A5040918746- Plant Molecular Biology Research
- Plant Reproductive Biology
- Plant Gene Expression Analysis
- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Plant Stress Responses and Tolerance
- Plant Virus Research Studies
- Biochemical and biochemical processes
- Plant biochemistry and biosynthesis
- Bioenergy crop production and management
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Plant Physiology and Cultivation Studies
- Single-cell and spatial transcriptomics
- Immunotherapy and Immune Responses
- Cervical Cancer and HPV Research
- Immune Cell Function and Interaction
- Apelin-related biomedical research
- Plant Genetic and Mutation Studies
- Molecular Biology Techniques and Applications
- COVID-19 Clinical Research Studies
- Plant nutrient uptake and metabolism
- Nuclear Receptors and Signaling
- Seed Germination and Physiology
- Transgenic Plants and Applications
Jilin Agricultural University
2024
Henan University of Science and Technology
2022-2023
Affiliated Hospital of Youjiang Medical University for Nationalities
2021-2022
Hebei Agricultural University
2021-2022
Hangzhou Normal University
2012-2017
Pudong New Area People's Hospital
2015
Populus simonii, a notable native tree species in northern China, demonstrates impressive resistance to stress, broad adaptability, and exceptional hybridization potential. DOF family is class of specific transcription factors that only exist plants, widely participating plant growth development, also playing an important role abiotic stress response. To date, there have been no reported studies on the gene P. expression levels this different tissues poplar, as well its patterns under cold,...
Populus pseudo-cathayana × deltoides is a crucial artificial forest tree species in Northeast China. The presence of the fall webworm (Hyphantria cunea) poses significant threat to these poplar trees, causing substantial economic and ecological damage. This study conducted an insect-feeding experiment with on P. deltoides, examining poplar's physiological indicators, transcriptome, metabolome under different lengths feeding times. Results revealed differences phenylalanine ammonia-lyase...
In plants, non-cell autonomous RNA silencing spreads between cells and over long distances. Recent work has revealed insight on the genetic molecular components essential for cell-to-cell movement of in Arabidopsis. Using a local assay, we report distinct mechanism that may govern short-range (6-10 cell) trafficking virus-induced from epidermal to neighbouring palisade spongy parenchyma Nicotiana benthamiana. This process involves previously unrecognised function RNA-dependent polymerase 6...
Clear cell renal carcinoma (ccRCC) usually affects multiple organs (e.g., bone and brain), patient prognosis is poor. Although it known that CD8+ T infiltration can potentially alleviate ccRCC progression, few studies have concentrated on the correlation between prognosis. In this study, ten genes expressed by infiltrated cells (i.e., AMD1, CCSER2, CIB1, DRAP1, HMGB2, HMGN1, NPIPB5, PTP4A2, RORA , SAP18 ) were suggested as potential prognostic biomarkers, using next-generation sequencing...
High-risk human papillomavirus (hrHPV) infection has been associated with a higher probability of progression to cervical cancer. However, several extensive studies have reported that the presence hrHPV can lead better prognosis, but mechanism how this occurs is unclear. In study, microbiological analysis was used identify HPV as factor for prognosis patients squamous cell carcinoma (CSCC). Comparing interactions + and - malignant cells immune well trajectory either or without HPV, we found...
Drought is one of the main abiotic stress factors affecting yield Paeonia ostii. In this study, we conducted bioinformatics and differential expression analyses P. ostii 'Feng Dan' ptc-miR396g-5p in leaf samples under different drought stress. belongs to miR396 family. Among 271 plant species registered miRBase database, at least member was found 48 Angiospermae species, 3 Gymnospermae 1 Pteridophy. Mature sequence alignment showed that had high similarity with from other species. Secondary...
Virus-induced gene complementation (VIGC), a plant virus technology based on Potato X for transient overexpression of endogenous genes complemented tomato mutants, resulting in non-ripening fruits to ripen. This efficient "gain-of-function" approach involves no stable transformation, and reveals fruit-specific transcriptional network that may exist among key transcription factors modulating ripening. Thus, VIGC represents novel feasible strategy functional analysis plants.
Virus-induced flowering (VIF) uses virus vectors to express Flowering Locus T (FT) induce in plants. This approach has recently attracted wide interest for its practical applications accelerating breeding crops and woody fruit trees. However, the insight into VIF potential as a powerful tool dissecting florigenic proteins remained be elucidated. Here, we describe mechanism further of Potato X (PVX)-based short-day Nicotiana tabacum cultivar Maryland Mammoth. Ectopic delivery Arabidopsis...
CD8+ T cells, which play a vital role in response to adaptive immunity, are closely related the immunization responses kill tumor cells. Understanding effects exerted by tumor-infiltrated cells HPV+ and HPV- head neck squamous cell carcinoma (HNSCC) patients is critical for predicting their prognosis as well towards immunization-related therapy.HNSCC single transcriptome was used screen differentially expressed genes (DEGs) based on A gene signature associated with built verified cancer...
Dwarfism is a desirable trait in eggplant breeding, as it confers higher lodging resistance and allows simplified management harvest. However, few dwarf mutants have been reported, the molecular mechanism underlying dwarfism completely unknown. Here, we report mutant (dwf) isolated from an ethyl methyl sulfonate (EMS)-induced library. The hypocotyl length, plant height, length of internode cells dwf were significantly decreased compared to those wild-type parent ‘14-345’ (WT). Differential...
Head and neck squamous cell carcinoma (HNSCC) usually has a poor prognosis is associated with high mortality rate. Its etiology mainly the result from long-term exposure to either alcohol, tobacco or human papillomavirus (HPV) infection combination of these insults. However, HNSCC patients HPV have been found show survival advantage over those without virus, but mechanism that confers this unclear. Due large number HPV-independent cases, there possibility difference in between HPV-positive...
CD8+ T cells, vital effectors pertaining to adaptive immunity, display close relationships the immunization responses kill tumor cells. Understanding effect exerted by infiltration cells in papillary renal cell carcinoma (papRCC) is critical for assessing prognosis process and therapy cases with this disease.The single-cell transcriptome data of papRCC were used screening T-cell-correlated differentially expressed genes achieve following investigations. On that basis, a gene signature...
Osteoarthritis (OA) is a degenerative disease characterized by articular cartilage and/or chondrocyte destruction, and although it has long been considered as primary disease, the importance of meniscus endothelial cell modulation in subchondral microenvironment recently drawn attention. Previous studies have shown that apelin could potentially inhibit cellular apoptosis; however, remains unclear whether play protective role protecting endothelium OA meniscus. In this study, with advantages...
Leaf size is a crucial trait in eggplant breeding, as it influences photosynthesis, plant biomass and management. However, little known about the molecular mechanism regulating leaf eggplant. This study reports small mutant (slf) generated with mutagen ethyl methane sulfonate (EMS). The slf showed restricted cell proliferation an increased content of auxin. Transcriptome analysis revealed that several genes involved auxin signaling are upregulated slf. Exogenous application auxinole,...
miRNA plays an important role in plant growth and development response to various stresses. Quantitative real-time PCR (qRT-PCR) technology is often used detect the expression level of miRNAs genes by comparing with reference genes. In order screen out optimal different tree peony varieties, petals 42 early- late-flowering varieties were as experimental materials, geNorm, NormFinder, Bestkeeper, RefFinder software evaluate stability 16 candidate miRNAs. The results showed that average Ct...
COVID-19 pneumonia requires effective medical therapies. However, it is a challenge to find therapeutic drugs that not only inhibit viral replication, but also the accompanying cytokine storm and maintain an appropriate immune response. In this study, effects of SARS-CoV-2 on gene expression in lung epithelial cells from patients with were systematically evaluated bioinformatics analysis methods. Transcriptome specific bystander (exposed uninfected) infected found, vital pathways identified...
Populus pseudo-cathayana× deltoides is a crucial artificial forest tree species in Northeast China. The presence of the fall webworm (Hyphantria cunea) poses significant threat to these poplar trees, causing substantial economic and ecological damage. This study conducted an insect-feeding experiment with on P. pseudo-cathayana × deltoides, examining poplar’s physiological indicators, transcriptome, metabolome under different feeding times. Results revealed differences phenylalanine...
The aim of this paper was to investigate the transcriptomic and metabolomic differences in Populus cathayana × canadasis ‘Xinlin1’ (P. ‘Xinlin 1’) under varying irrigation fertilization conditions. Ten-year-old P. 1’ selected as test subject study; different treatments were set up, DEGs DAMs response water fertilizer regulation identified. Transcriptomic profiles analyzed from both leaves roots. A total 22,870 identified treatments, predominantly belonging 48 transcription factor families,...
The flowering period is the most important ornamental trait of tree peony, while industrial development peony has been limited by short period. miR319 plays an regulatory role in plant flowering. In current study, expression characteristics and evolution PsmiR319 was explored using 'Feng Dan' 'Lian He', which are early-flowering late-flowering varieties respectively. structure, evolution, target(s) were analyzed bioinformatics. Evolution analysis showed that pre-PsmiR319 distributed 41...