A5101879594- Neonatal Respiratory Health Research
- Anesthesia and Neurotoxicity Research
- Mycobacterium research and diagnosis
- Advanced Fiber Optic Sensors
- Silicon Carbide Semiconductor Technologies
- Trauma Management and Diagnosis
- Coal Properties and Utilization
- Immune Cell Function and Interaction
- Photonic and Optical Devices
- Cancer Research and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Metallurgy and Material Forming
- Tuberculosis Research and Epidemiology
- Advanced Photonic Communication Systems
- Traffic Prediction and Management Techniques
- Transportation Planning and Optimization
- Neuroinflammation and Neurodegeneration Mechanisms
- HVDC Systems and Fault Protection
- Traffic control and management
- Congenital Diaphragmatic Hernia Studies
- Nerve injury and regeneration
- High Entropy Alloys Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Gaussian Processes and Bayesian Inference
- Treatment of Major Depression
Xi'an Jiaotong University
2012-2024
Chinese Academy of Agricultural Sciences
2024
Institute of Plant Protection
2024
Chongqing Medical University
2024
Children's Hospital of Chongqing Medical University
2024
Institute of Zoology
2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Southeast University
2006-2024
Nanyang Institute of Technology
2024
Abstract Objective: The senescence of nucleus pulposus (NP) cells induced by oxidative stress is one the important causes intervertebral disc degeneration (IDD). Herein, we investigated role and action mechanism silent information regulator 1 (SIRT1) in stress-induced rat NP cell. Methods: Premature was sublethal concentration hydrogen peroxide (H2O2) (100 μM). SIRT1 activated with SRT1720 (5 μM) to explore its effect on senescence. FoxO1 Akt were inhibited AS1842856 (0.2 MK-2206 μM),...
Background Observational studies have demonstrated an association between white blood cells (WBC) subtypes and type 2 diabetes (T2D) risk. However, it is unknown whether this relationship causal. We used Mendelian randomization (MR) to investigate the causal effect of WBC on T2D glycemic traits. Methods The summary data for neutrophil, lymphocyte, monocyte, eosinophil, basophil counts were extracted from a recent genome-wide study (n = 173,480). DIAGRAM MAGIC consortia offered pertaining...
In this paper, we proposed an all-sapphire-based extrinsic Fabry-Perot interferometer (EFPI) pressure sensor based on optimized wet etching process, aiming to improve the quality of interference signal. The sapphire sensitive diaphragm (SPSD) was fabricated by solutions with different mixture ratios H 3 PO 4 and 2 SO at 280°C. differences affect surface roughness SPSD. SPSDs 3.91nm 0.39nm are obtained when is 1:1 1:3, respectively. We constructed sensing test system adopting these two kinds...
DC circuit breakers (DCCBs) are the key equipment to rapidly interrupt fault current in high-voltage power grids and ensure safe operation of system. However, most DCCBs do not take current-limiting measures rely solely on reactors system limit rate rise during interruption process. The extensive use fully controlled electronic devices (CBs) results high costs. To address issues above, this paper proposes a DCCB topology with function based thyristors diodes, which can reduce cost CB while...
Large‐capacity high voltage direct current circuit breakers (HVDC CBs) are critical equipment for achieving reliable operation of future multiterminal HVDC systems. The objective this paper is to investigate the interruption characteristics DCCB with parallel vacuum interrupters. In paper, proposed interrupter modeled in detail and simulated PSCAD environment by taking into account positive volt‐ampere arc, transfer characteristics, sharing between Then, model validated experimental results....
Congestion pricing is perceived as an economic instrument for transportation demand management in alleviating urban traffic congestion, and has received increasing attention both academically practically recent years. Compared with the conventional static congestion models, dynamic (DCP) models are more rational effective due to inherent uncertainty, randomness time-varying properties, of systems. The theory, methods, used DCP reviewed. According timescale distribution, can be classified...
Lung cancer remains the leading cause of death worldwide. Late diagnosis, chemoresistance, and metastasis are main reasons for high mortality rate lung cancer. Therefore, development other treatments is urgent. Cediranib (CED), a vascular endothelial growth factor receptor (VEGFR) kinase inhibitor, shows promising antitumour activities in various cancers including Here, we explored effects underlying molecular mechanism CED on non-small-cell (NSCLC) cell line A549 cells vitro. Our results...
Purpose: To investigate the levels of pregnancy-associated plasma protein A (PAPP-A) or insulin-like growth factor -1 (IGF-1) in patients with acute coronary syndrome. Methods: Serum PAPP-A and IGF-1 was measured biotin–tyramide-amplified enzyme immunoassay Enzyme Linked Immuoserbent Assay, respectively, ST elevation myocardial infarction (STEMI, n=12), unstable angina (UAP, n=15), stable (n=15). also 16 healthy subjects (control group). Results: The serum STEMI (16.9±10.3 mIU/L) UAP group...
Pressure injury (PI) affects quality of life and results in economic social burdens. Local transplantation human adipose-derived stem cells (ASCs) is considered an effective treatment. However, ASC suspension alone vulnerable to the immune system a shortened cell survival. There increasing evidence synergistic effect platelet-rich plasma (PRP) combined with ASCs on wound healing. This study investigated effectiveness, synergy, mechanism healing following local injection PRP rodent PI model....
Radiotherapy is an important therapeutic method for lung cancer. However, in clinical situations, cellular resistance to radiotherapy a significant component of tumor treatment failure. Thus, clarification mechanism underlying radiosensitivity cancer cell urgently needed. In this study, we established radiation model Lewis carcinoma C57BL/6 mice and investigated the possible signaling molecule involved process.C57BL/6 were subcutaneously transplanted with cells locally irradiated followed by...
Brown adipose tissue (BAT) is a major site of non-shivering thermogenesis in mammals and plays an important role energy homeostasis. Nuclear factor-erythroid 2-related factor 1 (NFE2L1, also known as Nrf1), master regulator cellular metabolic homeostasis numerous stress responses, has been found to function critical driver BAT thermogenic adaption cold or obesity by providing proteometabolic quality control. Our recent studies using adipocyte-specific Nfe2l1 knockout [Nfe2l1(f)-KO] mice...