A5091788937- Mental Health Research Topics
- Neurotransmitter Receptor Influence on Behavior
- Behavioral Health and Interventions
- Substance Abuse Treatment and Outcomes
- Heart Rate Variability and Autonomic Control
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Mindfulness and Compassion Interventions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Alcoholism and Thiamine Deficiency
- Neuroscience and Neuropharmacology Research
- Alcohol Consumption and Health Effects
- Impact of Technology on Adolescents
- Receptor Mechanisms and Signaling
- Sex and Gender in Healthcare
- EEG and Brain-Computer Interfaces
- Virtual Reality Applications and Impacts
- Sleep and Wakefulness Research
- Menstrual Health and Disorders
- Gambling Behavior and Treatments
- Non-Invasive Vital Sign Monitoring
- Vagus Nerve Stimulation Research
- Psychological Well-being and Life Satisfaction
- Eating Disorders and Behaviors
- Psychedelics and Drug Studies
Freie Universität Berlin
1995-2024
Charité - Universitätsmedizin Berlin
2017-2024
Humboldt-Universität zu Berlin
2020-2024
HMU Potsdam – Health and Medical University Potsdam
2024
University of Potsdam
2023
Alcohol use disorder (AUD) constitutes a critical public health issue and has sex-specific characteristics. Initial evidence suggests that progesterone estradiol might reduce or increase alcohol intake, respectively. However, there is need for better understanding of how the menstrual cycle in females ratio to males influence patterns individuals with AUD.
Abstract Purpose of Review While the treatment addictive disorders proves to be challenging, new approaches that evolved around concepts mindfulness and acceptance have been utilized investigated in recent years. Our goal is summarize efficacy possible underlying mechanisms mindfulness-based interventions (MBI) disorders. Recent Findings Various meta-analyses suggested MBIs show clinical Considering factors impact disorders, indicated augment responsiveness natural rewards contrast...
Alcohol consumption (AC) leads to death and disability worldwide. Ongoing discussions on potential negative effects of the COVID-19 pandemic AC need be informed by real-world evidence.To examine whether lockdown measures are associated with consumption-related temporal psychological within-person mechanisms.This quantitative, intensive, longitudinal cohort study recruited 1743 participants from 3 sites February 20, 2020, 28, 2021. Data were provided before within second in Germany: (October...
Self-regulation, the ability to guide behavior according one's goals, plays an integral role in understanding loss of control over unwanted behaviors, for example alcohol use disorder (AUD). Yet, experimental tasks that measure processes underlying self-regulation are not easy deploy contexts where such behaviors usually occur, namely outside laboratory, and clinical populations as people with AUD. Moreover, lab-based have been criticized poor test-retest reliability lack construct validity....
Abstract Background The association of impaired dopaminergic neurotransmission with the development and maintenance alcohol use disorder is well known. More specifically, reduced dopamine D2/3 receptors in striatum subjects dependence (AD) compared to healthy controls have been found previous studies. Furthermore, alterations gamma‐aminobutyric acid (GABA) glutamate (Glu) levels anterior cingulate cortex (ACC) AD documented several However, interaction between cortical Glu striatal has not...
According to the reward deficiency syndrome and allostatic hypotheses, hyposensitivity of mesocorticolimbic regions non-alcohol-related stimuli predisposes dependence or is long-lastingly enhanced by chronic substance use. To date, no study has directly compared brain activity during non-drug anticipation between alcohol-dependent, at risk, healthy subjects.Seventy-five abstinent alcohol-dependent human subjects (mean abstinence duration 957.66 days), 62 first-degree relatives individuals,...
Background Aspects of self‐control such as sensation seeking and impaired impulse control have been implicated in alcohol dependence (ALC). Conversely, has ascribed a possible protective role stress‐related psychopathologies. We therefore examined gray matter (GM) morphology individuals with ALC, focusing on differences prefrontal regions that associated self‐control. Additionally, we accounted for lifetime intake regarding measures cortical structures ALC patients. Methods With voxel‐based...
Abstract The ability to accurately perceive one’s own bodily signals, such as the heartbeat, plays a vital role in physical and mental health. However, neurophysiological mechanisms underlying this ability, termed interoception, are not fully understood. Converging evidence suggests that cardiac rhythms linked frontal brain activity, particularly oscillations delta (0.5 – 4 Hz) band, but their causal relationship remained elusive. Using amplitude-modulated transcranial alternating current...
Abstract Background Alcohol use disorder (AUD) belongs to the most burdensome clinical disorders worldwide. Current treatment approaches yield unsatisfactory long-term effects with relapse rates up 85%. Craving for alcohol is a major predictor and can be intentionally induced via cue exposure in real life as well Virtual Reality (VR). The induction habituation of craving conditioned cues extinction learning used Cue Exposure Therapy (CET), long-known but rarely strategy Cognitive Behavioral...
Abstract The modulation of instrumental action by conditioned Pavlovian cues is hypothesized to play a role in the emergence and maintenance maladaptive behavior. Instrumental transfer task (PIT) designed examine magnitude influence on behavior we aim manipulate motivational value reduce their effect responding. To this end, utilized joystick-based modification approach avoidance propensities that has shown success clinical populations. changes PIT, subjected 35 healthy participants series...
<title>Abstract</title> Background Alcohol use disorder (AUD) poses a significant global health challenge. Traditional management strategies often face high relapse rates, leading to need for innovative approaches. Mindfulness-based prevention (MBRP) has emerged as promising intervention enhance cognitive control, reduce cue-related craving and improve interoceptive processing. Neuroimaging studies suggest that mindfulness training can modulate brain networks associated with these factors,...
Background: Acute gamma-aminobutyric acid (GABAergic) effects of alcohol consumption are well-known, whereas prior research has yielded inconsistent findings regarding on adaptations the GABAergic neurotransmitter system to chronic use. Previous studies indicate either elevated or reduced GABA levels in cortical regions such as anterior cingulate cortex (ACC) persons with use disorder (AUD). We tested hypothesis that active compared abstinence contributes observed Methods: investigated ACC...
Abstract Purpose of Review Alcohol use disorder (AUD) is a burdening chronic condition that characterized by high relapse rates despite severe negative consequences. There has been recent emergence interest in (neuro)therapeutic intervention strategies largely involve the detrimental change mechanisms linked to addiction disorders. Most prominently, latter include habitual decision-making, cue-induced behavioral tendencies, as well amplifying effects stressful events on drinking behavior....
Self-regulation, the ability to guide behavior according one’s goals, plays an integral role in understanding loss of control behaviors a pertinent example being substance use disorders (SUD). Yet, experimental tasks that measure processes underlying self-regulation are not easy deploy contexts where such often occur, namely real life situations outside laboratory. Moreover, lab-based criticized for poor test–retest reliability and lack construct validity. These concerns might part explain...
Abstract Background Alcohol use disorder (AUD) is a critical public health issue with sex-specific characteristics and the need for better mechanistic understanding. Initial evidence suggests that progesterone can reduce alcohol intake, while estradiol leads to an increase. However, we lack knowledge about how relative influences patterns in females males AUD. Methods This multicenter within-subject study analyzed data on real-life (21,438 intensively-sampled smartphone entries), menstrual...