A5027859303- Chronic Lymphocytic Leukemia Research
- Plant Pathogens and Fungal Diseases
- Lymphoma Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Acute Lymphoblastic Leukemia research
- SARS-CoV-2 and COVID-19 Research
- Acute Myeloid Leukemia Research
- COVID-19 and healthcare impacts
- Liver Disease Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Multiple and Secondary Primary Cancers
- Testicular diseases and treatments
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Nerve Injury and Rehabilitation
- Multiple Myeloma Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Virus-based gene therapy research
- Pain Management and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Autoimmune and Inflammatory Disorders Research
- Cynara cardunculus studies
- Mycotoxins in Agriculture and Food
- Monoclonal and Polyclonal Antibodies Research
- Wnt/β-catenin signaling in development and cancer
Yanshan University
2025
Mansoura University
2018-2024
King Faisal Specialist Hospital & Research Centre
2024
Asir Central Hospital
2021-2024
Polycythemia is a common medical problem, frequently acquired and reactive to secondary conditions. High-altitude-associated hypoxia contributes the greater prevalence of polycythemia at altitude. Primary clonal vera (PV), even though it rare, requires different therapeutic approach. Suspicion PV usually drives diagnostic workup polycythemia.
Natural killer (NK) function defects have been seen in many hematological malignancies, including acute myeloid leukemia (AML). AML is associated with deficient human leukocyte antigen (HLA) expression on blasts which become targets for killing by NK and natural killer-like T (NKT) cells. However, NKT cells are not effective autologous blasts, maybe due to number or functional abnormalities. The aim of the work was detect percentage patients impact their prognosis, response treatment...
Community-acquired respiratory viral infections (CARV) significantly impact patients with hematological malignancies (HM), leading to high morbidity and mortality. However, large-scale, real-world data on CARV in these is limited. This study analyzed from the EPICOVIDEHA-EPIFLUEHA registry, focusing HM diagnosed during 2023-2024 autumn-winter season. The assessed epidemiology, clinical characteristics, risk factors, outcomes. examined 1312 Of these, 59.5% required hospitalization, 13.5%...
Osteolytic bone lesions and hypercalcemia without peripheral blasts B-cell acute lymphoblastic leukemia (B-ALL) are reported in children but rarely seen adults. Herein, we described two patients with B-ALL presenting symptomatic osteolytic lesions. They were treated by standard induction chemotherapy after correction of supportive measures. With this case reports would like to emphasize the importance clinical awareness as rare presentations ALL. The prognostic implication ALL is unclear...
Microangiopathic hemolytic anemia (MAHA) may occur as a paraneoplastic syndrome in some solid tumors, but MAHA accompanied by signet ring cell carcinoma (SRCC) of an unknown origin is very rare. We report patient who presented with acute onset Coombs negative and frequent schistocytes the peripheral blood smear which are typical for initial presentation metastatic SRCC. Our patients fulfilled criteria thrombotic thrombocytopenic purpura (TTP) received specific treatment TTP without improvement.
The objective of this study is to review the multidetector computed tomography (MDCT) findings synchronous lymphoma and other solid malignancies.This retrospective included 18 patients confirmed with diagnosis malignancies. They were 8 women 10 men (mean age, 62.5 year; range, 44-73 years). CT scanning was performed on one two systems: 64 MDCT in 11 6 7 patients. All 36 malignancies underwent pathological evaluation.All cases pathologically. Lymphomas Hodgkin disease ( n = 5 patients)...
Background: COVID-19 treatment strategies for haematological malignancy patients are adapted from immunocompetent population, without solid evidence. We aimed to describe the efficacy of dexamethasone in a large cohort this population. Methods: Retrospective study multicentre EPICOVIDEHA registry on patients, diagnosed between May 2021 and January 2023. Patients receiving only were compared those plus antiviral strategies. A Cox regression was modelled detect factors associated with...
Background: Fourier Transform Infrared (FTIR) can detect slight change in the biochemical global composition samples taken from patients with Non-Hodgkin’s lymphomas (NHL) including changes carbohydrates, proteins, nucleic acid, lipids or even water. These small might serve early detection before any morphological occur. Patients and methods: The study included (30) diffuse large B-cell (DLBCL) (33) healthy controls. serum were analyzed using FTIR spectroscopy resulted data support vector...
Background: Overexpression of cytokine receptor-like factor 2 (CRLF2) caused by different genetic aberrations has been observed in acute lymphoblastic leukemia (ALL) and correlated with poor outcome. Most patients high CRLF2 expression are clustered the Philadelphia-like (Ph-like) ALL subgroup. Ph-like is reported to be associated alterations IKZF1 gene, encoding transcription Ikaros. Aim: To identify Egyptian determine their prognostic significance. Methods: Peripheral blood samples from 34...
Abstract Background Hepatitis C virus (HCV) infection is a major cause of liver-related morbidity and mortality among thalassemic patients. Direct-acting antiviral agents (DAAs) are highly effective well-tolerated by chronic HCV Results The mean age our patients was 29 years. Sustained virologic response (SVR) at 12 24 weeks achieved in all (100%). most common side effects were fatigue (18%), anemia (13.63%), headache (4.5%). There no statistically significant difference the hemoglobin level...
Abstract Background: (COVID-19) pathophysiology and the predictive factors are not fully understood, but lymphocyte dysregulation appears to play a role. Aim Objectives: To explore clinical value of subset changes in COVID-19 patients’ peripheral blood, which may illustrate pathogenesis COVID-19. Methods: This is prospective cohort study 73 hospitalized patients with confirmed who were classified into two groups: non-severe severe. Lymphocyte subsets (CD3, CD4, CD8, CD19, CD56) assessed...
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is aggressive hematopoietic malignancy derived from the precursors of cells. The present study reported a case 35-year-old BPDCN patient, who presented with scalp lesions without extracutaneous involvement lymph nodes (LNs), peripheral or bone marrow. Histopathological examination lesion revealed monomorphous diffuse infiltrate small to medium-sized cells irregular nuclear contours, pleomorphic nuclei, finely dispersed chromatin,...