A5049438685- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Dental Radiography and Imaging
- dental development and anomalies
- Oral microbiology and periodontitis research
- Aquaculture disease management and microbiota
- Dental materials and restorations
- Orthopaedic implants and arthroplasty
- Dental Trauma and Treatments
- Oral and gingival health research
- Orthodontics and Dentofacial Orthopedics
- Reconstructive Surgery and Microvascular Techniques
- Electrospun Nanofibers in Biomedical Applications
- Surgical Sutures and Adhesives
- Endodontics and Root Canal Treatments
- T-cell and B-cell Immunology
- Proteoglycans and glycosaminoglycans research
- Hemostasis and retained surgical items
- Oral and Maxillofacial Pathology
- Mesenchymal stem cell research
- 3D Printing in Biomedical Research
- Oral Health Pathology and Treatment
- Silk-based biomaterials and applications
- Hydrogels: synthesis, properties, applications
Yonsei University
2016-2025
Yonsei University College of Dentistry
2016-2025
Yonsei University Dental Hospital
2021-2025
Jeju National University Hospital
2014-2024
Kyungpook National University
2002-2024
Samsung Medical Center
2024
Korea Advanced Institute of Science and Technology
2023-2024
Washington University in St. Louis
2024
Kyung Hee University
2015-2024
Environmental Protection Agency
2024
Abstract Outer membrane vesicles (OMVs) containing various bacterial compounds are released from mainly gram-negative bacteria. Secreted OMVs play important roles in the ability of a bacterium to defend itself, and thus contribute survival bacteria community. In this study, we collected β-lactam antibiotic-resistant Escherichia coli established by conjugation assay parental antibiotic-susceptible strain, performed comparative proteomic analysis examine whether these carried...
The purpose of this study was to determine the clinical, microbial, and radiographic effects local minocycline combined with surgical treatment peri-implantitis. Fifty patients peri-implantitis were recruited, application either or placebo ointment performed. repeated supragingival debridement at 1, 3, 6 mo postoperatively. Plaque index, gingival index (GI), probing pocket depth (PPD), bleeding/suppuration on measured baseline 1-, 3-, 6-mo evaluations. change in supporting bone level (SBL)...
Various synthetic bone substitutes have been developed to reconstruct the bony defects that clinicians often encounter during surgical procedures. Among various substitutes, calcium phosphate (Ca-P) ceramics investigated because their composition and structure are similar those of human bone. We evaluated healing biodegradation patterns three types Ca-P ceramic particle with hydroxyapatite (HA)/β-tricalcium (β-TCP) weight ratio: pure β-TCP, biphasic (BCP) a HA/β-TCP ratio 60/40 (BCP 60/40),...
The aim of this study was to determine the association periodontitis with lifestyle-related comorbidities (LCs) using data in Korean National Health Insurance Cohort Database from 2002 2013. This a retrospective involving large national cohort patient samples (representing 2% total population) stratified on basis sociodemographic information. Using precisely extracted database, correlations between LCs (cerebral infarction, angina pectoris, myocardial hypertension, diabetes mellitus,...
The aim of this study was to determine the osteoconductivity biphasic calcium phosphate collagen composite (BCPC) in rabbit calvarial defect model by comparing with (BCP). Four 8 mm diameter bicortical defects were made ten rabbits. Each randomly assigned and filled 1) sponge, 2) BCP, 3) BCPC, 4) nothing as control. animals sacrificed at either 2 weeks (n = 5) or healing period. All groups showed wedge shaped new bone formation limited area margin both periods. amounts closure similar among...
Several in vivo studies have found that transplanting mesenchymal stem cells (MSCs) into degenerative intervertebral discs (IVDs) leads to regeneration of disc cells. Since the exact underlying mechanisms are not understood, we investigated action MSCs IVDs via paracrine actions. Human and from same donor vertebrae were directly or indirectly cocultured. The multidifferentiation potential, cell proliferation, collagen synthesis, mRNA expression levels assessed. proliferation rates higher...
Abstract Defect‐specific bone regeneration using 3‐dimensional (3D) printing of block has been developed. Polycaprolactone (PCL) is biocompatible polymer that can be used as 3D scaffold. The aim this study to assess the biocompatibility and osteogenic efficacy printed PCL scaffold evaluate effectiveness β‐tricalcium phosphate (β‐TCP) addition in In work, four circular defects (diameter: 8 mm) rabbit calvarium were randomly assigned (1) negative control (control), (2) (PCL), (3) mixed with 10...
Abstract Objectives This study evaluated the dimensional ridge alteration in a buccal‐bone‐deficient extraction socket, and regeneration following socket grafting accompanied by recombinant human bone morphogenetic protein 2 (rh BMP ‐2) or collagen membrane covering. Material Methods In five beagle dogs, entire buccal of extracted sockets premolars was surgically removed immediately grafted using one graft protocols: (1) sham surgery without any grafting, with (2) deproteinized bovine...
Abstracts Background Deproteinized porcine bone mineral (DPBM) was recently developed and commercially available in maxillary sinus grafting, which demineralized bovine (DBBM) widely used. Objectives The present randomized controlled clinical trial aimed to compare histological quality radiographic volume stability sinuses grafted with DPBM DBBM. Materials Methods Twenty 16 participants were enrolled randomly allocated control test groups using sequentially numbered, sealed envelopes;...
Abstract Backgrounds Clinical benefits in bone grafting of intact extraction socket have been widely known, but limited evidence is available for the procedure damaged sockets due to periodontal disease. Purpose This study aimed determine dimensional alteration alveolar ridge following sockets, and compare outcomes using deproteinized bovine (DBBM) versus porcine mineral (DPBM) sockets. Materials Methods One hundred patients ( n = 50 each group) with periodontitis‐induced were included this...
Abstract This study aimed to compare the accuracy and reliability of digital versus conventional clinical measurements width keratinized tissue. To this end, tissue was measured at 110 tooth sites in 5 pig jaws. The were made each site using three-dimensional (3D) scanned images a periodontal probe. actual subsequently on histologic slides prepared from same sites, differences between analyzed determine their two measurement rounds. Furthermore, intrarater interrater reliabilities evaluated...
Gram-negative bacteria have an outer membrane inhibiting the entry of antibiotics. Porins, found within membrane, are involved in regulating permeability β-lactam β-lactamases enzymes that able to inactivate antibacterial properties Interestingly, porins and β-lactamase vesicles (OMVs) β-lactam-resistant Escherichia coli may be survival susceptible strains E. presence antibiotics, through hydrolysis antibiotic. In this study, OMVs isolated from mutants, lacking porin or β-lactamase, were...
The link between periodontitis and intestinal dysbiosis, two factors that contribute to atherosclerosis, has not been clearly defined. We investigated the integrative effects of oral infection with Porphyromonas gingivalis (PG), major pathogen for periodontitis, on microbiota atherosclerosis.ApoE-/- mice were fed a normal chow diet (NC), Western (WD) or WD PG (PG). was by placing total 109 CFUs live into cavity each mouse using feeding needle five times week 3 weeks. Atherosclerotic lesions...
Lee J‐S, Wikesjö UME, Jung U‐W, Choi S‐H, Pippig S, Siedler M, Kim C‐K. Periodontal wound healing/regeneration following implantation of recombinant human growth/differentiation factor‐5 in a β ‐tricalcium phosphate carrier into one‐wall intrabony defects dogs. J Clin Periodontol 2010; 37: 382–389. doi: 10.1111/j.1600‐051X.2010.01544.x Abstract Objective: Recombinant (rhGDF‐5) is being evaluated as candidate therapy support periodontal regeneration. The objective this study was to evaluate...
Abstract Objectives The objective of this study was to elucidate the socket healing process and biodegradation incorporating synthetic bone fillers followed by grafting fresh extraction socket. Materials methods Third premolars in four quadrants eight beagle dogs were extracted randomly treated with either one hydroxyapatite ( HA ), biphasic calcium phosphate BCP β‐tricalcium (β‐ TCP or no graft C ). Histologic observations histomorphometric analysis at three zones (apical, middle, coronal)...
The objectives of this study were to analyze retrospectively the long-term survival and success rates Narrow implants (NIs) placed with various implant systems, association biological technical complications.In total, 338 patients (men = 45.6%, women 54.4%) who received 541 NIs (≤3.5 mm in diameter) for fixed prostheses enrolled retrospective study. mean marginal bone level (MMBL) change was calculated. Life table analysis cumulative rate calculated, complications evaluated.The annual MMBL...