A5101472076- Lung Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Asthma and respiratory diseases
- Tracheal and airway disorders
- Occupational exposure and asthma
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Air Quality and Health Impacts
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Salivary Gland Tumors Diagnosis and Treatment
- Occupational and environmental lung diseases
- Respiratory and Cough-Related Research
- Otolaryngology and Infectious Diseases
- Foreign Body Medical Cases
- Head and Neck Anomalies
- Ear Surgery and Otitis Media
- Inhalation and Respiratory Drug Delivery
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Restraint-Related Deaths
- Lung Cancer Treatments and Mutations
- Sarcoidosis and Beryllium Toxicity Research
- Neonatal Respiratory Health Research
- Myasthenia Gravis and Thymoma
Ben-Gurion University of the Negev
2021-2025
Assuta Medical Center
2024-2025
Hebrew University of Jerusalem
1993-2024
Shaare Zedek Medical Center
2014-2024
Clalit Health Services
2023
Tel Aviv Sourasky Medical Center
2010-2021
Tel Aviv University
1998-2019
McGill University Health Centre
2016-2017
Montreal Children's Hospital
2016-2017
McGill University
2017
Idiopathic pulmonary fibrosis is a progressive, fatal disease. This prospective, randomised, double-blind, multicentre, parallel-group, placebo-controlled phase II trial (NCT00903331) investigated the efficacy and safety of endothelin receptor antagonist macitentan in idiopathic fibrosis. Eligible subjects were adults with <3 years duration histological pattern usual interstitial pneumonia on surgical lung biopsy. The primary objective was to demonstrate that (10 mg once daily) positively...
Flexible bronchoscopy is routinely utilized in the diagnosis and treatment of various lung diseases. Nondiagnostic leads to more invasive interventions, such as transthoracic needle aspiration, mediastinoscopy or even thoracotomy. Electromagnetic navigation a novel technology that facilitates approaching peripheral lesions, which are difficult sample by conventional means. The system involves creating an electromagnetic field around chest localizing endoscopic tool using microsensor overlaid...
Background: Bronchoscopy is a minimally invasive method for obtaining biopsies of lung lesions. If biopsy not obtained, more methods such as transthoracic needle aspiration, video-assisted thoracoscopy, or diagnostic thoracotomy are required and they have greater risk complications. In addition, almost half resected lesions benign, in screening programs, this proportion could be above 90%. Thus, the increased complications from techniques must weighed against probability finding benign A...
Chronic obstructive pulmonary disease (COPD) is an inflammatory characterized by a progressive and irreversible deterioration of lung function. Exacerbations COPD have prolonged negative effects on function major impact health status outcomes. NLRP3 inflammasome cardinal component the response, with marked evidence in stable exacerbations COPD. The aim our study was to evaluate activity during exacerbation using vitro model.A549 cells were stimulated different concentrations (10%, 4%, 2%)...
To determine the diagnostic value of percutaneous core needle biopsy (PCNB) in comparison with fine aspiration (FNA) patients benign pulmonary lesions.A retrospective review was undertaken computed tomography-guided PCNBs and FNAs performed between 1988 1997. Both FNA PCNB biopsies were carried out sequentially at same visit every patient.A specific diagnosis made 10/60 cases (16.7%) by 49/60 (81.7%) PCNB. findings resulted significant modification established FNA. The only complication...
Preclinical studies with first-generation adenovirus (Ad) vectors administered in vivo to the respiratory tract have demonstrated a nonspecific host response consisting, part, of parenchymal neutrophil accumulation followed by mononuclear cell and macrophage accumulation. We hypothesized that mechanism for this might be elaboration interleukin-8 (IL-8) monocyte chemoattractant protein-1 (MCP-1) from airway epithelium following exposure Ad. To evaluate hypothesis, we infected A549 cells (a...
(1986). Variable Vocal Cord Dysfunction Presenting as Wheezing and Exercise-Induced Asthma. Journal of Asthma: Vol. 23, No. 5, pp. 241-244.
The authors attempted to determine the utility of percutaneous core needle biopsy (PCNB) compared with fine-needle aspiration (FNA) in diagnosis peripheral lung carcinoma.A retrospective review was undertaken 156 computed tomography (CT)-guided PCNBs and FNAs malignant lesions between 1988-1996. Both CT-guided FNA PCNB biopsies were performed sequentially at same visit for each subject.The reviewed whose specific obtained by 133 cases (85.3%) 121 (77.6%) (P < 0.05). confirmed 90 patients...
T-cell types are important in maintaining immune homeostasis the lung and their imbalance may be associated with several diseases. We examined relationship between bronchoalveolar lavage (BAL) subset profiles clinical course of 46 patients idiopathic pulmonary fibrosis (IPF). A flow cytometry cell sorter (FACS) was used to analyse subsets. Pulmonary function tests (PFT) were performed at baseline 6-12 months later. Patients divided into two groups according CD4/CD8 ratio: >1 (group 1, n=21);...
Objective To describe the current tympanostomy tube insertion (TTI) complication rates occurring within 3 years of surgery in post-intervention era. Current TTI children are based on reports from a meta-analysis that was published 2001, reporting 16 to 26% otorrhea rates, cholesteatoma development 0.7%, and tympanic membrane perforation (TMP) 2.2 16%. Since then, interventions aimed at reducing pediatric otitis media burden have been largely implemented worldwide, indications for published....
Objective: The aim was to study the therapeutic management, recurrence, and need for tonsillectomy in patients who underwent needle aspiration peritonsillar abscess (PTA). Methods: A prospective observational design performed. Patients hospitalized Shaare Zedek Medical Center between years 2004 2007 with a diagnosis of PTA obtaining pus were included. minimum 5-year follow-up required all patients. Recurrences, complications, repeated surgical procedure, length hospital admission, primary...