A5058221232- Advanced MRI Techniques and Applications
- Atomic and Subatomic Physics Research
- Rings, Modules, and Algebras
- Fuzzy and Soft Set Theory
- Advanced Algebra and Logic
- Advanced Topics in Algebra
- Fuzzy Logic and Control Systems
- Cardiac Imaging and Diagnostics
- Medical Imaging Techniques and Applications
- semigroups and automata theory
- MRI in cancer diagnosis
- Advanced NMR Techniques and Applications
- Algebraic structures and combinatorial models
- Ultrasound and Hyperthermia Applications
- Lung Cancer Diagnosis and Treatment
- Nuclear Physics and Applications
- Advanced Neuroimaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Photoacoustic and Ultrasonic Imaging
- Commutative Algebra and Its Applications
- HIV-related health complications and treatments
- Cardiovascular Function and Risk Factors
- Food Security and Health in Diverse Populations
- Advanced X-ray Imaging Techniques
- Cardiovascular Disease and Adiposity
National Heart Lung and Blood Institute
2021-2024
National Institutes of Health
2021-2024
Royal Liverpool University Hospital
2024
University of Liverpool
2024
Aintree University Hospitals NHS Foundation Trust
2024
University of South Asia
2022-2023
Ayub Agriculture Research Institute
2023
Shaikh Zayed Hospital
2023
Kyungpook National University
2022
University of Southern California
2013-2021
We demonstrate a novel and robust approach for visualization of upper airway dynamics detection obstructive events from dynamic 3-D magnetic resonance imaging (MRI) scans the pharyngeal airway.This uses region growing, where operator selects interest that includes airway, places two seeds in patent determines threshold first frame.This required 5 s/frame CPU time compared to 10 min/frame manual segmentation. It well with segmentation, resulting Dice Coefficients 0.84 0.94, whereas...
Purpose To develop an isotropic high‐resolution stack‐of‐spirals UTE sequence for pulmonary imaging at 0.55 Tesla by leveraging a combination of robust respiratory‐binning, trajectory correction, and concomitant‐field corrections. Methods A golden‐angle was used to continuously acquire data 15.5 minutes. The binned stable respiratory phase based on superoinferior readout self‐navigator signals. Corrections errors concomitant field artifacts, along with image reconstruction conjugate gradient...
Abstract Purpose To compare T1 and T2 measurements across commercial prototype 0.55T MRI systems in both phantom healthy participants using the same vendor‐neutral pulse sequences, reconstruction, analysis methods. Methods Standard spin echo abbreviated protocol of T1, B1, were made on two 0.55 T an ISMRM/NIST system phantom. Additionally, five imaged at each for measurement. The compared to NMR‐based reference determine accuracy, vivo assess reproducibility differences between systems....
Abstract Purpose To develop an iterative concomitant field and motion corrected (iCoMoCo) reconstruction for isotropic high‐resolution UTE pulmonary imaging at 0.55 T. Methods A free‐breathing golden‐angle stack‐of‐spirals sequence was used to acquire data 8 min with prototype commercial T MRI scanners. The binned into 12 respiratory phases based on superior–inferior navigator readouts. previously published (iMoCo) extended include correction directly in the cost function. implemented within...
Abstract The purpose of this study was to evaluate oxygen‐enhanced pulmonary imaging at 0.55 T with 3D stack‐of‐spirals ultrashort‐ E (UTE) acquisition. Oxygen‐enhanced MRI offers the measurement regional lung ventilation and perfusion using inhaled oxygen as a contrast agent. Low‐field systems equipped contemporary hardware can provide high‐quality structural by virtue prolonged 2 *. Fortuitously, 1 relaxivity increases lower field strengths, which is expected improve sensitivity MRI. We...
Purpose To develop and evaluate an improved velocity‐selective (VS) labeling pulse for myocardial arterial spin (ASL) perfusion imaging that addresses two limitations of current pulses: (1) spurious moving myocardium (2) low efficiency. Methods The proposed VSASL is designed using a Fourier Transform based Velocity‐Selective train. utilizes bipolar velocity‐encoding gradients, 9‐tap envelope, double‐refocusing pulses with Malcolm Levitt phase cycling. Amplitudes the envelope were optimized...
Purpose We propose and evaluate a new structured low‐rank method for echo‐planar imaging (EPI) ghost correction called Robust Autocalibrated LORAKS (RAC‐LORAKS). The can be used to suppress EPI ghosts arising from the differences between different readout gradient polarities and/or shots. It does not require conventional navigator signals, is robust imperfect autocalibration data. Methods previous that uses GRAPPA‐type data enable high‐quality correction. This works well when are pristine,...
Contemporary lower-field magnetic resonance imaging (MRI) may offer advantages for lung by virtue of the improved field homogeneity. The aim this study was to evaluate utility MRI combined morphologic and regional function assessment. We low-field in patients with lymphangioleiomyomatosis (LAM), a rare disease associated parenchymal cysts respiratory failure.We performed on prototype (0.55 T) system 65 LAM. T2-weighted used assessment morphology derive cyst scores, percent parenchyma...
Quantitative assessment of dynamic lung water accumulation is interest to unmask latent heart failure. We develop and validate a free-breathing 3D ultrashort echo time (UTE) sequence with automated inline image processing changes in density (LWD) using high-performance 0.55 T cardiovascular magnetic resonance (CMR). CMR was performed on 15 healthy subjects stack-of-spirals proton weighted UTE at T. Inline reconstruction the Gadgetron framework. A gravity-induced redistribution LWD provoked...
A number of B1 mapping methods have been introduced. model to facilitate choice among these is valuable, as the performance each technique affected by a variety factors, including acquisition signal-to-noise ratio (SNR). The Bloch–Siegert shift method has recently garnered significant interest. In this paper, we present statistical suitable for analysis method. Unlike previously presented models, valid in both low SNR and high regimes. We detailed across broad range scenarios, compare it two...
Background Oxygen-enhanced magnetic resonance imaging (OE-MRI) can be used to assess regional lung function without ionizing radiation. Inhaled oxygen acts as a T1-shortening contrast agent increase signal in T1-weighted (T1w) images. However, proton density from pulmonary hyperoxic vasodilation may also contribute the measured enhancement. Our aim was quantify relative contributions of and vasodilatory effects enhancement OE-MRI both swine healthy volunteers. Methods We imaged 14...
Purpose Exercise‐induced dyspnea caused by lung water is an early heart failure symptom. Dynamic quantification during exercise therefore of interest to detect stage disease. This study developed a time‐resolved 3D MRI method quantify transient dynamics rest and stress. Methods The was evaluated in 15 healthy subjects 2 patients with imaged transitions between exercise, porcine model dynamic extravascular accumulation through mitral regurgitation ( n = 5). Time‐resolved images were acquired...
We used in silico methods to predict the physiochemical and pharmacological characteristics, toxicity, biological activities of screened compounds. All compounds showed positive results while calculating their pharmacokinetic descriptors. Using Prediction Activity Spectra for Substances (PASS) software on form non-oilseed legumes, we identified (mainly 4 polyphenol compounds) with anti-infective, anti-eczematic, antimutagenic, muco-membranous protector, fibrinolytic, anticarcinogenic,...
This study describes an alternative approach to Cartesian SPACE for 1 mm3 isotropic whole brain T2-weighted imaging on a high performance 0.55T scanner. In this technique, the readouts were replaced by interleaved, rotated spiral-in-out trajectories, combined with variable-flip-angle refocusing, echo-reordering, and concomitant gradient compensation. Parallel (PI) compressed sensing (CS) utilized further acceleration. Compared 3D-Cartesian SPACE, method can be leveraged mitigate lower SNR of...
To develop single-slab 3D spiral turbo spin echo (spiral SPACE) for 1-mm3 isotropic whole-brain T2-weighted imaging on a high-performance 0.55T scanner, with high scan efficiency from interleaved spiral-in-out trajectories, variable-flip-angle refocusing radiofrequency (RF) pulses, reordering, and concomitant-field compensation. A stack-of-spirals (in-out waveforms) turbo-spin-echo acquisition was implemented T2-weighed contrast. Gradient infidelity corrected using the gradient impulse...
Motivation: MR denoising using the CNN models often requires abundant high quality data for training. In many applications, such as higher acceleration and low field, is not available. This study overcome this limitation by developing a SNR unit based training scheme novel imaging transformer (imformer) architecture. Goal(s): To develop validate imformer model denoising, enabling generalization across field-strengths, contrasts, anatomy. Approach: architectureResults: Imformer outperformed...