A5100344724- Gut microbiota and health
- Ruminant Nutrition and Digestive Physiology
- Genomics and Phylogenetic Studies
- Genetic and phenotypic traits in livestock
- Probiotics and Fermented Foods
- Cancer-related molecular mechanisms research
- Genetic diversity and population structure
- Fibroblast Growth Factor Research
- Gout, Hyperuricemia, Uric Acid
- Wildlife Ecology and Conservation
- Plant Molecular Biology Research
- Animal Nutrition and Physiology
- Rangeland Management and Livestock Ecology
- Remote Sensing in Agriculture
- Land Use and Ecosystem Services
- Molecular Biology Techniques and Applications
- Plant and fungal interactions
- Reproductive Physiology in Livestock
- Effects of Environmental Stressors on Livestock
- Remote Sensing and Land Use
- Soil erosion and sediment transport
- Animal Diversity and Health Studies
- Chromosomal and Genetic Variations
- Pancreatic and Hepatic Oncology Research
- Genetic Mapping and Diversity in Plants and Animals
Chinese Academy of Agricultural Sciences
2015-2025
Ministry of Agriculture and Rural Affairs
2021-2025
Jilin Agricultural University
2021-2025
Zhengzhou University
2025
Jilin Agricultural Science and Technology University
2025
Sinopec (China)
2025
Tianjin University
2024-2025
Jiangsu University of Science and Technology
2025
Inner Mongolia University of Science and Technology
2025
Fifth Affiliated Hospital of Zhengzhou University
2025
Phylogeny and characteristics of ruminants Ruminants are a diverse group mammals that includes families containing well-known taxa such as deer, cows, goats. However, their evolutionary relationships have been contentious, the origins distinctive digestive systems headgear, including antlers horns (see Perspective by Ker Yang). To understand among ruminants, L. Chen et al. sequenced 44 species representing 6 performed phylogenetic analysis. From this analysis, they were able to resolve...
The germline mutation rate determines the pace of genome evolution and is an evolving parameter itself1. However, little known about what its evolution, as most studies rates have focused on single species with different methodologies2. Here we quantify across vertebrates by sequencing comparing high-coverage genomes 151 parent-offspring trios from 68 mammals, fishes, birds reptiles. We show that per-generation varies among a factor 40, being higher for males than females in mammals birds,...
Abstract Background Gastrointestinal tract (GIT) microbiomes in ruminants play major roles host health and thus animal production. However, we lack an integrated understanding of microbial community structure function as prior studies are predominantly biased towards the rumen. In this study, used shotgun metagenomics to profile microbiota 370 samples that represent 10 GIT regions seven ruminant species. Results Our analyses reconstructed a reference catalog with > 154 million...
Phylogeny and characteristics of ruminants Ruminants are a diverse group mammals that includes families containing well-known taxa such as deer, cows, goats. However, their evolutionary relationships have been contentious, the origins distinctive digestive systems headgear, including antlers horns (see Perspective by Ker Yang). To understand among ruminants, L. Chen et al. sequenced 44 species representing 6 performed phylogenetic analysis. From this analysis, they were able to resolve...
The annual regrowth of deer antlers provides a valuable model for studying organ regeneration in mammals. We describe single-cell atlas antler regrowth. earliest-stage initiators were mesenchymal cells that express the paired related homeobox 1 gene ( PRRX1 + cells). also identified population “antler blastema progenitor cells” (ABPCs) developed from and directed process. Cross-species comparisons ABPCs several mammalian blastema. In vivo vitro displayed strong self-renewal ability could...
The differences in physiological and immunological parameters pathological damage to organ tissues exposed chronic heat stress provide the basis for evaluating resistance of different chicken breeds (white recessive rock [WRR] Lingshan [LS]). Ninety broilers each breed were divided equally into a group no group. effects on analyzed using flow cytometry, ELISA, RT-qPCR, etc. Under conditions: (1) H H/L values significantly increased (P < 0.01) 2 breeds, higher WRR than LS at late stage 0.05)....
A chromosome-level giraffe genome assembly and gene-edited mice reveal molecular mechanisms underpinning its high stature.
Abstract Background B and K 2 vitamins, essential nutrients in host metabolism, can be synthesized by the rumen microbiome ruminants subsequently absorbed host. However, vitamin biosynthesis whole gastrointestinal their abundances different dietary strategies are largely unknown. Here, we reanalyzed our previous large-scale metagenomic data on of seven ruminant species recruited 17,425 nonredundant microbial genomes from published datasets to gain a comprehensive understanding...
The reindeer is an Arctic species that exhibits distinctive biological characteristics, for which the underlying genetic basis remains largely unknown. We compared genomes of against those other ruminants and nonruminant mammals to reveal light arrhythmicity, high vitamin D metabolic efficiency, antler growth trait females, docility. validate two genes (CYP27B1 POR) show signs positive selection exhibit higher catalytic activity than ruminants. A mutation upstream CCND1 gene endows extra...
Abstract Muntjac deer have experienced drastic karyotype changes during their speciation, making it an ideal model for studying mechanisms and functional consequences of mammalian chromosome evolution. Here we generated chromosome-level genomes Hydropotes inermis (2n = 70), Muntiacus reevesi 46), female male M. crinifrons 8/9) a contig-level genome gongshanensis 8/9). These high-quality combined with Hi-C data allowed us to reveal the evolution 3D chromatin architectures We find that fusion...
Red seaweed contains abundant bioactive ingredients with health benefits. Fermentation is widely used in improving the of materials. However, types active metabolite and changes biological activity components by fermentation process remain unknown. In this study, red Bangia fusco-purpurea was inoculated Lactobacillus delbrueckii plantarum to study supernatants. Results showed that Lactobacillus-fermentation dramatically increased free essential amino acid, trace mineral elements, flavonoids,...
Abstract Background The reindeer (Rangifer tarandus) is the only fully domesticated species in Cervidae family, and it cervid with a circumpolar distribution. Unlike all other cervids, female reindeer, as well males, regularly grow cranial appendages (antlers, defining characteristics of cervids). Moreover, milk contains more protein less lactose than bovids' milk. A high-quality reference genome this will assist efforts to elucidate these important features reindeer. Findings We obtained...
The current study provides the insight into bacteria in gastrointestinal tract (GIT) and methanogens presented rumen cecum of Chinese roe deer (Capreolus pygargus). ruminal, ileal, cecal, colonic contents, as well feces, were obtained from each three, free-range, ingesting natural pasture after euthanasia. For bacterial community, a total 697,031 high-quality 16S rRNA gene sequences generated using high-throughput sequencing, assigned to 2,223 core operational taxonomic units (OTUs) (12...
The dense and diverse community of microorganisms inhabiting the gastrointestinal tract ruminant animals plays critical roles in metabolism absorption nutrients, gut associated immune function. Understanding microbial colonization small intestine new born ruminants is a vital first step toward manipulating function through interventions during early life to produce long-term positive effects on host productivity health. Yet knowledge microbiota its induced metabolites still limited. In...
Yak (Bos grunniens) is an important and dominant livestock species in the challenging environment of Qinghai-Tibetan Plateau. Rumen microbiota solid, liquid, epithelium fractions play key roles nutrient metabolism contribute to host adaptation ruminants. However, there a little knowledge these rumen yak. Therefore, we collected samples dorsal, ventral from five female yaks, then amplified bacterial 16S rRNA gene V4 regions sequenced them using Illumina MiSeq platform. Principal coordinates...
The rumen bacteria in the solid, liquid and epithelial fractions are distinct play important roles degradation of urea nitrogen. However, effects on from three remain unclear. In this study, forty-two Hu lambs were fed a total mixed ration based concentrate roughage (55:45, dry matter basis) randomly assigned to one experimental diets: basal diet with no (UC, 0 g/kg), supplemented low levels (LU, 10 g/kg DM), high (HU, 30 DM). After an 11-week feeding trial, six animals each treatment...
Abstract ABSCISIC ACID-INSENSITIVE3 (ABI3) and ABI5 are 2 crucial transcription factors in abscisic acid (ABA) signaling, their homeostasis at the protein level plays a decisive role seed germination subsequent seedling growth. Here, we found that PLANT U-BOX 8 (PUB8), U-box E3 ubiquitin ligase, physically interacts with ABI3 negatively regulates ABA responses during early Arabidopsis (Arabidopsis thaliana) Loss-of-function pub8 mutants were hypersensitive to ABA-inhibited cotyledon...
The rumen microbiota plays important roles in nutrient metabolism and absorption of the host. However, it is poorly understood how host genetic variation shapes community structure its metabolic phenotype. Here, we used sika deer (Cervus nippon) elk elaphus) to produce following two types hybrid offspring: ♀ × ♂ (SEH) (ESH). Then, examined microbiome metabolites parents their offspring. hybrids differed from that parents, suggesting a significant effect genetics on may have resulted vertical...
High throughput sequencing was used to examine the rumen microbiota of sika deer fed high (OLH) and low concentration (OLL) tannin rich oak leaves. The results showed that Prevotella spp. were most dominant bacteria. predominant methanogens members order Methanoplasmatales. protozoa Entodinium longinucleatum, Eudiplodinium maggii, Epidinium caudatum, fungal communities mostly represented by Piromyces Moreover, relative abundance Pseudobutyrivibrio (P=0.026), unidentified bacteria (P=0.028),...
This study investigated the effects of partially substituting soybean meal (SBM) with incremental amount urea on rumen fermentation, nutrient digestion, plasma metabolites, and growth performance in fattening lambs. Seventy male lambs were sorted into two blocks according to body weight (BW) assigned one five dietary treatments a randomized block design: SBM at 170 g/kg dry matter (DM) or reduced (40 DM) plus 0, 10, 20, 30 g urea/kg DM. Compared receiving diet, fed diet had higher (p <...