A5100753342- Advanced Proteomics Techniques and Applications
- Glycosylation and Glycoproteins Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Advanced Frequency and Time Standards
- Advanced biosensing and bioanalysis techniques
- Laser-induced spectroscopy and plasma
- Cancer-related molecular mechanisms research
- Cancer, Hypoxia, and Metabolism
- COVID-19 Clinical Research Studies
- Cold Atom Physics and Bose-Einstein Condensates
- Mass Spectrometry Techniques and Applications
- Advanced Breast Cancer Therapies
- Nanoplatforms for cancer theranostics
- Cancer, Lipids, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Atomic and Subatomic Physics Research
- Ferroptosis and cancer prognosis
- Geophysics and Sensor Technology
- Biosensors and Analytical Detection
- Luminescence and Fluorescent Materials
- Mechanical Behavior of Composites
- Long-Term Effects of COVID-19
- Lung Cancer Treatments and Mutations
- Semiconductor Lasers and Optical Devices
National Institute of Metrology
2013-2025
China Agricultural University
2024-2025
North University of China
2022-2025
Wuhan University
2020-2025
Shanghai Normal University
2025
Nanjing Medical University
2014-2025
Guangxi Medical University
2025
Second Affiliated Hospital of Chengdu University of Traditional Chinese
2025
Institute of Special Animal and Plant Sciences
2024-2025
Chinese Academy of Agricultural Sciences
2024-2025
Exosomes can be efficiently isolated in a short period of time by the specific interaction titanium dioxide with phosphate groups on surface phospholipid bilayer.
ABSTRACT Background: Ferroptosis can have a major impact on the development and advancement of hepatocellular carcinoma (HCC) due to its clear association with heightened vulnerability disease. This study aimed develop novel nanoplatform evaluate effectiveness in vivo vitro models HCC. Methods: Erastin, compound that induces iron-dependent cell death, HMME, sonosensitizer, were enclosed within mesoporous silica nanoparticles (MSNs). The engineered exhibit responsive assembly-disassembly...
A mobile atomic absolute gravimeter NIM-AGRb-1 based on light-pulse atom interferometer has been built, evaluated by the National Institute of Metrology (NIM) China, and participated in pilot study International Comparison Absolute Gravimeters (CCM.G-K2.2017) held at NIM Changping Beijing October 2017. The sensitivity is 44 µGal Hz−1/2 (1 = 10−8 m s−2 ≈ 10−9 g) its instability reaches as small 0.2 when averaged over 30 000 s. instrumental environmental effects were corrected with a total...
BACKGROUND The outbreak of COVID-19 caused by a novel Coronavirus (termed SARS-CoV-2) has spread to over 140 countries around the world. Currently, reverse transcription quantitative qPCR (RT-qPCR) is used as gold standard for diagnostics SARS-CoV-2. However, positive rate RT-qPCR assay pharyngeal swab samples are reported vary from 30∼60%. More accurate and sensitive methods urgently needed support quality assurance or an alternative diagnostic approach. METHODS We established digital PCR...
Abstract Afterglow nanoparticles (AGNPs) possessing inherently long lifetime with tailorable emission colors and uniform size have been sought due to their time‐gating‐free high‐contrast multiplexing imaging. Herein, via a straightforward template method, it is reported that such multicolor AGNPs can be accomplished. The resultant exhibit series of tunable afterglow emissions, including blue, yellow, green, white. These are found highly bright, enabling them perform multichannel imaging in...
Background and Aims Metabolic reprogramming plays an important role in tumorigenesis. However, the metabolic types of different tumors are diverse lack in‐depth study. Here, through analysis big databases clinical samples, we identified a carbamoyl phosphate synthetase 1 (CPS1)‐deficient hepatocellular carcinoma (HCC) subtype, explored tumorigenesis mechanism this HCC aimed to investigate as target for prevention. Approach Results A pan‐cancer study involving differentially expressed genes...
Hepatocellular carcinoma (HCC) is the predominant subtype of primary liver cancer and represents a highly heterogeneous disease, making it hard to predict prognosis therapy efficacy. Here, we established novel tumor immunological phenotype-related gene index (TIPRGPI) consisting 11 genes by Univariate Cox regression least absolute shrinkage selection operator (LASSO) algorithm HCC immunotherapy response. TIPRGPI was validated in multiple datasets exhibited outstanding performance predicting...
Traditional treatments for hepatocellular carcinoma (HCC) still lack effectiveness. Recently, the combined mode of chemodynamic therapy (CDT) and photothermal (PTT) has shown great potential against HCC. However, insufficient Fenton reaction rates hyperthermia-induced heat shock responses greatly impair their efficiency, hindering further clinical application. Here, we constructed a cascade-amplified PTT/CDT nanoplatform by coating an IR780-embedded red blood cell membrane on glucose oxidase...
Objectives: Fitting and forecasting the trend of COVID-19 epidemics. Methods: Based on SEIR dynamic model, considering transmission mechanism, infection spectrum prevention control procedures, we developed SEIR(+CAQ) model to fit frequencies laboratory confirmed cases obtained from government official websites. The data January 20, 2020 February 7, were used while left between 8-12 evaluate quality forecasting. Results: According cumulative number 29 fitting bias for overall China (except...
Owing to their unique afterglow ability, long-wavelength light activatable persistent luminescence (PersL) nanoparticles (PLNPs) have been emerging as an important category of imaging probes. Long-wavelength LED has shown be effective in recharging these nanoparticles. However, finding a simple and method amplify such renewable PersL signals under is still key challenge. Herein, we discovered that dye-sensitization strategy was able effectively boost the NIR emitting ZnGa2 O4 :Cr3+ (ZGC))...
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory 2 (SARS-CoV-2) is still raging all over the world. Hence, rapid and sensitive screening of suspected population in high demand. nucleocapsid protein (NP) SARS-CoV-2 has been selected as an ideal marker for viral antigen detection. This study describes a lateral flow immunoassay (LFIA) based on colloidal gold nanoparticles NP detection, which sensitivity was improved through copper deposition-induced signal...