A5036515552- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Genetic factors in colorectal cancer
- Pancreatitis Pathology and Treatment
- Liver Diseases and Immunity
- Soft tissue tumor case studies
- Inflammatory Biomarkers in Disease Prognosis
- Gastrointestinal motility and disorders
- Pelvic floor disorders treatments
- Sexual function and dysfunction studies
- IL-33, ST2, and ILC Pathways
- Colorectal Cancer Screening and Detection
- Medical Imaging and Pathology Studies
- Metastasis and carcinoma case studies
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Dermatology and Skin Diseases
- Diverticular Disease and Complications
- Urinary Bladder and Prostate Research
- Pancreatic and Hepatic Oncology Research
Sumitomo Besshi Hospital
2011-2025
National Institute of Technology, Niihama College
2024
Ehime University
2023-2024
Ehime University Hospital
2024
Saiseikai Ibaraki Hospital
2024
Ehime Prefectural Central Hospital
2024
Evidence (Italy)
2023
Michigan Department of Education
2023
American Urological Association
2023
Shiga University of Medical Science
2010
Abstract Background and Aim Although oral mesalamine is the first‐choice drug for treating mild‐to‐moderate ulcerative colitis (UC), some patients show symptoms of intolerance, including exacerbation diarrhea abdominal pain. The present study clarified current state clinical courses with intolerance. Methods Patients who were diagnosed UC administered at eight hospitals in Japan a follow‐up period exceeding 1 year analyzed. Results Sixty‐seven (11%) 633 showed intolerance to least one...
Patients with primary intestinal follicular lymphoma are often followed-up without a specific treatment, and this approach is called the "watch-and-wait approach." However, long-term outcomes of patient group have not been sufficiently investigated. We enrolled patients who were diagnosed before 2016 managed watch-and-wait in 20 institutions. retrospectively investigated overall, disease-specific, event-free survival rates as well rate spontaneous regression. Among 248 gastrointestinal...
Allergic diseases and ulcerative colitis (UC) share pathophysiological similarities. This study aimed to investigate the unclear association between allergic mucosal healing (MH), an important factor in prognosis of UC. We studied 289 Japanese patients with Information on (bronchial asthma, atopic dermatitis, pollen allergy, food drug allergy), as diagnosed by physicians, was collected through self-reported questionnaires. The definition MH Mayo Endoscopic Score 0. each disease its...
A solitary Peutz-Jeghers-type hamartomatous polyp in the duodenum is rare, and few reports have described its characteristic endoscopic features.We describe three cases of their findings detail.The all our showed an irregularly lobular or nodular surface, whereas adenomas often show a regularly granular surface.The color was whitish cases.In present cases, close observation by endoscopy revealed that polyps looked because presence diffusely scattered white spots on surface polyps.Duodenal...
Abstract Background and Aim Although diet is one of the potential environmental factors affecting ulcerative colitis (UC), evidence not sufficient to draw definitive conclusions. This Japanese case–control study examined association between consumption coffee, other caffeine‐containing beverages food, total caffeine risk UC. Methods The involved 384 UC cases 665 control subjects. Intake decaffeinated black tea, green oolong carbonated soft drinks, chocolate snacks was measured with a...
Asymptomatic colonic metastases from
To evaluate the effectiveness of endoscopic submucosal dissection using an insulation-tipped diathermic knife (IT-ESD) for treatment patients with gastric remnant cancer.Thirty-two early cancer in stomach, who underwent distal gastrectomy due to carcinoma, were treated mucosal resection (EMR) or ESD at Sumitomo Besshi Hospital and Shikoku Cancer Center 10-year period from January 1998 December 2007, including 17 IT-ESD. Retrospectively, patient backgrounds, one-piece rate, complete (CR)...
Collagenous colitis is a distinct clinicopathologic entity characterized by chronic watery diarrhea and, histologically, the subepithelial deposition of collagen [1] [2]. Some luminal antigens, including nonsteroidal anti-inflammatory drugs (NSAIDs) and proton pump inhibitors (PPIs), particularly lansoprazole, are thought to contribute development collagenous colitis. On endoscopy, usually shows no or minimal nonspecific abnormalities. However, recent report showed that "linear mucosal...
Clinical characteristics and prognosis of patients with a solitary Peutz-Jeghers polyp (PJP) have not been fully investigated.Solitary PJP was diagnosed when single hamartomatous lesion identified in the gastrointestinal tract without mucocutaneous pigmentation or family history syndrome. We retrospectively reviewed 51 (32 men 19 women) analyzed sex, age at diagnosis, endoscopic features, outcomes this patient group. The STK11/LKB1 germline mutation investigated any patients.The mean 66.1...
A simple serum biomarker for clinical outcome in patients with ulcerative colitis (UC) remains an unmet need. Some studies have shown association between C-reactive protein (CRP)-albumin ratio (CAR) and prognosis inflammatory bowel disease (IBD), but evidence regarding the CAR UC limited. We evaluated Japanese UC.Subjects were 273 UC. Clinical remission was defined as absence of both abnormally high stool frequency (< 3 per day) rectal bleeding. Mucosal healing (MH) Mayo endoscopic subscore...
Despite progress in medical treatment for ulcerative colitis, a considerable fraction of colitis patients undergo colectomy. We analyzed the clinical variables and determined risk factors indications colectomy.The records 981 consecutive Japanese with were reviewed both retrospectively prospectively.Of 85 underwent Multivariate analysis indicated that male gender (risk ratio, 2.16; 95 percent confidence interval, 1.37-3.42), onset year during after 2000 2.85; 1.31-6.22), severe disease...
Gastric inflammatory fibroid polyps (IFPs) are rare benign lesions that occur in the distal stomach. We describe a 56-year-old woman with Helicobacter pylori (H. pylori)-positive gastric IFP treated eradication. Endoscopic examination revealed submucosal tumor, 35 mm diameter, an ulcerated apex at antrum. H. were positive by both histology and tissue culture, eradication (a proton pump inhibitor, amoxicillin, clarithromycin) was performed. After 6 months, tumor morphologically changed...
A 31-year-old woman who had ingested a toothpick consulted our hospital because of epigastralgia. An abdominal computed tomography (CT) demonstrated penetrating the gastric wall. Endoscopic examination an protruding from prepyloric antrum. The whole was removed using basket catheter without complications. CT images were useful to acquire clinical information such as location end. Unintentional ingestion toothpicks must be considered potentially dangerous. locations both ends should confirmed...
We describe an 87-year-old woman with a large ileal gastrointestinal stromal tumor (GIST) causing hemoperitoneum.A CT scan demonstrated heterogeneous mass measuring about 13 cm × 11 in the pelvis and hemoperitoneum, non-uniform enhancement pattern.The was diagnosed as GIST originating from tract.She underwent urgent laparotomy rupture found 130 anal to Treitz's ligament.Hemoperitoneum caused by is rare condition.Bleeding leading of capsule might cause hemoperitoneum present case.
Abstract Background Mucosal healing (MH) has been indicated as the therapeutic goal for ulcerative colitis (UC). Platelet count is known an inflammation evaluation. However, association between platelet and MH among patients with UC still scarce. We therefore assessed this issue Japanese UC. Methods The study subjects consisted of 345 was divided into quartiles on basis distribution all (low, moderate, high, very high). Several endoscope specialists were responsible evaluating partial MH,...
Objective Serum albumin is used as a marker of acute inflammation. Several studies have addressed the association between serum and clinical outcome in patients with ulcerative colitis (UC). While mucosal healing (MH) has been indicated therapeutic goal for UC, MH remains unclear. We evaluated this issue UC overall explored whether duration affected association. Design This cross-sectional study recruited consecutive UC. Study subjects consisted 273 Japanese was divided into tertiles based...
The representative endoscopic features of primary intestinal follicular lymphoma are well known as small whitish polypoid nodules, but a magnified view has only been described in few case reports.Herein, we report with which magnifying endoscopy narrow band imaging was helpful for prompt diagnosis.A 57-yearold Japanese woman underwent surveillance esophagogastroduodenoscopy.The examination revealed confluent granules the duodenum, distinct from nodules or polyps that typical findings...
Abstract Background and Aim Although previous studies compared the efficacy of infliximab (IFX) versus adalimumab (ADA) as first‐line biologics for Crohn's disease (CD), difference in long‐term prognosis based on which biologic was used first has scarcely been reported. In particular, clinical courses after loss response (LOR) are largely unknown. Methods A multicenter, retrospective study performed. Disease biologic‐naïve CD patients who were started IFX or ADA treatment evaluated, even LOR...
Monocytes play an important role in innate immunity. Some epidemiological evidence indicates association between peripheral blood monocytes and ulcerative colitis (UC). The mucosal healing (MH), however, remains unclear. We evaluated this issue patients with UC. Study subjects consisted of 272 Japanese Monocyte counts were taken the morning after overnight fasting. count was divided into tertiles based on distribution values among all study subjects. Information clinical remission obtained...
Although an inverse relationship between current smoking and the development of ulcerative colitis (UC) has been shown in North America Europe, evidence is limited Asian countries, where incidence UC rapidly increasing. This Japanese case-control study examined association active passive risk UC.A self-administered questionnaire was used to obtain information on potential confounding factors 384 cases with a diagnosis within past 4 years 665 controls.Compared having never smoked, ever smoked...