A5054295417- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Neuroscience and Neuropharmacology Research
- Vascular Malformations Diagnosis and Treatment
- Retinal Development and Disorders
- Ophthalmology and Visual Impairment Studies
- Retinal and Optic Conditions
- Cell death mechanisms and regulation
- Corneal Surgery and Treatments
- Retinoids in leukemia and cellular processes
- Autophagy in Disease and Therapy
- Calcium signaling and nucleotide metabolism
- Estrogen and related hormone effects
- Ocular Diseases and Behçet’s Syndrome
- Neurological Disorders and Treatments
- Anesthesia and Neurotoxicity Research
- Ubiquitin and proteasome pathways
- RNA regulation and disease
- Inflammatory Biomarkers in Disease Prognosis
- Nuclear Receptors and Signaling
- Renal and Vascular Pathologies
- Photoreceptor and optogenetics research
Akita University
2024-2025
St. Marianna University School of Medicine
2013-2024
The purpose of this study was to compare 27-gauge (27G) with 25-gauge (25G) microincision vitrectomy in patients epiretinal membrane (ERM).ParticipantsSeventy-four eyes 66 undergoing 3-port pars plana using 27G or 25G instrumentation.Seventy-four ERM, who underwent were prospectively evaluated.The mean operation time for significantly longer the group than (9.9±3.5 vs 6.2±2.7 min, respectively, P<0.0001). No statistically significant difference found between two groups terms ERM-inner...
PurposeTo determine whether the inverted internal limiting membrane (ILM) flap technique contributes to high reattachment and closure rates in patients with macular hole-associated retinal detachment (MHRD).Patients methodsIn all, 15 eyes of MHRD undergoing 25-gauge pars plana vitrectomy ILM or peeling. The were divided into group (6 eyes) peeling (9 eyes). logarithm minimal angle resolution best-corrected visual acuity (BCVA) attachment hole compared between two groups before after...
Background/Aims To investigate real-world outcomes for best-corrected visual acuity (BCVA) after 2-year clinical intervention treatment-naïve, centr-involving diabetic macular oedema (DME). Methods Retrospective analysis of longitudinal medical records obtained from 27 institutions specialising in retinal diseases Japan. A total 2049 eyes with treatment-naïve DME commencing between 2010 and 2015 who were followed 2 years eligible. Interventions included anti-vascular endothelial growth...
Purpose: To describe the technique and surgical outcomes of a modified inverted internal limiting membrane (ILM) flap technique, using perfluorocarbon liquid (PFCL) without creating iatrogenic retinal breaks in management macular hole-associated detachment (MHRD). Methods: This retrospective study was approved by Ethics Committee Akita University Hospital. Eight patients with MHRD underwent pars plana vitrectomy (PPV) novel PFCL-assisted ILM technique. Subretinal fluid drained through hole...
Background/aims To investigate the yearly change of real-world outcomes for best corrected visual acuity (BCVA) after 2-year clinical intervention treatment-naïve diabetic macular oedema (DMO). Methods Retrospective analysis aggregated, longitudinal medical records obtained from 27 retina specialised institutions in Japan Survey Treatment DMO database. A total 2049 centre involving eyes which initial started between 2010 and 2015, had been followed 2 years, were eligible. As interventions,...
Netarsudil, a Rho kinase inhibitor with norepinephrine transport inhibitory effect, lowers intraocular pressure, however, its effect on axon damage remains to be elucidated. The aim of the current study was investigate netarsudil TNF-induced loss and examine whether it affects phosphorylated-AMP-activated (p-AMPK) autophagy in optic nerve.Intravitreal administration TNF or carried out rats quantification number determined. Electron microscopy determined autophagosome numbers. Localization...
Purpose To examine the relationship between optical coherence tomography (OCT) images and clinical course in eyes with branch retinal vein occlusion (BRVO) treated intravitreal ranibizumab injection (IVR). Design Prospective cohort study. Participants Thirty of 30 patients BRVO IVR. Methods All received 1 initial IVR followed by repeated injections pro re nata (PRN) regimen. Correlations logarithm minimum angle resolution best-corrected visual acuity (logMAR BCVA) or number IVRs after 12...
Purpose: The Rho kinase inhibitor ripasudil decreases intraocular pressure, although its role in optic nerve axonal damage should be clarified. We therefore investigated whether modulates TNF-induced loss and affects autophagy machinery after the induction of degeneration. Methods: Rats were given intravitreal injection TNF, concomitant hydrochloride hydrate or alone. Axon numbers counted to evaluate effects against axon loss. Immunoblot analysis was performed examine p62 as well LC3-II...
Abstract Backgrounds However there have been numerous investigations of intrascleral intraocular lens (IOL) fixation techniques, is room for improvement in terms simplifying complicated techniques and reducing the high levels skill required. This study aimed to report a novel technique sutureless IOL using retinal forceps with 27-gauge trocar. Methods Nineteen eyes 18 patients underwent from July 2018 September 2019 were enrolled this study. A trocar formed 3-mm scleral tunnels positioned at...
To investigate the efficacy of hemi-temporal internal limiting membrane (ILM) peeling for idiopathic macular hole.The medical records patients with holes who had undergone vitrectomy ILM were studied. Forty-two eyes hole divided into 2 groups based on surgical procedure (hemi-temporal [hemi group]: 15 eyes; 360° [360° 27 eyes). The closure rates and distances between optic disc intersection two retinal vessels most closely located nasally or temporally to compared.The primary not...
In older patients, the management of diabetic macular edema (DME) can be complicated by comorbidities, geriatric syndrome, and socioeconomic status. This study aims to evaluate effects aging on DME.
Purpose: To assess the real-world outcome of best-corrected visual acuity (BCVA) following 2-year intervention for treatment-naïve diabetic macular edema (DME) since approval anti-vascular endothelial growth factor (VEGF) therapy. Methods: A total 1,780 eyes with DME which was initiated between 2015 and 2019, were followed 2 years, extracted from longitudinal medical records 37 retinal disease institutions in Japan. Interventions included anti-VEGF therapy, topical corticosteroid...
<b><i>Purpose:</i></b> To evaluate whether indocyanine green (ICG)-assisted internal limiting membrane peeling affects visual outcome and macular morphologic changes in spectral-domain optical coherence tomography images after hole (MH) surgery. <b><i>Methods:</i></b> A retrospective analysis was performed of 34 eyes patients who had undergone surgical treatment for MH. Best-corrected acuity (BCVA) parameters including central foveal thickness,...
The purpose of this study was to compare straight and angled incisions in 27-gauge microincision vitrectomy patients with epiretinal membrane (ERM).Seventy-three eyes 68 ERM who underwent (35 eyes) or incision (38 for were retrospectively evaluated.No statistically significant difference found between the two groups postoperative logarithm minimal angle resolution best-corrected visual acuity. intraocular pressure rate hypotony 1 day postoperatively did not differ straight- angled-incision...