Nutritional Assessment Questionnaire (SNAQ), Risk 2002 (NRS-2002).According MUST, MST, SNAQ, NRS-2002, determined be 48% (n = 24), 26% 13), 20% 10),...
Renal cell carcinoma (RCC) has widespread and unpredictable metastatic potential. The most common sites of RCC are the lungs, lymph nodes, bones, liver, brain; however soft tissue metastasis is rare (2,3). Here we report a 76-year-old male patient who had renal presented with gluteal metastasis. To our knowledge this first cancer case at initial diagnosis.
Venom immunotherapy (VIT) is one of the most effective treatment methods for allergic diseases.Neurological symptoms are infrequent among systemic reactions.In this case report, clinical and radiological features a patient who developed acute brainstem ischemia two hours after VIT up-dosing phase were evaluated.A 48-year-old male dyspnea, angioedema, syncope honeybee sting was diagnosed with anaphylaxis.VIT started conventional schedule (depot extract).The went to emergency department due...
Although allergic diseases are generally considered to be of childhood and youth, the first symptoms can seen in old age sometimes. The aim this study was determine prevalence characteristics elderly population admitted allergy unit on an outpatient basis.The files patients who applied our clinic's during 8-year period were retrospectively analyzed. data aged ≥ 65 years obtained from archive.A total 1272 included study. mean 70 (range: 65-97 years). Most female (n = 704, 55.3%). Of patients,...
Many of the prostatic cysts are asymptomatic and only 5% symptomatic (Hamper et al., 1990; Higashi 1990). These symptoms include pelvic pain, hematospermia, infertility, voiding dysfunction, prostatitis-like syndrome, painful ejaculation. Treatment includes TRUSG guided drainage, endoscopic transurethral resection, in some cases even open surgery. In literature, interventions use marsupialization midline cyst with resection (TUR) or incision urethrotomy (Dik 1996; Terris, 1995). Holmium: YAG...
Article Aromatase deficiency in an adolescent girl misdiagnosed as congenital adrenal hyperplasia infancy and childhood was published on July 1, 2014 the journal Journal of Pediatric Endocrinology Metabolism (volume 27, issue 7-8).