A5100417040- Animal Virus Infections Studies
- Virus-based gene therapy research
- Wound Healing and Treatments
- Immune Response and Inflammation
- Polysaccharides and Plant Cell Walls
- Ginkgo biloba and Cashew Applications
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related molecular mechanisms research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Animal Behavior and Welfare Studies
- Nutritional Studies and Diet
- Molecular Biology Techniques and Applications
- Cell death mechanisms and regulation
- Genetic Associations and Epidemiology
- Physiological and biochemical adaptations
- Natural product bioactivities and synthesis
- Cardiovascular Health and Risk Factors
- Chromium effects and bioremediation
- Mental Health Research Topics
- interferon and immune responses
- Redox biology and oxidative stress
- Heavy Metal Exposure and Toxicity
- Cell Adhesion Molecules Research
- Glycosylation and Glycoproteins Research
Shandong Agricultural University
2019-2024
Shandong Academy of Chinese Medicine
2023-2024
Nanjing Medical University
2023
Second Affiliated Hospital of Nanchang University
2023
Nanchang University
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Chengdu University of Traditional Chinese Medicine
2022
Zaozhuang Municipal Hospital
2022
Guangdong Ocean University
2022
Gansu Provincial Maternal and Child Health Hospital
2019
Abstract BACKGROUND Heat stress (HS) is known to exert negative effects on the poultry and breeding industry, resulting in severe economic losses. Bile acids (BAs), an important component of bile, play a crucial role improving production performance livestock poultry, alleviating injury, ensuring health poultry. At present, porcine BAs are widely used because their therapeutic HS; however, it remains unclear whether same exerted by sheep BAs, which different from have compositions. In this...
The prevalence and mortality rate of colorectal cancer (CRC) have been increasing dramatically worldwide. Pinus massoniana pollen, a well-known natural food, is one the most commonly consumed traditional medicines in China. P. pollen polysaccharides (PPPS) antitumor effects, but it remains unclear whether they can inhibit CRC. Here, we demonstrated that PPPS inhibited CRC cell proliferation effectively, induced morphology changes, triggered apoptosis by upregulating key apoptosis-related...
Marine environmental change directly affects bivalve growth and survival. Exoskeleton formation, the main energy dissipation in physiological metabolism, typically reflects body of bivalve. However, how bivalves regulate biomineralization exoskeleton under stressors is not yet clear. Long non-coding RNA regulates various life processes through complex mechanisms vertebrates invertebrates. In this research, we cloned complete sequence a mantle-specific expressed long (designated as LncMPEG1 )...
Cardiomyocyte death caused by hypoxia is one of the main causes myocardial infarction or heart failure, and mitochondria play an important role in this process. Agrimonolide (AM) a monomeric component extracted from Agrimonia pilosa L. has antioxidant, antitumor, anti-inflammatory effects. This study aimed to investigate mechanism AM improving hypoxia-induced H9c2 cell damage. The results showed that low concentrations promote proliferation increase cellular ATP content. Transcriptome...
Previously, Carthami Flos and Lepidii Semen(CF-LS) drug pair has been proved effective in inhibiting myocardial fibrosis(MF) by blunting the activity of cardiac fibroblasts. The present study explored underlying mechanism CF-LS MF improving microenvironment based on network pharmacology combined with experimental verification. Active compounds potential targets were retrieved from Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform(TCMSP), obtained GeneCards, Online...
Total polysaccharides of Pinus massoniana Lamb. pollen (PPPSt) is a natural carbohydrate with known anti-inflammatory effects. Inflammation was the main cause death due to myocardial damage caused by sepsis. The aim this study investigate potential protective effect PPPSt on septic injury. Lipopolysaccharide (LPS) injected intraperitoneally establish injury model and PPPS used for intervention, then changes in enzymes, tissue morphology, oxidative stress, inflammation levels were evaluated...
To investigate the regulatory effects and signaling mechanism of sodium ferulate on proliferation apoptosis human skin hypertrophic scar fibroblasts (HSFbs).
Click chemistry was used to study on radiolabeling of 1,2,3-triazole analogs with fac-[Re-188(CO)(3)(H2O)(3)](+). CuSO4/L-sodium ascorbate chosen as the catalyst system, three terminal alkynes were conjugated two different azides respectively, and then new prepared fac-[Re-188(CO)(3)(H2O)(3)](+) coordinated six triazoles. The results showed that radiochemical yields (RCY) conjugation fac-[Re-188(CO)(3)](+) triazoles over 90%, high stability in phosphate-buffered saline new-born calf serum....
Duck circovirus (DuCV) is one of the most prevalent viruses in duck breeding industry, and causes persistent infection severe immunosuppression. Currently, there a serious lack prevention control measures no commercial vaccine against DuCV. Therefore, effective antiviral drugs are important for treating DuCV infection. Interferon (IFN) an component innate immunity, but it remains unclear whether IFN-α has clinical effect Antibody therapy way to treat viral infections. The structural protein...
Preeclampsia (PE) is an idiopathic hypertension syndrome occurring after 20 weeks of gestation. Reports showed that lncRNAs expression was abnormal in preeclampsia. We aimed to investigate the role lncRNA CEACAMP8 proliferation, invasion and migration trophoblast cells improve The cell transfection effects were determined by RT-qPCR analysis. HTR-8/SVneo detected CCK-8 assay, transwell assay wound healing assay. flow cytometry analysis analyzed cycle. Moreover, CDK2, cyclinD1, P21, MMP2,...
Duck circovirus disease (DuCVD) caused by duck (DuCV) is associated with developmental retardation, weight loss, loss of feather, etc., resulting in damage to lymphatic tissues, lymphocytopenia and immunosuppression ducks. However, DuCV being characterized a low viral titer clinically which hinders vaccine development studies on pathogenesis. In order improve this situation, culture (SDDZ17) was conducted vitro vivo , the proliferation characteristics SDDZ17 were optimized obtain greater...