Guangyu Li

ORCID: 0000-0003-1457-5393
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Hair Growth and Disorders
  • Ruminant Nutrition and Digestive Physiology
  • Gut microbiota and health
  • Meat and Animal Product Quality
  • Dermatologic Treatments and Research
  • Sperm and Testicular Function
  • Genetic and phenotypic traits in livestock
  • Rabbits: Nutrition, Reproduction, Health
  • Reproductive Biology and Fertility
  • Birth, Development, and Health
  • Cancer and Skin Lesions
  • Hedgehog Signaling Pathway Studies
  • Wnt/β-catenin signaling in development and cancer
  • Antioxidant Activity and Oxidative Stress
  • Rangeland Management and Livestock Ecology
  • Artificial Intelligence in Healthcare
  • Hormonal and reproductive studies
  • Skin and Cellular Biology Research
  • Fatty Acid Research and Health
  • Ovarian function and disorders
  • Animal Diversity and Health Studies
  • Aquaculture Nutrition and Growth
  • Selenium in Biological Systems
  • melanin and skin pigmentation

Qingdao Agricultural University
2021-2025

Institute of Special Animal and Plant Sciences
2014-2023

Chinese Academy of Agricultural Sciences
2014-2023

Institute of Agricultural Resources and Regional Planning
2023

Ministry of Agriculture and Rural Affairs
2023

Guiyang Medical University
2023

Affiliated Hospital of Guizhou Medical University
2023

Tianjin Medical University Cancer Institute and Hospital
2021

Shandong University
2012-2020

University of California, Berkeley
2017

To investigate the effect and molecular mechanism of EGF on growth migration hair follicle outer root sheath (ORS) cells.Intact anagen follicles were isolated from mink skin cultured with in vitro to measure ORS daily growth. Meanwhile, purified primary cells treated or transfected EGF, their proliferation assessed by MTT assay transwell assay, respectively. The signaling pathway downstream was characterized using Wnt/β-catenin inhibitor, XAV-939.EGF 2-20 ng/ml, not higher lower, promoted...

10.1159/000445630 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2016-01-01

High throughput sequencing was used to examine the rumen microbiota of sika deer fed high (OLH) and low concentration (OLL) tannin rich oak leaves. The results showed that Prevotella spp. were most dominant bacteria. predominant methanogens members order Methanoplasmatales. protozoa Entodinium longinucleatum, Eudiplodinium maggii, Epidinium caudatum, fungal communities mostly represented by Piromyces Moreover, relative abundance Pseudobutyrivibrio (P=0.026), unidentified bacteria (P=0.028),...

10.1371/journal.pone.0123481 article EN cc-by PLoS ONE 2015-05-08

Acute kidney injury (AKI) is often accompanied by inflammation. Echinacea polysaccharide (EP) an active ingredient that has been demonstrated to possess anti‑oxidative, anti‑inflammatory, antimicrobial and immunomodulatory functions. However, the role of EP in AKI not examined. The present study investigated effects on lipopolysaccharide (LPS)‑induced AKI. Western blotting, immunohistochemistry immunofluorescence analyses were performed detect protein expression levels. Administration...

10.3892/ijmm.2020.4769 article EN cc-by-nc-nd International Journal of Molecular Medicine 2020-10-23

The apparent metabolizable energy(AME), AME corrected to zero-nitrogen retention(AMEn) and net energy (NE) values of corn, soybean meal wheat bran were determined in growing male pheasants with reference diet substitution method. Reference was formulated according standard Pheasants requirement, test diets contained 40 % 20 30 the samples thereference diet. Ninety at age 12 wk similar body weights randomly divided into four groups. heat production metabolism birds measured open-circuit...

10.1016/j.psj.2025.104866 article EN cc-by-nc-nd Poultry Science 2025-02-01

Background: Hair follicles play an essential role in the growth of hair. Epigallocatechin-3-gallate (EGCG), a catechin polyphenol green tea, has various bioactivities. The present study aims to evaluate effect EGCG on mink hair and investigate possible molecular mechanisms. Methods: length was recorded up 6 days presence 0.1-5 μM EGCG. Primary dermal papilla cells (DPCs) outer root sheath (ORSCs) were treated with 0.25-4 EGCG, their evaluated by MTT assay cell cycle detection. levels key...

10.3389/fphar.2018.00674 article EN cc-by Frontiers in Pharmacology 2018-06-26

Despite the deleterious effects associated with elevated carbon dioxide (CO(2)) or hypercapnia, it has been hypothesized that CO(2) can protect lung from injury. However, of chronic hypercapnia on neonatal are unknown. Hence, we investigated effect mouse to identify genes could potentially contribute hypercapnia-mediated protection. Newborn litters were exposed 8% CO(2), 12% room air for 2 wk. Lungs excised and analyzed morphometric alterations. The alveolar walls CO(2)-exposed mice appeared...

10.1152/japplphysiol.01031.2005 article EN Journal of Applied Physiology 2006-08-04

The aim of this experiment was to study the effects different selenium supplemental levels on rumen fermentation microflora sika deer at velvet antler growth stage. A total 20 5-year-old, healthy stage with an average body weight (98.08 ± 4.93) kg were randomly divided into 4 groups, and each group fed in a single house. SY1 control group, SY2 SY3 SY4 basal diet supplemented 0.3, 1.2 4.8 mg/kg selenium, respectively. pretest lasted for 7 days, formal trial period 110 days. results show that:...

10.3390/microorganisms11061444 article EN cc-by Microorganisms 2023-05-30

This study evaluated the cholesterol-lowering property of lactic acid bacteria (LAB) isolated from mink. Two strains, Enterococcus faecium MDF1104 and Lactobacillus plantarum MDL1118, were shown to remove cholesterol broths natural hen egg yolk skimmed milk. The in was reduced by 58.15% 38% L. E. faecium, respectively. When used combination, 48.95% (p < 0.01) removed Experimental mice remained healthy when fed different doses LAB, total serum concentration lowest (0.90 mmol/L) a combination...

10.1139/cjm-2013-0200 article EN Canadian Journal of Microbiology 2013-06-20

The objective of this study was to determine whether nutrient digestibility and reproductive performance pregnant mink (Neovison vison) were affected by different dietary protein levels. One hundred twenty female randomly assigned four groups, receiving diets fresh material with levels, expressed as percentage dry matter (DM), 32, 36, 40 44% respectively. These values corresponded average 320, 360, 400 440 g protein/kg DM, Results follows. All crude digestibility, nitrogen (N) intake, N...

10.1016/j.aninu.2015.05.002 article EN cc-by-nc-nd Animal nutrition 2015-05-21

The regeneration of proliferation potential dermal papilla (DP) cells contributes to the treatment hair loss disorders. Ginkgolide B (GKB) and bilobalide (BB) are two functional components isolated from Ginkgo biloba that can promote growth. In current study, effect GKB or BB on DP cell viability related signaling was assessed. Hair follicles were minks, growth measured under administration BB. minks also subjected induced follicles. increased by as illustrated methyl thiazolyl tetrazolium...

10.1002/biof.1562 article EN BioFactors 2019-09-14

Paeoniae radix alba extract (PRA extract) has the functions of regulating immunity, resisting inflammation, and antioxidant properties. However, current recommendations dietary PRA levels for raccoon dogs were inadequate. The purpose this experimental study was to gain information allowing better estimating effects on dogs, their requirements. Fifty healthy male (120 ± 5) days old randomly divided into 5 groups (group PRA0, PRA1, PRA2, PRA4, PRA8) with 10 animals in each group 1 replicate....

10.3389/fvets.2022.839450 article EN cc-by Frontiers in Veterinary Science 2022-04-04

Myeloid cell leukemia-1 (MCL1), an anti-apoptotic member of the BCL2 family, is expressed abundantly in testis. Previous characterization revealed that MCL1 exclusively Leydig cells mouse testis, yet what it does these remains unknown. We therefore analyzed testosterone biosynthesis isolated primary and MA-10 line, which was knocked down using siRNA strategy. The mRNA abundance steroidogenic genes Star, Cyp11a1, Cyp17a1, Hsd3b1, Srd5a, luteinizing hormone/choriogonadotropin receptor Lhcgr...

10.1002/mrd.22614 article EN Molecular Reproduction and Development 2016-01-06

Abstract Copper has an essential role in normal fur pigmentation and quality. This study evaluated the effects of cupric citrate ( CuC it) supplementation on growth, nutrients metabolism pelt characteristics female silver fox V ulpes fulva ). Fifty age‐matched foxes with similar body weights were randomly divided into five dietary groups for 58 days during winter fur‐growing season. The basal diet contained 4.92 mg/kg copper. Groups I ‐ supplemented 6, 30, 60, 90 or 150 mg C u from it per 1...

10.1111/asj.12208 article EN Animal Science Journal 2014-05-05
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