A5063164898- Heart Failure Treatment and Management
- Liver Disease Diagnosis and Treatment
- Nutrition and Health in Aging
- Blood Pressure and Hypertension Studies
- Cardiac pacing and defibrillation studies
- Gout, Hyperuricemia, Uric Acid
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Sodium Intake and Health
- Thermoregulation and physiological responses
- Congenital Heart Disease Studies
- Renal and Vascular Pathologies
- Coronary Artery Anomalies
- Alcohol Consumption and Health Effects
- Infectious Encephalopathies and Encephalitis
- Inflammation biomarkers and pathways
- Aortic Disease and Treatment Approaches
- Electrical and Bioimpedance Tomography
- Climate Change and Health Impacts
- Ultrasound Imaging and Elastography
- Medical Case Reports and Studies
- Tuberculosis Research and Epidemiology
- Frailty in Older Adults
- Vascular Procedures and Complications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Shimane University
2024
Tottori University
2008-2017
Matsue Red Cross Hospital
2014
E Ink (South Korea)
2013
May Institute
2013
Kanazawa University
1994
Showa University
1994
The clinical significance of nutritional risk assessment in patients with heart failure preserved ejection fraction (HFpEF) remains undefined. Geriatric index (GNRI) is a simple tool for elderly subjects. Its predictive value was evaluated HFpEF, common HF phenotype the population.The present study enrolled 152 consecutive (mean age, 77 ± 11 years; male, 53.9%) who were hospitalized HFpEF at authors' institution. GNRI on admission calculated as follows: 14.89 × serum albumin (g/dl)+41.7×body...
The angiotensin receptor blocker losartan inhibited urate transporter 1 (URAT1) according to in vitro experiments. However, it is still unknown whether the inhibitory effect of on URAT1 contributes its uricosuric action humans. Thirty-two patients with hypertension and nine idiopathic renal hypouricemia (five four without hypertension) were enrolled for this study. Hypertensive prescribed oral (50 mg/day, n = 16) or candesartan (8 16). Before after 1-month treatment, serum concentration...
The kidney becomes atrophic in advanced chronic disease, and renal size parenchymal volume correlate with function. However, alterations have not been adequately studied terms of the cortex medulla. We investigated relationship between changes medulla function.Renal ultrasound (US) parameters including length, thickness, cortical thickness medullary were assessed 176 subjects, who categorized into 4 groups based on estimated glomerular filtration rate (ml/min/1.73 m2): group 1, ≥ 90; 2, 60...
Neutrophils are the predominant leukocyte population in acute inflammation. Granulomatous inflammation such as tuberculosis is a specific type of chronic characterized by accumulation macrophages. To clarify mechanism cellular recruitment inflammation, expression chemokines, interleukin-8 and monocyte chemotactic activating factor (MCAF)/monocyte chemoattractant protein 1 (MCP-1), was examined human blood monocytes response to lipopolysaccharide Escherichia coli, which could induce or...
Acoustic radiation force impulse is a noninvasive method for evaluating tissue elasticity on ultrasound. Renal shear wave velocity measured by this technique has not been fully investigated in patients with renal disease. The aim of the present study was to compare end-stage disease and that without chronic kidney investigate influencing factors.Renal velocities were 59 healthy young subjects (control group), 31 (non-CKD 39 (ESRD group). Each measurement performed 10 times at both kidneys,...
Previous clinical trials have proven beneficial effects of beta-blockers in patients with heart failure (HF) reduced ejection fraction (EF). However, those studies excluded elderly from the subjects or included only a small number them. We assessed whether beta-blocker treatment carvedilol improves survival HF regardless left ventricular EF (LVEF). retrospectively analyzed total 189 older than 75 years who were hospitalized January 2004 to December 2010. Of these, 84 (44%) had been treated...
Several reports have evaluated the association between seasonal variation and acute heart failure (AHF) onset. Cold weather may induce AHF, but clinical characteristics of patients susceptible to AHF during winter not been established. Clinical Scenario (CS) is used in early management so we investigated relationship CS classification onset Japan.We enrolled 582 hospitalized for compared frequency among 4 seasons each group clarify group. Significant increase was seen CS1 (systolic blood...
Abstract Background Extremely low uric acid (UA) levels or increased urinary UA (Uua) excretion might be risk factors for kidney disease in renal hypouricemia (RHU) patients, but their relationship with dysfunction is unclear. This study investigated time-dependent changes eGFR RHU patients. Methods multicenter retrospective assessed metabolism and (median 5.5 years) 13 We then compared change 7 of patients whose could measured 4 years those normouricemic group ( n = 31). In addition, were...
Background: L-carnitine is an essential nutrient that plays a vital role in fatty acid energy metabolism of the heart and skeletal muscles. Primary or secondary carnitine insufficiency contributes to progressive left ventricular systolic dysfunction physical frailty. However, clinical features patients with failure preserved ejection fraction (HFpEF) remain unclear. Objectives: The present study aimed evaluate characteristics outcomes these patients. Design: A prospective cohort study....
Background Diuretics are essential for treating acute decompensated heart failure (ADHF), but the response is inconsistent. This study aimed to clarify whether kidney volume as assessed by ultrasound (US) predicts diuretic resistance in patients with ADHF. Methods We enrolled 29 ADHF and 32 controls. Height-adjusted was US. divided into two groups based on median value of total daily use furosemide (intravenous dose plus 0.5 × oral equivalents) during 3 days from admission. Results Patients...