A5042505907- Neurological Disorders and Treatments
- Pharmacological Effects of Natural Compounds
- Diabetes Treatment and Management
- Acute Ischemic Stroke Management
- Healthcare Systems and Public Health
- Diabetes Management and Research
- Virus-based gene therapy research
- Botulinum Toxin and Related Neurological Disorders
- Chemical synthesis and pharmacological studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Botanical Studies and Applications
- Regulation of Appetite and Obesity
- Medicinal plant effects and applications
- Cervical Cancer and HPV Research
- Therapeutic Uses of Natural Elements
- Medicinal Plant Pharmacodynamics Research
- Medicinal Plants and Bioactive Compounds
- Poisoning and overdose treatments
- Paraoxonase enzyme and polymorphisms
- Surgical Sutures and Adhesives
- Phytochemical and Pharmacological Studies
- Biochemical Analysis and Sensing Techniques
- Atherosclerosis and Cardiovascular Diseases
- Hepatitis B Virus Studies
- Tryptophan and brain disorders
Privolzhsky Research Medical University
2015-2025
Izhevsk State Medical Academy
2019-2020
Udmurt Federal Research Center, Ural Branch of the Russian Academy of Sciences
2019-2020
Laboratoire de Synthèse Organique
2019
Institute of Normal and Pathological Physiology of the Slovak Academy of Sciences
2015-2019
Sechenov University
2019
Lomonosov Moscow State University
2019
Udmurt State University
2019
Living Systems (United States)
2015
Diabetes mellitus (DM) is one of the most common pathologies today. According to Federal Register Mellitus, number patients increases by about 5% every year. As a rule, medical history complicated presence other concomitant pathologies. And this applies not only cardiovascular diseases, but also lipid metabolism disorders (dyslipidemia, obesity, atherosclerosis), uric acid and excretion (hyperuricemia, gout). There was clear correlation between complications diabetes atherosclerosis due an...
The mechanism of action drugs is traditionally considered the specific main active ingredients. Therefore, to study drugs, specialists use selected chemical compounds in chemically pure form. However, at beginning 21st century, studies have reported that dosage forms (tablets, solutions, etc.) different from fact tablets, and other contain not only ingredients but also auxiliary, shape-forming ingredients, gases supplement with their nonspecific action. penetrate air; however, can be...
Introduction. A review of the scientific literature showed that current standards for assessing quality drugs does not include an assessment osmotic activity drug solutions and their local irritant effect on tissues at sites subcutaneous, intramuscular intravenous injections. Therefore, currently injectable considered to be high may have isotonic postinjection safety. Text. study concentration range ready injection acceptable value main ingredients is in 0.01 76 %. Direct measurement with...
The aim of the study was to determine possibility infrared monitoring dynamics local temperature in fetal head skin at final stage physiological delivery order assess degree arterial blood and oxygen supply fetus brain.Materials Methods.Infrared surface carried out Maternity Hospital No.6 Republic Clinical Diagnostic Center (Izhevsk, Russia) 35 women (sometimes called bearing-down or pushing, transitional labor) immediately after childbirth.Infrared tomography used control temperature.The...
This review is devoted to a problem of interpretations scientific data in the field genes polymorphism researches, especially endothelial nitric oxide synthase. It difficult evaluate gene associations with variety clinically significant conditions. To define essential patients diabetes mellitus because its cardiovascular complications. The about gives us abilities develop new targets and tactics, providing personal approach disease management.
The aim of the investigation was to study in experiment total toxicity and immunological safety a novel domestic therapeutic vaccine against recurrent respiratory papillomatosis anogenital condylomatosis, injected intramuscularly.Materials Methods.we studied acute by following parameters: clinical presentation intoxication, median lethal dose size, change body weight surviving animals; chronic -by dynamics general condition animals, weight, hematological biochemical indices peripheral blood,...
The aim of the research was to study potential response pharmacotherapy in patients with type 2 diabetes mellitus considering single nucleotide polymorphisms genes encoding for endothelial nitric oxide synthase, 8-oxoguanine DNA glycosylase, and p53 protein as well their combinations.Materials Methods.A total 89 newly diagnosed before start 80 diabetes-free individuals were examined.Single protein, combinations polymorphic genes, tested.Results.The occurrence rate above is close that...
Согласно законодательству Российской Федерации широкий спектр специальностей подвергается лабораторному исследованию на наличие наркотических и психотропных веществ в биологических жидкостях. В большинстве случаев для данной цели используют иммунохроматографический анализ, существенным недостатком которого является возможность ложноположительного результата тестирования. Причиной тому могут служить кросс-реакции, происходящие организме из-за приема лекарственных препаратов, не относящихся к...
Chronic hyperglycemia imposes damage on a number of cell types and is strongly correlated with the variety related complications such as eyes, kidneys, cardiovascular system etc. This fact implies pharmacological treatment. Some are metabolic neutral, some apt to provoke hypoglycemia and/or hyperglycemia, invert response. To take into account potential role treatment glucose level crucial for pharmacotherapy in patient T2DM. Besides, drugs may distort meaning lab tests.
Diabetes mellitus is a predictor of the severe course new coronavirus infection and high mortality, in this regard, selection appropriate hypoglycemic therapy vital issue. In article, we paid attention to dipeptidyl peptidase-4 (DPP-4) inhibitors, since group drugs has features like low risk hyperglycemia immuno-mediated effects. For most effective treatment, it necessary take into account individual characteristics each patient, namely, achievements pharmacogenetics. The genetic variability...
Combined pathology is a real problem for rational pharmacotherapy due to multiple organ damage. The need affect simultaneously several pathogenesis processes leads polypharmacy that can appear be less effective, toxic and unacceptable in some time. For comorbid patients with long - term ongoing type 2 diabetes mellitus (T2DM), the of drug interactions as relevant selection optimal hypoglycemic therapy. This review aims identify opportunities optimize therapy increase effectiveness...